来自蛋白质纳米晶体气溶胶束的飞秒X射线衍射
生物物理
2018-02-20 v3
摘要
我们展示了使用X射线自由电子激光从气溶胶化的单个颗粒病毒晶体获得的近原子分辨率布拉格衍射。气溶胶喷射器的形式几乎与传统液体微射流喷嘴相同，但通过使用氦载气而非液体，X射线散射背景降低了几个数量级。该方法为研究小晶体产生的弱弥散或晶格变换信号提供了一条途径。颗粒的高速度特别适合于即将到来的MHz重复频率X射线自由电子激光。
引用
@article{arxiv.1702.04014,
title = {Femtosecond x-ray diffraction from an aerosolized beam of protein nanocrystals},
author = {Salah Awel and Richard A. Kirian and Max O. Wiedorn and Kenneth R. Beyerlein and Nils Roth and Daniel A. Horke and Dominik Oberthür and Juraj Knoska and Valerio Mariani and Andrew Morgan and Luigi Adriano and Alexandra Tolstikova and P. Lourdu Xavier and Oleksandr Yefanov and Andrew Aquila and Anton Barty and Shatabdi Roy-Chowdhury and Mark S. Hunter and Daniel James and Joseph S. Robinson and Uwe Weierstall and Andrei V. Rode and Saša Bajt and Jochen Küpper and Henry N. Chapman},
journal= {arXiv preprint arXiv:1702.04014},
year = {2018}
}