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This paper presents a probabilistic approach for DNA sequence analysis. A DNA sequence consists of an arrangement of the four nucleotides A, C, T and G and different representation schemes are presented according to a probability measure…

定量方法 · 定量生物学 2010-02-12 Amrita Priyam , B. M. Karan , G. Sahoo

The programmable assembly of DNA strands is a promising tool for building tailored bottom-up nanostructures. Here, we present a plasmonic nanosystem obtained by the base-pairing mediated aggregation of gold nanoparticles (NPs) which are…

应用物理 · 物理学 2019-12-03 D. Caprara , F. Ripanti , A. Capocefalo , A. Sarra , F. Brasili , C. Petrillo , C. Fasolato , P. Postorino

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (i.e. rarely accessed), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

图像与视频处理 · 电气工程与系统科学 2023-05-11 Xavier Pic , Eva Gil San Antonio , Melpomeni Dimopoulou , Marc Antonini

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

其他定量生物学 · 定量生物学 2014-03-12 Jian-Jun Shu , Li Shan Ouw

Next Generation Sequencing (NGS), a recently evolved technology, have served a lot in the research and development sector of our society. This novel approach is a newbie and has critical advantages over the traditional Capillary…

基因组学 · 定量生物学 2020-05-01 Khalid Raza , Sabahuddin Ahmad

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

定量方法 · 定量生物学 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

The purpose of this work is to extend the Geant4-DNA Monte Carlo toolkit to include electron interactions with the four DNA bases using a set of cross sections recently implemented in Geant-DNA CPA100 models and available for liquid water.…

Proteins are arguably the most important class of biomarkers for health diagnostic purposes. Label-free solid-state nanopore sensing is a versatile technique for sensing and analysing biomolecules such as proteins at single-molecule level.…

Molecular electronics and other technologies whose components comprise individual molecules have been pursued for half a century because the molecular scale represents the limit of miniaturisation of objects whose structure is tuneable for…

Due to its longevity and enormous information density, DNA is an attractive medium for archival data storage. Thanks to rapid technological advances, DNA storage is becoming practically feasible, as demonstrated by a number of experimental…

信息论 · 计算机科学 2022-11-11 Ilan Shomorony , Reinhard Heckel

In this work, we model the zero-bias conductance for the four different DNA strands that were used in conductance measurement experiment [A. K. Mahapatro, K. J. Jeong, G. U. Lee, and D. B. Janes, Nanotechnology 18, 195202 (2007)]. Our…

生物物理 · 物理学 2013-02-06 Jianqing Qi , Neranjan Edirisinghe , M. Golam Rabbani , M. P. Anantram

DNA data storage is rapidly emerging as a promising solution for long-term data archiving, largely due to its exceptional durability. However, the synthesis of DNA strands remains a significant bottleneck in terms of cost and speed. To…

其他计算机科学 · 计算机科学 2025-07-11 Parv Agarwal , Nimesh Pinnamaneni , Thomas Heinis

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

信息论 · 计算机科学 2025-04-22 Ruiying Cao , Xin Chen

The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies and biological features inherent in DNA. In this work, we…

计算工程、金融与科学 · 计算机科学 2026-03-09 Qirong Yang , Yucheng Guo , Zicheng Liu , Yujie Yang , Qijin Yin , Siyuan Li , Shaomin Ji , Linlin Chao , Xiaoming Zhang , Stan Z. Li

In this work we numerically calculate the electric current through three kinds of DNA sequences (telomeric, \lambda-DNA, and p53-DNA) described by different heuristic models. A bias voltage is applied between two zig-zag edged graphene…

介观与纳米尺度物理 · 物理学 2012-10-02 Carlos J. Páez , Peter A. Schulz , Neil Wilson , Rudolf A. Römer

This paper presents a novel DNA sequences alignment method based on inverted index. Now most large scale information retrieval system are all use inverted index as the basic data structure. But its application in DNA sequence alignment is…

基因组学 · 定量生物学 2013-07-02 Wang Liang , Zhao KaiYong

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single- and few-atom thick layers of 2D materials beyond graphene, and also that these materials can exhibit fascinating and…

介观与纳米尺度物理 · 物理学 2022-01-19 Benjamin O. Tayo

This paper studies two problems that are motivated by the novel recent approach of composite DNA that takes advantage of the DNA synthesis property which generates a huge number of copies for every synthesized strand. Under this paradigm,…

信息论 · 计算机科学 2025-05-15 Tomer Cohen , Eitan Yaakobi

Sequencing by Emergence (SEQE) is a new single-molecule nucleic acid (DNA/RNA) sequencing technology that estimates sequence as an emergent property of the binding and localization of a repertoire of short oligonucleotide probes. SEQE…

基因组学 · 定量生物学 2021-08-04 Nicholas Boyd , Samuel Woodhouse , Kalim Mir

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

硬件体系结构 · 计算机科学 2021-11-04 Damla Senol Cali