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Motor enzymes are remarkable molecular machines that use the energy derived from the hydrolysis of a nucleoside triphosphate to generate mechanical movement, achieved through different steps that constitute their kinetic cycle. These…

Subcellular Processes · Quantitative Biology 2014-09-05 Luca Ciandrini , M. Carmen Romano , A. Parmeggiani

Controllable nonlinear quantum interactions are a much sought after target for modern quantum technologies. They are typically difficult and costly to engineer for bespoke purposes. However controllable nonlinearities may have always been…

Quantum Physics · Physics 2025-11-25 Luca Ornigotti , Darren W. Moore , Radim Filip

The assumption of linear response of protein molecules to thermal noise or structural perturbations, such as ligand binding or detachment, is broadly used in the studies of protein dynamics. Conformational motions in proteins are…

Biomolecules · Quantitative Biology 2010-06-21 Yuichi Togashi , Toshio Yanagida , Alexander S. Mikhailov

The thermal activation process by which a system passes from one local energy minimum to another is a recurring motif in physics, chemistry, and biology. For instance, biopolymer chains are typically modeled in terms of energy landscapes,…

Statistical Mechanics · Physics 2024-10-01 Sudeep Adhikari , K. S. D. Beach

We study the mechanical and thermodynamic properties of different traffic models for kinesin which are relevant in biological and experimental contexts. We find that motor-motor interactions play a fundamental role by enhancing the…

Statistical Mechanics · Physics 2013-07-18 Natalia Golubeva , Alberto Imparato

Cross phenomena, representing responses of a system to external stimuli, are ubiquitous from quantum to macro scale. The Onsager theorem is often used to describe them, stating that the coefficient matrix of cross phenomena connecting the…

Materials Science · Physics 2023-03-28 Zi-Kui Liu

We propose a simple theoretical model for a molecular chemical engine that catalyzes a chemical reaction and converts the free energy released by the reaction into mechanical work. Binding and unbinding processes of reactant and product…

Statistical Mechanics · Physics 2018-05-22 Kazuo Sasaki

Molecular motors belonging to the kinesin and myosin super family hydrolyze ATP by cycling through a sequence of chemical states. These cytoplasmic motors are dimers made up of two linked identical monomeric globular proteins. Fueled by the…

Biological Physics · Physics 2022-12-28 Ryota Takaki , Mauro L. Mugnai , D. Thirumalai

In many organisms, cell division is driven by the constriction of a cytokinetic ring, which consists of actin filaments and crosslinking proteins. While it has long been believed that the constriction is driven by motor proteins, it has…

Biological Physics · Physics 2023-07-26 Alexander Cumberworth , Pieter Rein ten Wolde

The actomyosin cytoskeleton, a protein assembly comprising actin fibers and the myosin molecular motor, drives various cellular dynamics through contractile force generation at high densities. However, the relationship between the density…

Soft Condensed Matter · Physics 2025-01-07 Tomoka Kashiwabara , Tatsuya Fukuyama , Yusuke T. Maeda

Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is…

Statistical Mechanics · Physics 2009-12-04 Stefan Klumpp , Melanie J. I. Müller , Reinhard Lipowsky

The emergence of a body axis is a fundamental step in the development of multicellular organisms. In simple systems such as $\textit{Hydra}$, growing evidence suggests that mechanical forces generated by collective cellular activity play a…

Soft Condensed Matter · Physics 2026-01-09 Arthur Hernandez , Cuncheng Zhu , Luca Giomi

Friction experiments were conducted on hydrogel thin films sliding against a rigid sphere in a low velocity regime where molecular adsorption at the sliding interface sets the friction force, through a dissipative…

Soft Condensed Matter · Physics 2024-12-10 Lola Ciapa , Yvette Tran , Christian Frétigny , Antoine Chateauminois , Emilie Verneuil

The cytoskeleton is an active composite of filamentous proteins that dictates diverse mechanical properties and processes in eukaryotic cells by generating forces and autonomously restructuring itself. Enzymatic motors that act on the…

Enzymatic molecules that actively support many cellular processes, including transport, cell division and cell motility, are known as motor proteins or molecular motors. Experimental studies indicate that they interact with each other and…

Biological Physics · Physics 2015-05-20 Daniel Celis-Garza , Hamid Teimouri , Anatoly B. Kolomeisky

Interaction between local magnetization and conduction electrons is responsible for a variety of phenomena in magnetic materials. We have shown that the spin-dependent motive force induced by magnetization dynamics in a conducting…

Mesoscale and Nanoscale Physics · Physics 2022-07-26 I. I. Lyapilin

For one-dimensional many-body systems interacting via the \textit{Coulomb force} and with \textit{arbitrary} external potential energy, we derive (\textit{i}) the \textit{node coalescence condition} for the wave function. This condition…

Materials Science · Physics 2007-05-23 Xiao-Yin Pan , Viraht Sahni

We review the properties of biological motor proteins which move along linear filaments that are polar and periodic. The physics of the operation of such motors can be described by simple stochastic models which are coupled to a chemical…

Biological Physics · Physics 2009-10-31 Frank Julicher

Myosin-V is a motor protein responsible for organelle and vesicle transport in cells. Recent single-molecule experiments have shown that it is an efficient processive motor that walks along actin filaments taking steps of mean size close to…

Statistical Mechanics · Physics 2009-11-07 Anatoly B. Kolomeisky , Michael E. Fisher

This paper deals with the complex problem of how to simulate multiparticle contacts. The collision process is responsible for the transfer and dissipation of energy in granular media. A novel model of the interaction force between particles…

Computational Physics · Physics 2007-05-23 Leszczynski Jacek