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This paper presents the first, 15-PetaFLOP Deep Learning system for solving scientific pattern classification problems on contemporary HPC architectures. We develop supervised convolutional architectures for discriminating signals in…

The 70 kDa Heat Shock Proteins Hsp70 have several essential functions in living systems, such as protecting cells against protein aggregation, assisting protein folding, remodeling protein complexes and driving the translocation into…

生物大分子 · 定量生物学 2017-07-26 Basile Nguyen , David Hartich , Udo Seifert , Paolo De Los Rios

Protein conformational transitions, which are essential for function, may be driven either by entropy or enthalpy when molecular systems comprising solute and solvent molecules are the focus. Revealing thermodynamic origin of a given…

生物大分子 · 定量生物学 2015-05-04 Kai Wang , Shiyang Long , Zhiming Zhang , Lanru Liu , Qimeng Wang , Pu Tian

Antagonistic interactions in biological systems, which occur when one perturbation blunts the effect of another, are typically interpreted as evidence that the two perturbations impact the same cellular pathway or function. Yet, this…

Chemical disequilibrium in planetary atmospheres has been proposed as a generalized method for detecting life on exoplanets through remote spectroscopy. Among solar system planets with substantial atmospheres, the modern Earth has the…

地球与行星天体物理 · 物理学 2018-01-26 Joshua Krissansen-Totton , Stephanie Olson , David C. Catling

Spectral characterization of Super-Earth atmospheres for planets orbiting in the Habitable Zone of M-dwarf stars is a key focus in exoplanet science. A central challenge is to understand and predict the expected spectral signals of…

地球与行星天体物理 · 物理学 2015-06-15 J. L. Grenfell , S. Gebauer , M. Godolt , K. Palczynski , H. Rauer , J. Stock , P. v. Paris , R. Lehmann , F. Selsis

Warm Jupiters are ideal laboratories for testing the limitations of current tools for atmospheric studies. The cross-correlation technique is a commonly used method to investigate the atmospheres of close-in planets, leveraging their large…

地球与行星天体物理 · 物理学 2024-08-02 Bibiana Prinoth , Elyar Sedaghati , Julia V. Seidel , H. Jens Hoeijmakers , Rafael Brahm , Brian Thorsbro , Andrés Jordán

While high-resolution cross-correlation spectroscopy (HRCCS) techniques have proven effective at characterizing the atmospheres of transiting and non-transiting hot Jupiters, the limitations of these techniques are not well understood. We…

The close-in extrasolar giant planets (CEGPs) reside in irradiated environments much more intense than that of the giant planets in our solar system. The high UV irradiance strongly influences their photochemistry and the general current…

天体物理学 · 物理学 2009-11-10 Mao-Chang Liang , Sara Seager , Christopher D. Parkinson , Anthony Y. -T , . Lee , Yuk L. Yung

The atmospheric pressure-temperature profiles for transiting giant planets cross a range of chemical transitions. Here we show that the particular shape of these irradiated profiles for warm giant planets below 1300 K lead to striking…

The study of exoplanets at different evolutionary stages can shed light on their formation, migration, and evolution. The determination of exoplanet properties depends on the properties of their host stars. It is therefore important to…

Some atmospheric gases have been proposed as counter indicators to the presence of life on an exoplanet if remotely detectable at sufficient abundance (i.e., antibiosignatures), informing the search for biosignatures and potentially…

The ability to monitor nutrient and other environmental conditions with high sensitivity is crucial for cell growth and survival. Sensory adaptation allows a cell to recover its sensitivity after a transient response to a shift in the…

亚细胞过程 · 定量生物学 2016-01-07 Shou-Wen Wang , Yueheng Lan , Lei-Han Tang

A primary goal of characterizing exoplanet atmospheres is to constrain planetary bulk properties, such as their metallicity, C/O ratio, and intrinsic heat. However, there are significant uncertainties in many aspects of atmospheric physics,…

地球与行星天体物理 · 物理学 2024-10-23 Sagnick Mukherjee , Jonathan J. Fortney , Nicholas F. Wogan , David K. Sing , Kazumasa Ohno

We introduce ECCOplanets, an open-source Python code that simulates condensation in the protoplanetary disk. Our aim is to analyse how well a simplistic model can reproduce the main characteristics of rocky planet formation. For this…

地球与行星天体物理 · 物理学 2023-08-09 Anina Timmermann , Yutong Shan , Ansgar Reiners , Andreas Pack

UV absorption cross sections are an essential ingredient of photochemical atmosphere models. Exoplanet searches have unveiled a large population of short-period objects with hot atmospheres, very different from what we find in our solar…

Recent observations of the Earth's exosphere revealed the presence of an extended hydrogenic component that could reach distances beyond 40 planetary radii. Detection of similar extended exospheres around Earth-like exoplanets could reveal…

地球与行星天体物理 · 物理学 2023-03-06 Ada Canet , Ana Inés Gómez de Castro

We present an analysis of 40 cool helium-rich white dwarfs found in the Hamburg/ESO survey. They were selected for follow-up spectroscopy because of their U-B colour below -0.18, the absence of strong absorption lines, and a continuum shape…

天体物理学 · 物理学 2007-05-23 S. Friedrich , D. Koester , N. Christlieb , D. Reimers , L. Wisotzki

Finding life on other worlds is a fascinating area of astrobiology and planetary sciences. Presently, over 3500 exoplanets, representing a very wide range of physical and chemical environments, are known. Tardigrades (water bears) are…

科普物理 · 物理学 2018-10-08 Madhu Kashyap Jagadeesh , Milena Roszkowska , Lukasz Kaczmarek

The problem is considered of optimizing discrete parameters in the presence of constraints. We use the stochastic sigmoid with temperature and put forward the new adaptive gradient method CONGA. The search for an optimal solution is carried…

最优化与控制 · 数学 2024-01-17 Andrei Beinarovich , Sergey Stepanov , Alexander Zaslavsky