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Although there are theoretical studies on the thermodynamics of ion channels, an investigation involving the thermodynamics of coupled channels has not been proposed. To overcome this issue, we developed calculations to present a…

Biological Physics · Physics 2022-08-29 D. O. C. Santos , M. A. S. Trindade , A. J. da Silva

Ion channels are membrane proteins responsible for an enormous range of biological functions. Ion selectivity and permeation are based on simple laws of physics and chemistry. Ion channels are therefore ideal candidates for physical…

Biological Physics · Physics 2012-06-14 Janhavi Giri

Understanding ion-transport under molecular confinement is essential for developing next-generation energy technologies, where ionic motion often occurs within nanoscale or angstrom-scale channels. In this study, we use the model system of…

The goal of this paper is two-fold. First, to establish a tractable model for the underwater acoustic channel useful for network optimization in terms of convexity. Second, to propose a network coding based lower bound for transmission…

Information Theory · Computer Science 2008-09-02 Daniel E. Lucani , Muriel Médard , Milica Stojanovic

We consider a class of systems where, due to the large mismatch of dielectric constants, the Coulomb interaction is approximately one-dimensional. Examples include ion channels in lipid membranes and water filled nanopores in silicon or…

Statistical Mechanics · Physics 2015-06-25 A. Kamenev , J. Zhang , A. I. Larkin , B. I. Shklovskii

Selectivity filter is a gate in ion channels which are responsible for the selection and fast conduction of particular ions across the membrane (with high throughput rates of $10^8$ ions/sec and a high 1:$10^4$ discrimination rate between…

Biological Physics · Physics 2018-09-24 Amir Jalalinejad , Hassan Bassereh , Vahid Salari , Tapio Ala-Nissila , Achille Giacometti

A quantized physical framework, called the five-anchor model, is developed for a general understanding of the working mechanism of ion channels. According to the hypotheses of this model, the following two basic physical principles are…

Neurons and Cognition · Quantitative Biology 2018-08-07 Hao Wang , Jiahui Wang , Xin Yuan Thow , Chengkuo Lee

Stochastic thermodynamics has largely succeeded in characterizing both equilibrium and far-from-equilibrium phenomena. Yet many opportunities remain for application to mesoscopic complex systems -- especially biological ones -- whose…

Statistical Mechanics · Physics 2022-11-08 Mikhael T. Semaan , James P. Crutchfield

In order to characterize the channel capacity of a wavelength channel in a wavelength-division multiplexed (WDM) system, statistical models are needed for the transmitted signals on the other wavelengths. For example, one could assume that…

Information Theory · Computer Science 2024-01-25 Erik Agrell , Magnus Karlsson

Cells are known to utilize biochemical noise to probabilistically switch between distinct gene expression states. We demonstrate that such noise-driven switching is dominated by tails of probability distributions and is therefore…

Molecular Networks · Quantitative Biology 2009-11-13 Pankaj Mehta , Ranjan Mukhopadhyay , Ned S. Wingreen

The flow of ions through permeable channels causes voltage drop in physiological nanodomains such as synapses, dendrites and dendritic spines, and other protrusions. How the voltage changes around channels in these nanodomains has remained…

Soft Condensed Matter · Physics 2025-01-10 Frédéric Paquin-Lefebvre , David Holcman

Presence of multiple antennas on both sides of a communication channel promises significant improvements in system throughput and power efficiency. In effect, a new class of large multiple-input multiple-output (MIMO) communication systems…

Information Theory · Computer Science 2014-01-28 Maksym A. Girnyk , Mikko Vehkaperä , Lars K. Rasmussen

The canalizing properties of biological functions have been mainly studied in the context of Boolean modelling of gene regulatory networks. An important mathematical consequence of canalization is a low average sensitivity, which ensures in…

Combinatorics · Mathematics 2023-07-04 Élisabeth Remy , Paul Ruet

During the last decade, it has been well understood that communication over multiple antennas can increase linearly the multiplexing capacity gain and provide large spectral efficiency improvements. However, the majority of studies in this…

Information Theory · Computer Science 2011-05-31 Symeon Chatzinotas , Bjorn Ottersten

This paper studies on-chip communication with non-ideal heat sinks. A channel model is proposed where the variance of the additive noise depends on the weighted sum of the past channel input powers. It is shown that, depending on the…

Information Theory · Computer Science 2016-11-15 Tobias Koch , Amos Lapidoth , Paul P. Sotiriadis

We study the capacity of discrete memoryless many-to-one interference channels, i.e., K user interference channels where only one receiver faces interference. For a class of many-to-one interference channels, we identify a noisy…

Information Theory · Computer Science 2009-12-17 Viveck R. Cadambe , Syed A. Jafar

An unresolved challenge facing electronics at a few-nm scale is that resistive channels start leaking due to quantum tunneling. This affects the performance of nanoscale transistors, with single-molecule devices displaying particularly low…

Polymer materials with low water uptake exhibit a highly heterogeneous interior, characterized by water clusters in the form of nanodroplets and nanochannels. Here, based on our recent insights from computer simulations, we argue that water…

Soft Condensed Matter · Physics 2022-06-16 Matej Kanduč , Rafael Roa , Won Kyu Kim , Joachim Dzubiella

We propose a new channel model for channels with synchronization errors. Using this model, we give simple, non-trivial and, in some cases, tight lower bounds on the capacity for certain synchronization error channels.

Information Theory · Computer Science 2011-06-02 Aravind R. Iyengar , Paul H. Siegel , Jack K. Wolf

Cold ions in anisotropic harmonic potentials can form ion chains of various sizes. Here, the density of ions is not uniform, thus the eigenmodes are not phononic-like waves. We study chains of N>>1 ions and evaluate analytically the long…

Statistical Mechanics · Physics 2009-11-10 Giovanna Morigi , Shmuel Fishman