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Due to inherent noise in intracellular networks cellular decisions can be random, so genetically identical cells can display different phenotypic behavior even in identical environments. Most previous work in understanding the…

分子网络 · 定量生物学 2015-06-15 Michael Assaf , Elijah Roberts , Zaida Luthey-Schulten , Nigel Goldenfeld

In this work, we study the generalizability of diffusion models by looking into the hidden properties of the learned score functions, which are essentially a series of deep denoisers trained on various noise levels. We observe that as…

机器学习 · 计算机科学 2024-12-03 Xiang Li , Yixiang Dai , Qing Qu

Recurrently connected neuron populations play key roles in sensory perception and memory storage across various brain regions. While these populations are often assumed to encode information through firing rates, this method becomes…

神经元与认知 · 定量生物学 2025-09-05 Mauricio Girardi-Schappo , Leonard Maler , André Longtin

Spike generation in neurons produces a temporal point process, whose statistics is governed by intrinsic phenomena and the external incoming inputs to be coded. In particular, spike-evoked adaptation currents support a slow temporal process…

神经元与认知 · 定量生物学 2016-10-31 Eugenio Urdapilleta

Predictive coding is a message-passing framework initially developed to model information processing in the brain, and now also topic of research in machine learning due to some interesting properties. One of such properties is the natural…

机器学习 · 计算机科学 2022-12-12 Billy Byiringiro , Tommaso Salvatori , Thomas Lukasiewicz

In the human brain, internal states are often correlated over time (due to local recurrence and other intrinsic circuit properties), punctuated by abrupt transitions. At first glance, temporal smoothness of internal states presents a…

机器学习 · 计算机科学 2023-05-24 Shima Rahimi Moghaddam , Fanjun Bu , Christopher J. Honey

In this paper, a novel learning-based Wyner-Ziv coding framework is considered under a distributed image transmission scenario, where the correlated source is only available at the receiver. Unlike other learnable frameworks, our approach…

信息论 · 计算机科学 2025-02-06 Yuxuan Shi , Shuo Shao , Yongpeng Wu , Wenjun Zhang , Merouane Debbah

While our understanding of the way single neurons process chromatic stimuli in the early visual pathway has advanced significantly in recent years, we do not yet know how these cells interact to form stable representations of hue. Drawing…

神经元与认知 · 定量生物学 2023-04-18 Zily Burstein , David D. Reid , Peter J. Thomas , Jack D. Cowan

Training a deep convolutional neural net typically starts with a random initialisation of all filters in all layers which severely reduces the forward signal and back-propagated error and leads to slow and sub-optimal training. Techniques…

计算机视觉与模式识别 · 计算机科学 2017-06-14 Brendan Ruff

Driven by the flexible manufacturing trend in the process control industry and the uncertain nature of chemical process models, this article aims to achieve offset-free tracking for a family of uncertain nonlinear systems (e.g., using…

系统与控制 · 电气工程与系统科学 2022-05-10 Lai Wei , Ryan McCloy , Jie Bao

The predictive power of neural networks often costs model interpretability. Several techniques have been developed for explaining model outputs in terms of input features; however, it is difficult to translate such interpretations into…

机器学习 · 计算机科学 2017-08-17 Benjamin J. Lengerich , Sandeep Konam , Eric P. Xing , Stephanie Rosenthal , Manuela Veloso

Neural responses are highly variable, and some portion of this variability arises from fluctuations in modulatory factors that alter their gain, such as adaptation, attention, arousal, expected or actual reward, emotion, and local metabolic…

神经元与认知 · 定量生物学 2015-07-08 Neil C. Rabinowitz , Robbe L. T. Goris , Johannes Ballé , Eero P. Simoncelli

This paper presents a new artificial neuron model capable of learning its receptive field in the topological domain of inputs. The model provides adaptive and differentiable local connectivity (plasticity) applicable to any domain. It…

神经与进化计算 · 计算机科学 2020-09-08 F. Boray Tek

Many membrane channels and receptors exhibit adaptive, or desensitized, response to a strong sustained input stimulus, often supported by protein activity-dependent inactivation. Adaptive response is thought to be related to various…

分子网络 · 定量生物学 2015-03-13 Tamar Friedlander , Naama Brenner

A model of sensory information processing is presented. The model assumes that learning of internal (hidden) generative models, which can predict the future and evaluate the precision of that prediction, is of central importance for…

神经与进化计算 · 计算机科学 2007-05-23 Andras Lorincz

Similar activity patterns may arise from model neural networks with distinct coupling properties and individual unit dynamics. These similar patterns may, however, respond differently to parameter variations and, specifically, to tuning of…

神经元与认知 · 定量生物学 2023-06-16 Zhuojun Yu , Jonathan E. Rubin , Peter J. Thomas

Learning in artificial neural networks usually relies on continuous, externally driven weight updates, in which parameters are modified at every step in response to incoming data, error signals or reward feedback. In this setting, routine…

神经元与认知 · 定量生物学 2026-05-13 Arturo Tozzi

In physical networks trained using supervised learning, physical parameters are adjusted to produce desired responses to inputs. An example is electrical contrastive local learning networks of nodes connected by edges that are resistors…

无序系统与神经网络 · 物理学 2024-12-30 Marcel Guzman , Felipe Martins , Menachem Stern , Andrea J. Liu

Stochastic integrate-and-fire (IF) neuron models have found widespread applications in computational neuroscience. Here we present results on the white-noise-driven perfect, leaky, and quadratic IF models, focusing on the spectral…

神经元与认知 · 定量生物学 2015-05-14 Rafael D. Vilela , Benjamin Lindner

The diversity of neuron models used in contemporary theoretical neuroscience to investigate specific properties of covariances raises the question how these models relate to each other. In particular it is hard to distinguish between…

神经元与认知 · 定量生物学 2022-05-17 Dmytro Grytskyy , Tom Tetzlaff , Markus Diesmann , Moritz Helias