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We analyse a collection of empirical networks in a wide spectrum of disciplines and show that strong non-normality is ubiquitous in network science. Dynamical processes evolving on non-normal networks exhibit a peculiar behaviour, as…

适应与自组织系统 · 物理学 2018-11-09 Malbor Asllani , Renaud Lambiotte , Timoteo Carletti

Geometric and structural constraints greatly restrict the selection of folds adapted by protein backbones, and yet, folded proteins show an astounding diversity in functionality. For structure to have any bearing on function, it is thus…

生物物理 · 物理学 2010-04-20 Brinda K. V. , Saraswathi Vishveshwara , Smitha Vishveshwara

In this review, we give an introduction to the structural and functional properties of the biological networks. We focus on three major themes: topology of complex biological networks like the metabolic and protein-protein interaction…

凝聚态物理 · 物理学 2007-05-23 Indrani Bose

Given observations of a physical system, identifying the underlying non-linear governing equation is a fundamental task, necessary both for gaining understanding and generating deterministic future predictions. Of most practical relevance…

数值分析 · 数学 2020-03-02 A. Goeßmann , M. Götte , I. Roth , R. Sweke , G. Kutyniok , J. Eisert

We show that a neural network originally designed for language processing can learn the dynamical rules of a stochastic system by observation of a single dynamical trajectory of the system, and can accurately predict its emergent behavior…

统计力学 · 物理学 2022-02-18 Corneel Casert , Isaac Tamblyn , Stephen Whitelam

Euler's elastica is a classical model of flexible slender structures, relevant in many industrial applications. Static equilibrium equations can be derived via a variational principle. The accurate approximation of solutions of this problem…

The field of optimal design of linear elastic structures has seen many exciting successes that resulted in new architected materials and structural designs. With the availability of cloud computing, including high-performance computing,…

计算工程、金融与科学 · 计算机科学 2021-02-09 Diab W. Abueidda , Seid Koric , Nahil A. Sobh

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

生物物理 · 物理学 2015-05-13 Sitabhra Sinha

Real-world networks in technology, engineering and biology often exhibit dynamics that cannot be adequately reproduced using network models given by smooth dynamical systems and a fixed network topology. Asynchronous networks give a…

动力系统 · 数学 2017-02-07 Christian Bick , Michael Field

Modularity structures are common in various social and biological networks. However, its dynamical origin remains an open question. In this work, we set up a dynamical model describing the evolution of a social network. Based on the…

物理与社会 · 物理学 2011-08-19 Menghui Li , Shuguang Guan , Choy-Heng Lai

The network paradigm is increasingly used to describe the topology and dynamics of complex systems. Here we review the results of the topological analysis of protein structures as molecular networks describing their small-world character,…

生物大分子 · 定量生物学 2007-06-10 Csaba Bode , Istvan A. Kovacs , Mate S. Szalay , Robin Palotai , Tamas Korcsmaros , Peter Csermely

Semiflexible polymers such as filamentous actin play a vital role in the mechanical behavior of cells, yet the basic properties of cross-linked F-actin networks remain poorly understood. To address this issue, we have performed numerical…

软凝聚态物质 · 物理学 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh

Disordered filamentous networks with compliant crosslinks exhibit a low linear elastic shear modulus at small strains, but stiffen dramatically at high strains. Experiments have shown that the elastic modulus can increase by up to three…

We present theoretical and experimental studies of the elastic response of fibrous networks subjected to uniaxial strain. Uniaxial compression or extension is applied to extracellular networks of fibrin and collagen using a shear rheometer…

Biological machines like molecular motors and enzymes operate in dynamic cycles representable as stochastic flows on networks. Current stochastic dynamics describes such flows on fixed networks. Here, we develop a scalable approach to…

统计力学 · 物理学 2026-03-02 Ying-Jen Yang , Ken A. Dill

The training dynamics of linear networks are well studied in two distinct setups: the lazy regime and balanced/active regime, depending on the initialization and width of the network. We provide a surprisingly simple unifying formula for…

机器学习 · 计算机科学 2024-10-31 Zhenfeng Tu , Santiago Aranguri , Arthur Jacot

Reconstituted filamentous actin networks with myosin motor proteins form active gels, in which motor proteins generate forces that drive the network far from equilibrium. This motor activity can also strongly affect the network elasticity;…

软凝聚态物质 · 物理学 2010-09-21 C. P. Broedersz , F. C. MacKintosh

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Responding mechanically to environmental requests, muscles show a surprisingly large variety of functions. The studies of in vivo cycling muscles qualified skeletal muscles into four principal locomotor patterns: motor, brake, strut, and…

生物物理 · 物理学 2009-09-09 Valery B. Kokshenev

We study a non-linear dynamical system on networks inspired by the pitchfork bifurcation normal form. The system has several interesting interpretations: as an interconnection of several pitchfork systems, a gradient dynamical system and…

动力系统 · 数学 2021-08-19 Karel Devriendt , Renaud Lambiotte