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Many important questions in infectious disease epidemiology involve the effects of covariates (e.g., age or vaccination status) on infectiousness and susceptibility, which can be measured in studies of transmission in households or other…

Applications · Statistics 2025-06-27 Yushuf Sharker , Zaynab Diallo , Wasiur R. KhudaBukhsh , Eben Kenah

The appearance of the coronavirus (COVID-19) in late 2019 has dominated the news in the last few months as it developed into a pandemic. In many mathematics and physics classrooms, instructors are using the time series of the number of…

Physics Education · Physics 2020-07-24 Paulo H. Acioli

We present a study of the worldwide spread of a pandemic influenza and its possible containment at a global level taking into account all available information on air travel. We studied a metapopulation stochastic epidemic model on a global…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alain-Jacques Valleron , Alessandro Vespignani

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

Physics and Society · Physics 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta

Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic…

Populations and Evolution · Quantitative Biology 2011-11-22 Trevor Bedford , Andrew Rambaut , Mercedes Pascual

We study two simple mathematical models of the epidemic. At first, we study the repetitive infection spreading in a simplified SIRS model including the effect of the decay of the acquired immune. The model is an intermediate model of the…

Populations and Evolution · Quantitative Biology 2024-03-13 Hidetsugu Sakaguchi , Keito Yamasaki

A novel point process model continuous in space-time is proposed for quantifying the transmission dynamics of the two most common meningococcal antigenic sequence types observed in Germany 2002-2008. Modelling is based on the conditional…

Methodology · Statistics 2015-08-25 Sebastian Meyer , Johannes Elias , Michael Höhle

High order structures (cavities and cliques) of the gene network of influenza A virus reveal tight associations among viruses during evolution and are key signals that indicate viral cross-species infection and cause pandemics. As…

Genomics · Quantitative Biology 2022-11-08 Junjie Li , Jietong Zhao , Yanqing Su , Jiahao Shen , Yaohua Liu , Xinyue Fan , Zheng Kou

We investigate the effects of cooperativity between contagion processes that spread and persist in a host population. We propose and analyze a dynamical model in which individuals that are affected by one transmissible agent $A$ exhibit a…

Physics and Society · Physics 2017-11-22 Li Chen , Fakhteh Ghanbarnejad , Dirk Brockmann

A key problem in modelling the evolution dynamics of infectious diseases is the mathematical representation of the mechanism of transmission of the contagion. Models with a finite number of subpopulations can be described via systems of…

Optimization and Control · Mathematics 2017-03-09 Sebastian Anita , Vincenzo Capasso

In this paper, we carry out a computational study using the spectral decomposition of the fluctuations of a two-pathogen epidemic model around its deterministic attractor, i.e., steady state or limit cycle, to examine the role of partial…

Populations and Evolution · Quantitative Biology 2017-11-01 Yury E. García , Marcos A. Capistrán

The SIR model with spatially inhomogeneous infection rate is studied with numerical simulations in one, two, and three dimensions, considering the case that the infection spreads inhomogeneously in densely populated regions or hot spots. We…

Medical Physics · Physics 2020-12-25 Hidetsugu Sakaguchi , Yuta Nakao

We study the spread of multi-competitive viruses over a (possibly) time-varying network of individuals accounting for the presence of shared infrastructure networks that further enables transmission of the virus. We establish a sufficient…

Systems and Control · Electrical Eng. & Systems 2023-03-17 Sebin Gracy , Yuan Wang , Philip E. Pare , Cesar A Uribe

We introduce a kinetic model that couples the movement of a population of individuals with the dynamics of a pathogen in the same population. We consider that transmission occurs when a susceptible and an infectious individual are…

Analysis of PDEs · Mathematics 2026-01-30 Carolina Strecht-Fernandes , Fabio A. C. C. Chalub

An individual-based model of the infectious disease spread among the urban population is considered. A system of stochastic equations, which describes changes in quantities of four population groups, susceptible, exposed, infected…

Populations and Evolution · Quantitative Biology 2011-11-11 Vasiliy Leonenko

A model for 1D traffic flow is developed, which is discrete in space and time. Like the cellular automaton model by Nagel and Schreckenberg [J. Phys. I France 2, 2221 (1992)], it is simple, fast, and can describe stop-and-go traffic. Due to…

Statistical Mechanics · Physics 2009-10-31 Dirk Helbing , Michael Schreckenberg

The critical properties of a cellular automaton model describing the spreading of infection of the Herpes Simplex Virus in corneal tissue are investigated through the dynamic Monte Carlo method. The model takes into account different cell…

Biological Physics · Physics 2007-05-23 Claudia Pio Ferreira , Jose Fernando Fontanari , Rita M. Zorzenon dos Santos

The spreading of epidemics is very much determined by the structure of the contact network, which may be impacted by the mobility dynamics of the individuals themselves. In confined scenarios where a small, closed population spends most of…

Physics and Society · Physics 2018-05-09 Clara Granell , Peter J. Mucha

We study a cellular automaton model, which allows diffusion of energy (or equivalently any other physical quantities such as mass of a particular compound) at every lattice site after each timestep. Unit amount of energy is randomly added…

Condensed Matter · Physics 2009-10-22 T. C. Chan , H. F. Chau , K. S. Cheng

Among various possible causes of autoimmune disease, an important role is played by infections that can result in a breakdown of immune tolerance, primarily through the mechanism of "molecular mimicry". In this paper we propose and analyse…

Tissues and Organs · Quantitative Biology 2018-05-21 F. Fatehi , S. N. Kyrychko , A. Ross , Y. N. Kyrychko , K. B. Blyuss