English

A mini-review of the diffusion dynamics of DNA-binding proteins: Experiments and models

Biological Physics 2021-02-24 v1

Abstract

In the course of various biological processes, specific DNA-binding proteins must find a particular target sequence/protein or a damaged site on the DNA efficiently. DNA-binding proteins perform this task based on diffusion. Yet, investigations over recent decades have found that the diffusion dynamics of DNA-binding proteins are generally complicated and, further, protein-specific. In this review, we collect the experimental and theoretical studies that quantify the diffusion dynamics of DNA-binding proteins and review them from the viewpoint of diffusion processes.

Keywords

Cite

@article{arxiv.2011.00219,
  title  = {A mini-review of the diffusion dynamics of DNA-binding proteins: Experiments and models},
  author = {Seongyu Park and O-chul Lee and Xavier Durang and Jae-Hyung Jeon},
  journal= {arXiv preprint arXiv:2011.00219},
  year   = {2021}
}