Resolution and enhancement in nanoantenna-based fluorescence microscopy
Abstract
Single gold nanoparticles can act as nanoantennas for enhancing the fluorescence of emitters in their near-fields. Here we present experimental and theoretical studies of scanning antenna-based fluorescence microscopy as a function of the diameter of the gold nanoparticle. We examine the interplay between fluorescence enhancement and spatial resolution and discuss the requirements for deciphering single molecules in a dense sample. Resolutions better than 20 nm and fluorescence enhancement up to 30 times are demonstrated experimentally. By accounting for the tip shaft and the sample interface in finite-difference time-domain calculations, we explain why the measured fluorescence enhancements are higher in the presence of an interface than the values predicted for a homogeneous environment.
Cite
@article{arxiv.0910.5593,
title = {Resolution and enhancement in nanoantenna-based fluorescence microscopy},
author = {Hadi Eghlidi and Kwang Geol Lee and Xue-Wen Chen and Stephan Goetzinger and Vahid Sandoghdar},
journal= {arXiv preprint arXiv:0910.5593},
year = {2015}
}
Comments
10 pages, 3 figures. accepted for publication in Nano Letters