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In this paper we present continuous age- and space-structured models and numerical computations of Proteus mirabilis swarm-colony development. We base the mathematical representation of the cell-cycle dynamics of Proteus mirabilis on those…

细胞行为 · 定量生物学 2023-02-14 Bruce P. Ayati

We prove a global existence result for a model describing the swarming phenomenon of the bacterium Proteus mirabilis. The model consists of an ordinary differential equation coupled with an age-structured equation involving nonlinear…

偏微分方程分析 · 数学 2008-09-09 Philippe Laurençot , Christoph Walker

We present models and computational results which indicate that the spatial and temporal regularity seen in Proteus mirabilis swarm-colony development is largely an expression of a sharp age of dedifferentiation in the cell cycle from…

细胞行为 · 定量生物学 2023-02-14 Bruce P. Ayati

The periodic swarming of bacteria is one of the simplest examples for pattern formation produced by the self-organized collective behavior of a large number of organisms. In the spectacular colonies of Proteus mirabilis (the most common…

生物物理 · 物理学 2016-09-08 Andras Czirok , Mitsugu Matsushita , Tamas Vicsek

In this paper we explain the biophysical principles which, according to us, govern the Proteus mirabilis swarm phenomenon. Then, we translate this explanation into a mathematical model, essentially based on partial differential equations.…

偏微分方程分析 · 数学 2008-10-23 Emmanuel Frenod , Olivier Sire

In this paper we present a modification of the usual Proteus mirabilis swarm model. For the obtained model (which is a two phase model with a non-linear diffusion term containing memory) we set up a collection of a priori estimates. Those…

泛函分析 · 数学 2007-05-23 Emmanuel Frenod

The enteric bacterium Proteus mirabilis, which is a pathogen that forms biofilms in vivo, can swarm over hard surfaces and form concentric ring patterns in colonies. Colony formation involves two distinct cell types: swarmer cells that…

种群与进化 · 定量生物学 2015-05-28 Chuan Xue , Elena O. Budrene , Hans G. Othmer

A diffusion-reaction model for the growth of bacterial colonies is presented. The often observed cooperative behavior developed by bacteria which increases their motility in adverse growth conditions is here introduced as a nonlinear…

凝聚态物理 · 物理学 2009-10-31 A. M. Lacasta , I. R. Cantalapiedra , C. E. Auguet , A. Penaranda , L. Ramirez-Piscina

The field of active matter explores the behaviors of self propelled agents out of equilibrium, with active suspensions, such as swimming bacteria in solutions, serving as impactful models. These systems exhibit spatio-temporal patterns akin…

软凝聚态物质 · 物理学 2025-08-26 Pratikshya Jena , Shradha Mishra

Various bacterial strains (e.g. strains belonging to the genera Bacillus, Paenibacillus, Serratia and Salmonella) exhibit colonial branching patterns during growth on poor semi-solid substrates. These patterns reflect the bacterial…

凝聚态物理 · 物理学 2009-10-31 Yonathan Kozlovsky , Inon Cohen , Ido Golding , Eshel Ben-Jacob

Biological systems are promising substrates for computation because they naturally process environmental information through complex internal dynamics. In this study, we investigate whether bacterial metabolic models can act as physical…

新兴技术 · 计算机科学 2026-04-23 Laura Alonso Bartolomé , Jean-Loup Faulon , Xavier Hinaut

Motivated by recent research of aging in E. coli, we explore the effects of aging on bacterial fitness. The disposable soma theory of aging was developed to explain how differences in lifespans and aging rates could be linked to life…

种群与进化 · 定量生物学 2007-05-23 Leah R. Johnson , Marc Mangel

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

生物物理 · 物理学 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

统计力学 · 物理学 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

种群与进化 · 定量生物学 2007-05-23 Michele Bezzi , Andrea Ciliberto

We present a mathematical model based on a system of partial differential equations (PDEs) with cross-diffusion and reaction terms to describe ecological interactions between multiple bacterial species and substrates within microaggregates,…

种群与进化 · 定量生物学 2025-12-16 Viktoria Freingruber , Rebeca Gonzalez-Cabaleiro , Havva Yoldaş

We study non-equilibrium bacterial colony growth using a geometry-first, time-resolved analysis of morphology. From time-lapse microscopy data, we track the coupled evolution of area, perimeter, and boundary-sensitive shape descriptors…

软凝聚态物质 · 物理学 2026-02-06 Benjamin Evert Himberg , Sanghita Sengupta

Motivated by structured parasite populations in aquaculture we consider a class of size-structured population models, where individuals may be recruited into the population with distributed states at birth. The mathematical model which…

偏微分方程分析 · 数学 2019-03-25 Jozsef Z. Farkas , Darren Green , Peter Hinow

Segregation of populations is a key question in evolution theory. One important aspect is the relation between spatial organization and the population's composition. Here we study a specific example -- sectors in expanding bacterial…

凝聚态物理 · 物理学 2009-10-31 Ido Golding , Inon Cohen , Eshel Ben-Jacob

Myxobacteria are social bacteria, that can glide in 2D and form counter-propagating, interacting waves. Here we present a novel age-structured, continuous macroscopic model for the movement of myxobacteria. The derivation is based on…

细胞行为 · 定量生物学 2018-04-06 Pierre Degond , Angelika Manhart , Hui Yu
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