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Deducing an underlying multi-substate on-off kinetic scheme (KS) from the statistical properties of a two-state trajectory is the aim from many experiments in biophysics and chemistry, such as, ion channel recordings, enzymatic activity and…

定量方法 · 定量生物学 2011-04-11 Ophir Flomenbom

Single molecule data made of on and off events are ubiquitous. Famous examples include enzyme turnover, probed via fluorescence, and opening and closing of ion-channel, probed via the flux of ions. The data reflects the dynamics in the…

定量方法 · 定量生物学 2010-08-16 Ophir Flomenbom , Robert J. Silbey

Trajectories of a signal that fluctuates between two states which originate from single molecule activities have become ubiquitous. Common examples are trajectories of ionic flux through individual membrane-channels, and of photon counts…

定量方法 · 定量生物学 2007-05-23 Ophir Flomenbom , J. Klafter

We consider offline reinforcement learning (RL) in $H$-horizon Markov decision processes (MDPs) under the linear $q^\pi$-realizability assumption, where the action-value function of every policy is linear with respect to a given…

机器学习 · 计算机科学 2024-05-28 Volodymyr Tkachuk , Gellért Weisz , Csaba Szepesvári

Dimension reduction is often needed in the area of data mining. The goal of these methods is to map the given high-dimensional data into a low-dimensional space preserving certain properties of the initial data. There are two kinds of…

数值分析 · 数学 2015-03-23 Yanlai Chen

The problem of determining which nucleotides of an RNA sequence are paired or unpaired in the secondary structure of an RNA, which we call RNA state inference, can be studied by different machine learning techniques. Successful state…

生物大分子 · 定量生物学 2024-07-09 Devin Willmott , David Murrugarra , Qiang Ye

Direct Statistical Simulation (DSS) solves the equations of motion for the statistics of turbulent flows in place of the traditional route of accumulating statistics by Direct Numerical Simulation (DNS). That low-order statistics usually…

流体动力学 · 物理学 2020-07-15 Altan Allawala , S. M. Tobias , J. B. Marston

Learning complex trajectories from demonstrations in robotic tasks has been effectively addressed through the utilization of Dynamical Systems (DS). State-of-the-art DS learning methods ensure stability of the generated trajectories;…

机器人学 · 计算机科学 2024-12-10 Andreas Sochopoulos , Michael Gienger , Sethu Vijayakumar

Dynamic mode decomposition (DMD) is a recently developed tool for the analysis of the behavior of complex dynamical systems. In this paper, we will propose an extension of DMD that exploits low-rank tensor decompositions of potentially…

数值分析 · 数学 2019-08-14 Stefan Klus , Patrick Gelß , Sebastian Peitz , Christof Schütte

Pushdown systems (PDSs) and recursive state machines (RSMs), which are linearly equivalent, are standard models for interprocedural analysis. Yet RSMs are more convenient as they (a) explicitly model function calls and returns, and (b)…

编程语言 · 计算机科学 2020-01-13 Krishnendu Chatterjee , Bernhard Kragl , Samarth Mishra , Andreas Pavlogiannis

Hamilton Jacobi (HJ) Reachability is a formal verification tool widely used in robotic safety analysis. Given a target set as unsafe states, a dynamical system is guaranteed not to enter the target under the worst-case disturbance if it…

最优化与控制 · 数学 2020-03-18 Anjian Li , Mo Chen

This work studies the linear approximation of high-dimensional dynamical systems using low-rank dynamic mode decomposition (DMD). Searching this approximation in a data-driven approach is formalised as attempting to solve a low-rank…

机器学习 · 统计学 2021-08-23 Patrick Héas , Cédric Herzet

MATLAB(R) releases over the last 3 years have witnessed a continuing growth in the dynamic modeling capabilities offered by the System Identification Toolbox(TM). The emphasis has been on integrating deep learning architectures and training…

机器学习 · 计算机科学 2024-09-13 Tianyu Dai , Khaled Aljanaideh , Rong Chen , Rajiv Singh , Alec Stothert , Lennart Ljung

Dynamic substructuring (DS) methods encompass a range of techniques to decompose large structural systems into multiple coupled subsystems. This decomposition has the principle benefit of reducing computational time for dynamic simulation…

计算工程、金融与科学 · 计算机科学 2020-07-01 Thomas Simpson , Dimitrios Giagopoulos , Vasilis Dertimanis , Eleni Chatzi

Leveraging recent work on data-driven methods for constructing a finite state space Markov process from dynamical systems, we address two problems for obtaining further reduced statistical representations. The first problem is to extract…

混沌动力学 · 物理学 2024-05-14 Ludovico Theo Giorgini , Andre N. Souza , Peter J. Schmid

This contribution proposes novel data-driven surrogate modeling approaches for parameterized parabolic PDEs, where the parameter dependence can be split into two parts with different decay behavior of the Kolmogorov $N$-width. Such problems…

数值分析 · 数学 2026-04-27 Dawid Kotowski , Mario Ohlberger

Data-dependent metrics are powerful tools for learning the underlying structure of high-dimensional data. This article develops and analyzes a data-dependent metric known as diffusion state distance (DSD), which compares points using a…

机器学习 · 统计学 2020-03-10 Lenore Cowen , Kapil Devkota , Xiaozhe Hu , James M. Murphy , Kaiyi Wu

Respondent-driven sampling (RDS) is a link-tracing sampling method that is especially suitable for sampling hidden populations. RDS combines an efficient snowball-type sampling scheme with inferential procedures that yield unbiased…

统计方法学 · 统计学 2016-03-15 Jens Malmros , Luis E. C. Rocha

This paper presents a quasi-deterministic ray tracing (QD-RT) method for analyzing the propagation of electromagnetic waves in street canyons. The method uses a statistical bistatic distribution to model the Radar Cross Section (RCS) of…

网络与互联网体系结构 · 计算机科学 2025-03-18 Javad Ebrahimizadeh , Evgenii Vinogradov , Guy A. E. Vandenbosch

We propose a discrete transition-based reweighting analysis method (dTRAM) for analyzing configuration-space-discretized simulation trajectories produced at different thermodynamic states (temperatures, Hamiltonians, etc.) dTRAM provides…

数据分析、统计与概率 · 物理学 2015-06-23 Hao Wu , Antonia S. J. S. Mey , Edina Rosta , Frank Noé
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