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An automatic evidential segmentation method based on Dempster-Shafer theory and deep learning is proposed to segment lymphomas from three-dimensional Positron Emission Tomography (PET) and Computed Tomography (CT) images. The architecture…

计算机视觉与模式识别 · 计算机科学 2022-11-21 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

Complex biological systems have been successfully modeled by biochemical and genetic interaction networks, typically gathered from high-throughput (HTP) data. These networks can be used to infer functional relationships between genes or…

分子网络 · 定量生物学 2015-04-13 Hyunghoon Cho , Bonnie Berger , Jian Peng

The huge amount of data acquired by high-throughput sequencing requires data reduction for effective analysis. Here we give a clustering algorithm for genome-wide open chromatin data using a new data reduction method. This method regards…

Independent Component Analysis (ICA) aims to recover independent latent variables from observed mixtures thereof. Causal Representation Learning (CRL) aims instead to infer causally related (thus often statistically dependent) latent…

The complexities inherent to leukemia, multifaceted cancer affecting white blood cells, pose considerable diagnostic and treatment challenges, primarily due to reliance on laborious morphological analyses and expert judgment that are…

We present an applied study in cancer genomics for integrating data and inferences from laboratory experiments on cancer cell lines with observational data obtained from human breast cancer studies. The biological focus is on improving…

应用统计 · 统计学 2010-10-07 Daniel Merl , Julia Ling-Yu Chen , Jen-Tsan Chi , Mike West

Clustering techniques offer a powerful framework for analyzing complex flow dynamics and reducing computational costs in large-scale simulations. In this work, we propose a novel clustering-based approach using Vector Quantization Principal…

流体动力学 · 物理学 2026-03-05 Juan Angel Martin , Eva Muñoz , Himanshu Dave , Alessandro Parente , Soledad Le Clainche

Purpose: This study examines the core traits of image-to-image translation (I2I) networks, focusing on their effectiveness and adaptability in everyday clinical settings. Methods: We have analyzed data from 794 patients diagnosed with…

图像与视频处理 · 电气工程与系统科学 2025-07-22 Mohammad R. Salmanpour , Amin Mousavi , Yixi Xu , William B Weeks , Ilker Hacihaliloglu

Principal component analysis (PCA) is a tool to capture factors that explain variation in data. Across domains, data are now collected across multiple contexts (for example, individuals with different diseases, cells of different types, or…

机器学习 · 统计学 2026-01-22 Kexin Wang , Salil Bhate , João M. Pereira , Joe Kileel , Matylda Figlerowicz , Anna Seigal

Recognizing specific events in medical data requires trained personnel. To aid the classification, machine learning algorithms can be applied. In this context, medical records are usually high-dimensional, although a lower dimension can…

信号处理 · 电气工程与系统科学 2025-02-19 Annika Stiehl , Stefan Geißelsöder , Nicole Ille , Fabienne Anselstetter , Harald Bornfleth , Christian Uhl

Topological data analysis (TDA) is an active field of mathematics for quantifying shape in complex data. Standard methods in TDA such as persistent homology (PH) are typically focused on the analysis of data consisting of a single entity…

The objectives of this "perspective" paper are to review some recent advances in sparse feature selection for regression and classification, as well as compressed sensing, and to discuss how these might be used to develop tools to advance…

定量方法 · 定量生物学 2015-06-18 Mathukumalli Vidyasagar

We introduce a new image cytometer design for detection of very small particulate and demonstrate its capability in water analysis. The device is a compact microscope composed of off the shelf components, such as a light emitting diode…

光学 · 物理学 2016-02-17 Juan Miguel Pérez , Marc Jofre , Pedro Martínez , Valerio Pruneri

The cancer prognosis on gigapixel Whole-Slide Images (WSIs) has always been a challenging task. To further enhance WSI visual representations, existing methods have explored image pyramids, instead of single-resolution images, in WSIs. In…

图像与视频处理 · 电气工程与系统科学 2023-05-15 Pei Liu , Bo Fu , Feng Ye , Rui Yang , Bin Xu , Luping Ji

Biomarker measurements obtained by blood sampling are often used as a non-invasive means of monitoring tumour progression in cancer patients. Diseases evolve dynamically over time, and studying longitudinal observations of specific…

应用统计 · 统计学 2025-03-14 Alice Cleynen , Benoîte de Saporta , Amélie Vernay

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

计算机视觉与模式识别 · 计算机科学 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Image Coding for Machines (ICM) is becoming more important as research in computer vision progresses. ICM is a vital research field that pursues the use of images for image recognition models, facilitating efficient image transmission and…

计算机视觉与模式识别 · 计算机科学 2024-10-17 Takahiro Shindo , Taiju Watanabe , Yui Tatsumi , Hiroshi Watanabe

Optical flow estimation is a fundamental and long-standing visual task. In this work, we present a novel method, dubbed HMAFlow, to improve optical flow estimation in challenging scenes, particularly those involving small objects. The…

计算机视觉与模式识别 · 计算机科学 2024-11-18 Dianbo Ma , Kousuke Imamura , Ziyan Gao , Xiangjie Wang , Satoshi Yamane

Background: Cancers are highly heterogeneous with different subtypes. These subtypes often possess different genetic variants, present different pathological phenotypes, and most importantly, show various clinical outcomes such as varied…

图形学 · 计算机科学 2014-07-09 Hao Ding , Chao Wang , Kun Huang , Raghu Machiraju

Predictive modeling from high-dimensional genomic data is often preceded by a dimension reduction step, such as principal components analysis (PCA). However, the application of PCA is not straightforward for multi-source data, wherein…

定量方法 · 定量生物学 2017-07-19 Adam Kaplan , Eric F. Lock