A continuous model for cell sorting
组织与器官
2007-05-23 v1
摘要
The differential Adhesion Hypothesis (DAH) is a theory of the organization of cells within a tissue. In this study we introduce a stochastic model supporting the DAH, that can be seen as a continuous version of a discrete model of Graner and Glazier. Our approach is based on the mathematical framework of Gibbsian marked point processes. We provide a Markov chain Monte Carlo algorithm that can reproduce classical biological patterns, and we propose an estimation procedure for a parameter that quantifies the strength of adhesion between cells. This procedure is tested through simulations.
引用
@article{arxiv.q-bio/0605035,
title = {A continuous model for cell sorting},
author = {Mathieu Emily and Olivier Francois},
journal= {arXiv preprint arXiv:q-bio/0605035},
year = {2007}
}
备注
21 pages; 6 Figures; 1 Table