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Branched actin networks at the leading edge of a crawling cell evolve via protein-regulated processes such as polymerization, depolymerization, capping, branching, and severing. A formulation of these processes is presented and analyzed to…

软凝聚态物质 · 物理学 2009-11-13 Ajay Gopinathan , Kun-Chun Lee , J. M. Schwarz , Andrea J. Liu

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

神经元与认知 · 定量生物学 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

The links between optimal control of dynamical systems and neural networks have proved beneficial both from a theoretical and from a practical point of view. Several researchers have exploited these links to investigate the stability of…

最优化与控制 · 数学 2019-02-08 Panos Parpas , Corey Muir

We develop a progressive training approach for neural networks which adaptively grows the network structure by splitting existing neurons to multiple off-springs. By leveraging a functional steepest descent idea, we derive a simple…

机器学习 · 计算机科学 2019-11-06 Qiang Liu , Lemeng Wu , Dilin Wang

This article highlights specific features of biological neurons and their dendritic trees, whose adoption may help advance artificial neural networks used in various machine learning applications. Advancements could take the form of…

神经元与认知 · 定量生物学 2021-06-15 Spyridon Chavlis , Panayiota Poirazi

Although inspired by neuronal systems in the brain, artificial neural networks generally employ point-neurons, which offer far less computational complexity than their biological counterparts. Neurons have dendritic arbors that connect to…

新兴技术 · 计算机科学 2025-10-22 A N M Nafiul Islam , Xuezhong Niu , Jiahui Duan , Shubham Kumar , Kai Ni , Abhronil Sengupta

Neurons are spatially extended structures that receive and process inputs on their dendrites. It is generally accepted that neuronal computations arise from the active integration of synaptic inputs along a dendrite between the input…

神经元与认知 · 定量生物学 2013-09-11 Willem A. M. Wybo , Klaus M. Stiefel , Benjamin Torben-Nielsen

The structure and quantitative composition of the cerebral cortex are interrelated with its computational capacity. Empirical data analyzed here indicate a certain hierarchy in local cortical composition. Specifically, neural wire, i.e.,…

神经元与认知 · 定量生物学 2015-10-29 Jan Karbowski

Developmental plasticity plays a prominent role in shaping the brain's structure during ongoing learning in response to dynamically changing environments. However, the existing network compression methods for deep artificial neural networks…

神经与进化计算 · 计算机科学 2024-10-29 Bing Han , Feifei Zhao , Yi Zeng , Guobin Shen

While much of the work in the design of convolutional networks over the last five years has revolved around the empirical investigation of the importance of depth, filter sizes, and number of feature channels, recent studies have shown that…

机器学习 · 计算机科学 2017-12-08 Karim Ahmed , Lorenzo Torresani

Deep Neural Networks (DNN) have achieved human level performance in many image analytics tasks but DNNs are mostly deployed to GPU platforms that consume a considerable amount of power. Brain-inspired spiking neuromorphic chips consume low…

神经与进化计算 · 计算机科学 2016-05-26 Antonio Jimeno Yepes , Jianbin Tang

The relative importance of the intrinsic and extrinsic factors determining the variety of geometric shapes exhibited by dendritic trees remains unclear. This question was addressed by developing a model of the growth of dendritic trees…

神经元与认知 · 定量生物学 2007-05-23 Artur Luczak

Spontaneous neuronal activity is a ubiquitous feature of cortex. Its spatiotemporal organization reflects past input and modulates future network output. Here we study whether a particular type of spontaneous activity is generated by a…

神经元与认知 · 定量生物学 2009-11-09 Woodrow L. Shew , Hongdian Yang , Thomas Petermann , Rajarshi Roy , Dietmar Plenz

During neurodevelopment, neuronal axons navigate through the extracellular environment, guided by various cues to establish connections with distant target cells. Among other factors, axon trajectories are influenced by heterogeneities in…

生物物理 · 物理学 2025-09-09 Christoforos Kassianides , Alain Goriely , Hadrien Oliveri

Deep learning has led to significant advances in artificial intelligence, in part, by adopting strategies motivated by neurophysiology. However, it is unclear whether deep learning could occur in the real brain. Here, we show that a deep…

神经元与认知 · 定量生物学 2017-04-11 Jordan Guergiuev , Timothy P. Lillicrap , Blake A. Richards

Migrating cells exhibit various motility patterns, resulting from different migration mechanisms, cell properties, or cell-environment interactions. The complexity of cell dynamics is reflected, e.g., in the diversity of the observed forms…

生物物理 · 物理学 2023-07-07 M. Reza Shaebani , Matthieu Piel , Franziska Lautenschläger

Dendrites are crucial structures for computation of an individual neuron. It has been shown that the dynamics of a biological neuron with dendrites can be approximated by artificial neural networks (ANN) with deep structure. However, it…

神经元与认知 · 定量生物学 2023-05-23 Jingyang Ma , Songting Li , Douglas Zhou

Neuronal dendrites form densely branched tree architectures through which mitochondria must be distributed to supply the cell's energetic needs. Dendritic mitochondria circulate through the tree, undergoing fusion and fission to form…

生物物理 · 物理学 2024-05-09 Mario Hidalgo-Soria , Elena F. Koslover

Artificial neural networks (ANNs) are at the core of most Deep learning (DL) algorithms that successfully tackle complex problems like image recognition, autonomous driving, and natural language processing. However, unlike biological brains…

神经与进化计算 · 计算机科学 2024-09-16 Spyridon Chavlis , Panayiota Poirazi

Sophisticated machine learning struggles to transition onto battery-operated devices due to the high-power consumption of neural networks. Researchers have turned to neuromorphic engineering, inspired by biological neural networks, for more…

神经与进化计算 · 计算机科学 2023-11-23 Daniel John Mannion