定量方法
A model is presented relating the evolution of genomic GC content over time to AT$\rightarrow$GC and GC$\rightarrow$AT mutation rates. By employing It\^o calculus it is shown that if mutation rates in asexually reproducing organisms are…
Double-strand DNA breaks (DSBs) are a form of DNA damage that can cause abnormal chromosomal rearrangements. Recent technologies based on high-throughput experiments have obvious high costs and technical challenges.Therefore, we design a…
Environmental temperature (ET) often changes the nutrient intake/output for layers. Changing feed formulations based on ET may need to be utilized to obtain optimum performance, shell quality and bone status. This study was conducted to…
Background and Objective: Several studies confirm that the age of hens has a tremendous impact on external and internal egg quality characteristics. Egg production could be at serious risk if egg quality characteristics and age of hens are…
Background and Objective: In the current study, we sought to determine the value of a meta-analysis to improve decision-making processes related to nutrition in the poultry industry. To this end, nine commercial size experiments were…
Advances in satellite imaging and GPS tracking devices have given rise to a new era of remote sensing and geospatial analysis. In environmental science and conservation ecology, biotelemetric data is often high-dimensional, spatially and/or…
In this article, we review existing probabilistic models for modeling abundance of fixed-length strings (k-mers) in DNA sequencing data. These models capture dependence of the abundance on various phenomena, such as the size and repeat…
Background: Kinematics is studied by practitioners and researchers in different fields of practice. It is therefore critically important to adhere to a taxonomy that explicitly describes positions and movements. However, current…
Application of independent component analysis (ICA) as an unmixing and image clustering technique for high spatial resolution Raman maps is reported. A hyperspectral map of a fixed human cell was collected by a Raman micro spectrometer in a…
Medication adherence is a well-known problem for pharmaceutical treatment of chronic diseases. Understanding how nonadherence affects treatment efficacy is made difficult by the ethics of clinical trials that force patients to skip doses of…
Medication adherence is a major problem for patients with chronic diseases that require long term pharmacotherapy. Many unanswered questions surround adherence, including how adherence rates translate into treatment efficacy and how missed…
High throughput experimental systems play an important role in bioprocess development, as they provide an efficient way of analysing different experimental conditions and perform strain discrimination in previous phases to the industrial…
In this article we are describing a new algorithm for detecting and validating partial horizontal gene transfers (HGT). The presented algorithm is based on a sliding window procedure which analyzes fragments of the given multiple sequence…
The use of mathematical models to make predictions about tumor growth and response to treatment has become increasingly more prevalent in the clinical setting. The level of complexity within these models ranges broadly, and the calibration…
Explainable Artificial Intelligence (XAI) has been identified as a viable method for determining the importance of features when making predictions using Machine Learning (ML) models. In this study, we created models that take an…
Synergy theories for multi-component agent mixtures use 1-agent dose-effect relations, assumed known from analyzing previous 1-agent experiments, to calculate baseline Neither-Synergy-Nor-Antagonism mixture dose-effect relations. The most…
The fetal electrocardiogram (fECG) was first recorded from the maternal abdominal surface in the early 1900s. During the past fifty years, the most advanced electronics technologies and signal processing algorithms have been used to convert…
Several neurodegenerative diseases involve the accumulation of cellular DNA damage. Comet assays are a popular way of estimating the extent of DNA damage. Current literature on the use of deep learning to quantify DNA damage presents an…
Cardiac auscultation is one of the most cost-effective techniques used to detect and identify many heart conditions. Computer-assisted decision systems based on auscultation can support physicians in their decisions. Unfortunately, the…
Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardless of the employed fatality measure, the infected population…