Base sequence dependent sliding of proteins on DNA
Biomolecules
2011-07-13 v1 Soft Condensed Matter
Biological Physics
Abstract
The possibility that the sliding motion of proteins on DNA is influenced by the base sequence through a base pair reading interaction, is considered. Referring to the case of the T7 RNA-polymerase, we show that the protein should follow a noise-influenced sequence-dependent motion which deviate from the standard random walk usually assumed. The general validity and the implications of the results are discussed.
Keywords
Cite
@article{arxiv.q-bio/0403028,
title = {Base sequence dependent sliding of proteins on DNA},
author = {M. Barbi and C. Place and V. Popkov and M. Salerno},
journal= {arXiv preprint arXiv:q-bio/0403028},
year = {2011}
}
Comments
12 pages, 3 figures