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The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

A molecular rotor mechanism is proposed to explain weak magnetic field effects in biology. Despite being nanoscale (1 nm), this rotor exhibits quantum superposition and interference. Analytical modeling shows its quantum dynamics are highly…

生物物理 · 物理学 2025-12-18 V. N. Binhi

The small world of matter is getting smaller and smaller. Nano sciences in recent years had huge developments allowing nanotechnologies to take enormous steps in the development of materials and processes. Numerous applications in a wide…

物理与社会 · 物理学 2021-11-08 José António Filipe , Manuel Alberto M. Ferreira

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

分子网络 · 定量生物学 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

The mechanics of crawling cells on a substrate is investigated by using a minimal model that satisfies the force-free condition. A cell is described by two subcellular elements connected by a linear actuator that changes the length of the…

软凝聚态物质 · 物理学 2018-04-18 Mitsusuke Tarama , Ryoichi Yamamoto

In vivo, eukaryotic cells are embedded in a matrix environment, where they grow and develop. Generally, this extracellular matrix (ECM) is an anisotropic fibrous structure, through which macromolecules and biochemical signaling molecules at…

生物物理 · 物理学 2020-01-06 David Gomez , Sari Natan , Yair Shokef , Ayelet Lesman

This article frames the relation between biology and physics by characterizing the former as a subdiscipline rather than a special case of the latter. To do this, we posit biological physics as the science of living matter in contrast to…

生物物理 · 物理学 2026-03-16 Stuart A. Newman , Sahotra Sarkar

In living systems, we often see the emergence of the ingredients necessary for computation -- the capacity for information transmission, storage, and modification -- begging the question of how we may exploit or imitate such biological…

神经元与认知 · 定量生物学 2020-09-11 Kristine Heiney , Gunnar Tufte , Stefano Nichele

Improved understanding of molecular systems has only emphasised the sophistication of networks within the cell. Simultaneously, the advance of nucleic acid nanotechnology, a platform within which reactions can be exquisitely controlled, has…

分子网络 · 定量生物学 2017-10-03 Thomas E. Ouldridge

Nano-machines circulating inside the human body, collecting data on tissue conditions, represent a vital part of next-generation medical diagnostic systems. However, for these devices to operate effectively, they need to relay not only…

信息检索 · 计算机科学 2025-09-16 Krzysztof Skos , Albert Diez Comas , Josep Miquel Jornet , Pawel Kulakowski

Micromotor and nanomotor particles are typically made using dense solid particles that can sediment or be trapped in confined flow environments. Creation of much larger motors should be possible if a very low-density system is used with…

软凝聚态物质 · 物理学 2022-06-08 Maryam Hosseini , Firoozeh Babayekhorasani , Ziyi Guo , Kang Liang , Vicki Chen , Patrick T. Spicer

Self-propelled nanoparticles moving through liquids offer the possibility of creating advanced applications where such nanoswimmers can operate as artificial molecular-sized motors. Achieving control over the motion of nanoswimmers is a…

统计力学 · 物理学 2023-11-27 Artem Ryabov , Mykola Tasinkevych

The high energy consumption of electronic data processors, together with physical challenges limiting their further improvement, has triggered intensive interest in alternative computation paradigms. Here we focus on network-based…

Thermally driven nanotube nanomotors provide linear mass transportation controlled by a temperature gradient. However, the underlying mechanism is still unclear where the mass transportation velocity in experiment is much lower than that…

介观与纳米尺度物理 · 物理学 2014-08-01 Jige Chen , Yi Gao , Chunlei Wang , Renliang Zhang , Hong Zhao , Haiping Fang

The concept of utilizing a molecule bridged between two electrodes as a stable rectifying device with the possibility of commercialization is a "holy grail" of molecular electronics. Molecular rectifiers do not only exploit the electronic…

The persistent motility of the individual constituents in microbial suspensions represents a prime example of so-called active matter systems. Cells consume energy, exert forces and move, overall releasing the constraints of equilibrium…

生物物理 · 物理学 2020-11-02 Armand Javadi , Jorge Arrieta , Idan Tuval , Marco Polin

The importance of molecular-scale forces in sculpting biological form and function has been acknowledged for more than a century. Accounting for forces in biology is a problem that lies at the intersection of soft condensed matter physics,…

软凝聚态物质 · 物理学 2025-12-10 K. Vijay Kumar , Mandar M. Inamdar , Pramod A. Pullarkat , Gautam I. Menon

Along with recent progress in structural biology and genome biology, structural dynamics of molecular systems including nucleic acids has attracted attention in the context of gene regulation. Structure-function relationship is an important…

生物大分子 · 定量生物学 2021-11-23 Takeru Kameda , Akinori Awazu , Yuichi Togashi

Droplet formation has emerged as an essential concept for the spatiotemporal organisation of biomolecules in cells. However, classical descriptions of droplet dynamics based on passive liquid-liquid phase separation cannot capture the…

生物物理 · 物理学 2025-11-14 David Zwicker , Oliver W. Paulin , Cathelijne ter Burg

Radioactive molecules provide a powerful new platform in the search for new physics at energy scales complementary to high-energy particle colliders. By combining enhancements from nuclear properties with the sensitivity and control offered…

原子物理 · 物理学 2026-05-14 A. Jadbabaie , S. Ebadi , R. F. Garcia Ruiz , N. R. Hutzler , A. M. Jayich , J. T. Singh