生物物理
The growth and scaling of organs is a fundamental aspect of animal development. However, how organs grow to the right size and shape required by physiological demands, remains largely unknown. Here, we provide a framework combining theory…
Natural selection for terrestrial locomotion has yielded unifying patterns in the body shape of legged animals, often manifesting as scaling laws. One such pattern appears in the frontal aspect ratio. Smaller animals like insects typically…
Predicting favorable protein-peptide binding events remains a central challenge in biophysics, with continued uncertainty surrounding how nonlocal effects shape the global energy landscape. Here, we introduce peripheral surface information…
The Physarum network expands or retracts in response to environmental stimuli, demonstrating an intelligent adaptive capability to locate optimal paths for nutrient transport. The underlying physical mechanism governing this intelligence…
Scaffolds have a key role in the clinical success of tissue engineering for the regeneration of damaged tissues. Their bio-performance is often described as the extent to which they can provide an extracellular matrix-like environment for…
We propose a physical framework for ant navigation of chemical trails. For this, we use controlled experiments in which individuals follow narrow pheromone trails, for which ants display oscillatory motion, as previously reported in the…
Species interactions through cross-feeding via leakage and uptake of chemicals are important in microbial communities, and play an essential role in the coexistence of diverse species. Here, we study a simple dynamical model of a microbial…
A packed community of exponentially proliferating microbes will spread in size exponentially. However, due to nutrient depletion, mechanical constraints, or other limitations, exponential proliferation is not indefinite, and the spreading…
We address the problem of how individuals can integrate efficiently their private behavior with information provided by others within a group. To this end, we consider the model of collective search introduced in…
The PI3K/AKT signaling pathway is triggered by recruitment of AKT to cellular membranes. Although AKT is a multidomain serine/threonine kinase composed of an N-terminal pleckstrin homology (PH) domain and a C-terminal kinase domain, how…
Quantum synchronisation has recently been proposed as a mechanism for electronic excitation energy transfer in light-harvesting complexes, yet its robustness in driven-dissipative settings remains under active investigation. Here, we…
The Chesapeake Bay, one of the largest estuaries in the United States, is an ecological system of great complexity and relevance. The food web is composed of thirty-six trophic components, all of which are functionally connected. In this…
We developed methods for protein synthesis and performed two-dimensional electronic spectroscopy (2D-ES) to examine the influence of pigment arrangement on the photoexcitation dynamics of light-harvesting proteins in phycobilisome. We…
Nitinol (NiTi shape-memory alloy) is an interesting candidate in various medical applications like dental, orthopedic, and cardiovascular devices, owing to its unique mechanical behaviors and proper biocompatibility. The aim of this work is…
Turing patterns are a central paradigm for describing spatial patterns in nature. The corresponding theory of reaction-diffusion dynamics combines ideal diffusion with nonlinear reactions, resulting in patterns when species diffuse at…
Cell motility underlies many biological processes, including cancer metastasis, bacterial infection, and evolutionary adaptation. We introduce a non-equilibrium single-cell motility model inspired by the generalized Langevin equation, which…
SAXS studies of four 60 base-pair DNA duplexes with sequences closely related to part of the GAGE6 (G-antigen 6) promoter have been performed to study the role of DNA conformations in solution and their potential relationship to DNA-protein…
Heat generation and temperature reading at the nanoscale have attracted increasing attention due to their direct relevance in thermal therapeutic approaches. Consequently, huge progress has been made toward the design of dual-function…
Polymorphism has been observed in viral capsid assembly, demonstrating the ability of identical protein dimers to adopt multiple geometries under the same solution conditions. A well-studied example is the hepatitis B virus (HBV), which…
This paper presents a numerical study of the dynamics of DNA double helix breakage under the influence of external forces using the Peyrard-Bishop-Dauxois (PBD) model. The PBD model represents DNA as a chain of nonlinearly coupled…