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Kinetic models of biochemical systems used in the modern literature often contain hundreds or even thousands of variables. While these models are convenient for detailed simulations, their size is often an obstacle to deriving mechanistic…

分子网络 · 定量生物学 2021-06-29 Gleb Pogudin , Xingjian Zhang

By any account, the 1998 proof of the Kepler conjecture is complex. The thesis underlying this article is that the proof is complex because it is highly under-automated. Throughout that proof, manual procedures are used where automated ones…

度量几何 · 数学 2007-05-23 Thomas C. Hales

The potential for neuromorphic computing to provide intrinsic fault tolerance has long been speculated, but the brain's robustness in neuromorphic applications has yet to be demonstrated. Here, we show that a previously described, natively…

神经与进化计算 · 计算机科学 2026-03-12 Bradley H. Theilman , James B. Aimone

A known first order method to find a feasible solution to a conic problem is an adapted von Neumann algorithm. We improve the distance reduction step there by projecting onto the convex hull of previously generated points using a primal…

最优化与控制 · 数学 2014-08-15 C. H. Jeffrey Pang

This paper studies the robustness of observability of a linear time-invariant system under sensor failures from a computational perspective. To be precise, the problem of determining the minimum number of sensors whose removal can destroy…

最优化与控制 · 数学 2023-07-18 Yuan Zhang , Yuanqing Xia , Kun Liu

There are several forms of irreducibility in computing systems, ranging from undecidability to intractability to nonlinearity. This paper is an exploration of the conceptual issues that have arisen in the course of investigating speed-up…

计算复杂性 · 计算机科学 2011-06-24 Hector Zenil , Fernando Soler-Toscano , Joost J. Joosten

Many high-dimensional optimisation problems exhibit rich geometric structures in their set of minimisers, often forming smooth manifolds due to over-parametrisation or symmetries. When this structure is known, at least locally, it can be…

最优化与控制 · 数学 2025-10-27 Evan Markou , Thalaiyasingam Ajanthan , Stephen Gould

In this paper, an idea to solve nonlinear equations is presented. During the solution of any problem with Newton's Method, it might happen that some of the unknowns satisfy the convergence criteria where the others fail. The convergence…

数学软件 · 计算机科学 2012-03-15 Erhan Turan , Ali Ecder

Inverse optimization refers to the inference of unknown parameters of an optimization problem based on knowledge of its optimal solutions. This paper considers inverse optimization in the setting where measurements of the optimal solutions…

最优化与控制 · 数学 2017-12-27 Anil Aswani , Zuo-Jun Max Shen , Auyon Siddiq

An approach to amputation, the process of introducing missing values to a complete dataset, is presented. It allows to construct missingness indicators in a flexible and principled way via copulas and Bernoulli margins and to incorporate…

应用统计 · 统计学 2025-07-28 Marius Hofert , James Jackson , Niels Hagenbuch

Methods for the reduction of the complexity of computational problems are presented, as well as their connections to renormalization, scaling, and irreversible statistical mechanics. Several statistically stationary cases are analyzed; for…

数值分析 · 数学 2007-05-23 Alexandre J. Chorin , Panagiotis Stinis

This paper shows that, if we could examine the entire history of a hidden variable, then we could efficiently solve problems that are believed to be intractable even for quantum computers. In particular, under any hidden-variable theory…

量子物理 · 物理学 2007-05-23 Scott Aaronson

In this work numerical methods for solving Einstein's equations are developed and applied to the study of inhomogeneous cosmological models. A two-dimensional computer code is described which implements two advanced numerical methods:…

广义相对论与量子宇宙学 · 物理学 2007-05-23 Simon D. Hern

Neural Networks (NNs) can provide major empirical performance improvements for robotic systems, but they also introduce challenges in formally analyzing those systems' safety properties. In particular, this work focuses on estimating the…

系统与控制 · 电气工程与系统科学 2021-05-26 Michael Everett , Golnaz Habibi , Jonathan P. How

Numerical solutions to Newton's equations of motion for chaotic self gravitating systems of more than 2 bodies are often regarded to be irreversible. This is due to the exponential growth of errors introduced by the integration scheme and…

天体物理仪器与方法 · 物理学 2018-03-14 Simon Portegies Zwart , Tjarda Boekholt

In inverse problems we aim to reconstruct some underlying signal of interest from potentially corrupted and often ill-posed measurements. Classical optimization-based techniques proceed by optimizing a data consistency metric together with…

图像与视频处理 · 电气工程与系统科学 2022-10-17 Peimeng Guan , Jihui Jin , Justin Romberg , Mark A. Davenport

In this paper we take a quasi-Newton approach to nonlinear eigenvalue problems (NEPs) of the type $M(\lambda)v=0$, where $M:\mathbb{C}\rightarrow\mathbb{C}^{n\times n}$ is a holomorphic function. We investigate which types of approximations…

数值分析 · 数学 2017-03-01 Elias Jarlebring , Antti Koskela , Giampaolo Mele

In this work, we study several variants of matrix reduction via Gaussian elimination that try to keep the reduced matrix sparse. The motivation comes from the growing field of topological data analysis where matrix reduction is the major…

计算几何 · 计算机科学 2024-06-14 Ulrich Bauer , Talha Bin Masood , Barbara Giunti , Guillaume Houry , Michael Kerber , Abhishek Rathod

Slow running or straggler tasks can significantly reduce computation speed in distributed computation. Recently, coding-theory-inspired approaches have been applied to mitigate the effect of straggling, through embedding redundancy in…

机器学习 · 统计学 2018-01-24 Can Karakus , Yifan Sun , Suhas Diggavi , Wotao Yin

Nonnegative (linear) least square problems are a fundamental class of problems that is well-studied in statistical learning and for which solvers have been implemented in many of the standard programming languages used within the machine…

最优化与控制 · 数学 2022-03-09 Jelena Diakonikolas , Chenghui Li , Swati Padmanabhan , Chaobing Song
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