神经元与认知
Invasive brain-computer interface (BCI) technology has demonstrated the possibility of restoring brain-controlled walking in paraplegic spinal cord injury patients. However, current implementations of BCI-controlled walking still have…
Animals must constantly make decisions on the move, such as when choosing among multiple options, or "targets", in space. Recent evidence suggests that this results from a recursive feedback between the (vectorial) neural representation of…
Human brain development is a complex and dynamic process that begins during the first weeks of pregnancy and lasts until early adulthood. This chapter focuses on the developmental window from prenatal period to infancy, probably the most…
Premature birth and various pre- and peri-natal stresses can lead to a variety of brain lesions and have clearly been identified as major risk factors for neurodevelopmental disorders, with variable but multiple consequences that can…
Within-frequency coupling (WFC) and cross-frequency coupling (CFC) in brain networks reflect neural synchronization within the same frequency band and cross-band oscillatory interactions, respectively. Their synergy provides a comprehensive…
In the human brain, white matter development is a complex and long-lasting process involving intermingling micro-and macrostructural mechanisms, such as fiber growth, pruning and myelination. Did you know that all these neurodevelopmental…
A single neuron receives an extensive array of synaptic inputs through its dendrites, raising the fundamental question of how these inputs undergo integration and summation, culminating in the initiation of spikes in the soma. Experimental…
Functional theories of consciousness, based on emergence of conscious experiences from the execution of a particular function by an insentient brain, face the hard problem of consciousness of explaining why the insentient brain should…
This study investigated visual impairment complaints in a sample of 948 Acquired Brain Injury (ABI) patients using the DiaNAH dataset, emphasizing advanced machine learning techniques for managing missing data. Patients completed a CVS…
Deep neural networks (DNNs) once showed increasing alignment with primate perception and neural responses as they improved on vision benchmarks, raising hopes that advances in AI would yield better models of biological vision. However, we…
We present a computational model of the mechanisms that may determine infants' behavior in the "mobile paradigm". This paradigm has been used in developmental psychology to explore how infants learn the sensory effects of their actions. In…
Background Seizure severity can change from one seizure to the next within individual people with epilepsy. It is unclear if and how seizure severity is modulated over longer timescales. Characterising seizure severity variability over time…
The human brain is a complex dynamical system which displays a wide range of macroscopic and mesoscopic patterns of neural activity, whose mechanistic origin remains poorly understood. Whole-brain modelling allows us to explore candidate…
To the best of our knowledge, all existing methods that can generate synthetic brain magnetic resonance imaging (MRI) scans for a specific individual require detailed structural or volumetric information about the individual's brain.…
Normative models of brain structure estimate the effects of covariates such as age and sex using large samples of healthy controls. These models can then be applied to e.g. smaller clinical cohorts to distinguish disease effects from other…
Decoding behavior, such as movement, from multiscale brain networks remains a central objective in neuroscience. Over the past decades, artificial intelligence and machine learning have played an increasingly significant role in elucidating…
We propose a model of the functional architecture of curvature sensible cells in the visual cortex that associates curvature with scale. The feature space of orientation and position is naturally enhanced via its oriented prolongation,…
Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…
Motor control requires sensory feedback, and the nature of this feedback has implications for the tasks of the central nervous system (CNS): for an approximately linear mechanical system (e.g., a freely standing person, a rider on a…
This paper studies subtypes of restricted, repetitive and stereotypical behaviors (RRBs) in adolescent males with autism spectrum disorder (ASD) from the viewpoint of the dynamics of brain functional connectivities (FCs). Data from the…