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Motor-driven cytoskeletal remodeling in cellular systems can often be accompanied by a diffusive-like effect at local scales, but distinguishing the contributions of the ordering process, such as active contraction of a network, from this…

Intracellular transport of cargoes in the cell is essential for the organization and functioning cells, especially those that are large and elongated. The cytoskeletal networks inside large cells can be highly complex, and this cytoskeletal…

生物物理 · 物理学 2023-08-04 Nimisha Krishnan , Niranjan Sarpangala , Maria Gamez , Ajay Gopinathan , Jennifer L Ross

We study the diffusion of a tracer particle driven out-of-equilibrium by an external force and traveling in a dense environment of arbitrary density. The system evolves on a discrete lattice and its stochastic dynamics is described by a…

Transport of dense core vesicles (DCVs) in neurons is crucial for distributing molecules like neuropeptides and growth factors. We studied the experimental trajectories of dynein-driven directed movement of DCVs in the ALA neuron C. elegans…

亚细胞过程 · 定量生物学 2025-03-04 Anna Gavrilova , Nickolay Korabel , Victoria J. Allan , Sergei Fedotov

We study in detail a one-dimensional lattice model of a continuum, conserved field (mass) that is transferred deterministically between neighbouring random sites. The model falls in a wider class of lattice models capturing the joint effect…

统计力学 · 物理学 2023-11-01 Stefano Lepri , Paolo Politi , Arkady Pikovsky

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

统计力学 · 物理学 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

Diffusion can be conceptualized, at microscopic scales, as the random hopping of particles between neighboring lattice sites. In the case of diffusion in inhomogeneous media, distinct spatial domains in the system may yield distinct…

生物物理 · 物理学 2017-10-02 Yiwei Li , Osman Kahraman , Christoph A. Haselwandter

Fundamental understanding of the effect of microscopic parameters on the dynamics of probe particles in different complex environments has wide implications. Examples include diffusion of proteins in the biological hydrogels, porous media,…

软凝聚态物质 · 物理学 2019-09-11 Praveen Kumar , Ligesh Theeyancheri , Subhasish Chaki , Rajarshi Chakrabarti

Nucleation is a key step in the synthesis of new material from solution. Well-established lattice-gas models can be used to gain insight into the basic physics of nucleation pathways involving a single nucleus type. In many situations a…

统计力学 · 物理学 2023-01-04 Dipanjan Mandal , David Quigley

We study dynamics emergent from a two-dimensional reaction--diffusion process modelled via a finite lattice dynamical system, as well as an analogous PDE system, involving spatially nonlocal interactions. These models govern the evolution…

组织与器官 · 定量生物学 2018-11-14 Andrew L. Krause , Dmitry Beliaev , Robert A. Van Gorder , Sarah L. Waters

We develop and analyze a lattice difference equation (LDE) framework to model the spatial dynamics of invasion in populations. This framework extends beyond classical integro-difference and reaction-diffusion models by incorporating spatial…

动力系统 · 数学 2025-08-13 Eddy Kwessi

In many biological systems, motile agents exhibit random motion with short-term directional persistence, together with crowding effects arising from spatial exclusion. We formulate and study a class of lattice-based models for multiple…

生物物理 · 物理学 2019-11-06 Stephen Zhang , Aaron Chong , Barry D. Hughes

The study of real-life network modeling has become very popular in recent years. An attractive model is the scale-free percolation model on the lattice $\mathbb{Z}^d$, $d\ge1$, because it fulfills several stylized facts observed in large…

概率论 · 数学 2016-09-29 Philippe Deprez , Mario V. Wüthrich

Monte Carlo (MC) simulations of transport in random porous networks indicate that for high variances of the log-normal permeability distribution, the transport of a passive tracer is non-Fickian. Here we model this non-Fickian dispersion in…

计算物理 · 物理学 2018-08-01 Amir H. Delgoshaie , Patrick Jenny , Hamdi A. Tchelepi

We present the results of a numerical investigation of charged-particle transport across a synthesized magnetic configuration composed of a constant homogeneous background field and a multiscale perturbation component simulating an effect…

统计力学 · 物理学 2007-05-23 Francesco Chiaravalloti , Alexander V. Milovanov , Gaetano Zimbardo

Diffusiophoresis, a ubiquitous phenomenon that induces particle transport whenever solute concentration gradients are present, was recently observed in the context of microsystems and shown to strongly impact colloidal transport (patterning…

We study the implications of coupling Langmuir kinetics (LK) process with the dynamics of an extending lattice. The model that we consider couples dynamically extending exclusion process (DEEP) with the process of random attachment and…

软凝聚态物质 · 物理学 2012-12-03 Sudipto Muhuri

We study the dynamics of micron-sized particles on a layer of motile cells. This cell carpet acts as an active bath that propels passive tracer particles via direct mechanical contact. The resulting nonequilibrium transport shows a…

软凝聚态物质 · 物理学 2024-02-27 Robert Großmann , Lara S. Bort , Ted Moldenhawer , Setareh Sharifi Panah , Ralf Metzler , Carsten Beta

Aggregation and fragmentation of single molecules in the cell environment lead to a spectrum of diffusivities and to statistical laws of movement very different from typical Brownian motion. Current models of intracellular transport do not…

统计力学 · 物理学 2020-07-08 M. Hidalgo-Soria , E. Barkai

We study the adsorption and desorption kinetics of interacting particles moving on a one-dimensional lattice. Confinement is introduced by limiting the number of particles on a lattice site. Adsorption and desorption are found to proceed at…

统计力学 · 物理学 2014-12-16 T. Becker , K. Nelissen , B. Cleuren , B. Partoens , C. Van den Broeck