K-space interpretation of image-scanning-microscopy
Optics
2023-04-19 v1 Signal Processing
Applied Physics
Medical Physics
Abstract
In recent years, image-scanning microscopy (ISM, also termed pixel-reassignment microscopy) has emerged as a technique that improves the resolution and signal-to-noise compared to confocal and widefield microscopy by employing a detector array at the image plane of a confocal laser scanning microscope. Here, we present a k-space analysis of coherent ISM, showing that ISM is equivalent to spotlight synthetic-aperture radar (SAR) and analogous to oblique-illumination microscopy. This insight indicates that ISM can be performed with a single detector placed in the k-space of the sample, which we numerically demonstrate.
Cite
@article{arxiv.2301.04353,
title = {K-space interpretation of image-scanning-microscopy},
author = {Tal I. Sommer and Gil Weinberg and Ori Katz},
journal= {arXiv preprint arXiv:2301.04353},
year = {2023}
}