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In large asexual populations, multiple beneficial mutations arise in the population, compete, interfere with each other, and accumulate on the same genome, before any of them fix. The resulting dynamics, although studied by many authors, is…

Populations and Evolution · Quantitative Biology 2015-06-11 Daniel S. Fisher

We consider two population models subject to the evolutionary forces of selection and mutation, the Moran model and the $\Lambda$-Wright-Fisher model. In such models the block counting process traces back the number of potential ancestors…

Probability · Mathematics 2023-04-26 Fernando Cordero , Martin Möhle

Consider a two-type Moran population of size $N$ with selection and mutation, where the selective advantage of the fit individuals is amplified at extreme environmental conditions. Assume selection and mutation are weak with respect to $N$,…

Probability · Mathematics 2023-04-26 Fernando Cordero , Grégoire Véchambre

We introduce and analyse an individual-based evolutionary model, in which a population of genetically diverse organisms compete with each other for limited resources. Through theoretical analysis and stochastic simulations, we show that the…

Populations and Evolution · Quantitative Biology 2012-11-02 Tim Rogers , Alan J. McKane , Axel G. Rossberg

For a population with any given number of types, we construct a new multivariate Moran process with frequency-dependent selection and establish, analytically, a correspondence to equilibrium Lotka-Volterra phenomenology. This…

Populations and Evolution · Quantitative Biology 2015-05-30 Andrew E. Noble , Alan Hastings , William F. Fagan

This article deals with the emergence of a specific mating preference pattern called homogamy in a population. Individuals are characterized by their genotype at two haploid loci, and the population dynamics is modelled by a non-linear…

Probability · Mathematics 2019-09-25 Coron Camille , Costa Manon , Laroche Fabien , Leman Hélène , Smadi Charline

Community assembly is studied using individual-based multispecies models. The models have stochastic population dynamics with mutation, migration, and extinction of species. Mutants appear as a result of mutation of the resident species,…

Populations and Evolution · Quantitative Biology 2010-05-18 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

Probability · Mathematics 2022-04-27 Nam H Nguyen , Marek Kimmel

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

Tumors initiate when a population of proliferating cells accumulates a certain number and type of genetic and/or epigenetic alterations. The population dynamics of such sequential acquisition of (epi)genetic alterations has been the topic…

Populations and Evolution · Quantitative Biology 2015-04-09 Peter Ashcroft , Franziska Michor , Tobias Galla

In species reproducing both sexually and asexually clones are often more common in recently established populations. Earlier studies have suggested that this pattern arises from natural selection favouring asexual recruitment in young…

Populations and Evolution · Quantitative Biology 2017-12-06 M. Rafajlovic , D. Kleinhans , C. Gulliksson , J. Fries , D. Johansson , A. Ardehed , L. Sundqvist , R. T. Pereyra , B. Mehlig , P. R. Jonsson , K. Johannesson

We study two models of population with migration. We assume that we are given infinitely many islands with the same number r of resources, each individual consuming one unit of resources. On an island lives an individual whose genealogy is…

Probability · Mathematics 2012-06-27 Raoul Normand

The Moran process is a foundational model of genetic drift and mutation in finite populations. In its standard two-allele form with population size $n$, allele counts, and hence allele frequencies, change through stochastic replacement and…

Populations and Evolution · Quantitative Biology 2026-01-16 Dan Braha , Marcus A. M. de Aguiar

We consider the mutation--selection differential equation with pairwise interaction (or, equivalently, the diploid mutation--selection equation) and establish the corresponding ancestral process, which is a random tree and a variant of the…

Probability · Mathematics 2023-04-26 Ellen Baake , Fernando Cordero , Sebastian Hummel

We consider a model of a population of fixed size $N$ undergoing selection. Each individual acquires beneficial mutations at rate $\mu_N$, and each beneficial mutation increases the individual's fitness by $s_N$. Each individual dies at…

Probability · Mathematics 2015-07-03 Jason Schweinsberg

The concept of fitness is central to evolution, but it quantifies only the expected number of offspring an individual will produce. The actual number of offspring is also subject to noise, arising from environmental or demographic…

Populations and Evolution · Quantitative Biology 2022-09-07 Guocheng Wang , Qi Su , Long Wang , Joshua B. Plotkin

Comprehensive models of stochastic, clonally reproducing populations are defined in terms of general branching processes, allowing birth during maternal life, as for higher organisms, or by splitting, as in cell division. The populations…

Populations and Evolution · Quantitative Biology 2014-10-14 Kais Hamza , Peter Jagers , Fima C. Klebaner

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

Biological Physics · Physics 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan

We introduce a stochastic model of a population with overlapping generations and arbitrary levels of self-fertilization versus outcrossing. We study how the global graph of reproductive relationships, or population pedigree, influences the…

Populations and Evolution · Quantitative Biology 2025-05-20 Maximillian Newman , John Wakeley , Wai-Tong Louis Fan

To our knowledge, the populations are generally assumed to be homogeneous in the traditional approach to evolutionary game dynamics. Here, we focus on the inhomogeneous populations. A simple model which can describe the inhomogeneity of the…

Physics and Society · Physics 2007-05-23 Xiaojie Chen , Feng Fu , Long Wang , Tianguang Chu
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