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Neurodevelopmental disorders such as Fragile X Syndrome (FXS) and Autism Spectrum Disorder (ASD) are characterized by disrupted cortical oscillatory activity, particularly in the alpha and gamma frequency bands. These abnormalities are…

Neurons and Cognition · Quantitative Biology 2025-11-14 Zag ElSayed , Grace Westerkamp , Jack Yanchen Liu , Ernest Pedapati

Generation of mechanical oscillation is ubiquitous to wide variety of intracellular processes. We show that catchbonding behaviour of motor proteins provides a generic mechanism of generating spontaneous oscillations in motor-cytoskeletal…

Subcellular Processes · Quantitative Biology 2021-11-11 Sougata Guha , MIthun K. Mitra , Ignacio Pagonabarraga , Sudipto Muhuri

Cells generally convert nutrient resources to useful products via energy transduction. Accordingly, the thermodynamic efficiency of this conversion process is one of the most essential characteristics of living organisms. However, although…

Biological Physics · Physics 2016-05-04 Yusuke Himeoka , Kunihiko Kaneko

Living materials adapt their shape to signals from the environment, yet the impact of shape changes on signal processing and associated feedback dynamics remain unclear. We find that droplets with signal-responsive interfacial tensions…

Soft Condensed Matter · Physics 2026-01-27 Tim Dullweber , Roman Belousov , Camilla Autorino , Nicoletta Petridou , Anna Erzberger

Coordinated responses to environmental stimuli are critical for multicellular organisms. To overcome the obstacles of cell-to-cell heterogeneity and noisy signaling dynamics within individual cells, cells must effectively exchange…

Biological Physics · Physics 2022-10-12 Guanyu Li , Ryan LeFebre , Alia Starman , Patrick Chappell , Andrew Mugler , Bo Sun

Oscillators have two main limitations: their synchronization properties are limited (i.e they have a finite synchronization region) and they have no memory of past interactions (i.e. they return to their intrinsic frequency whenever the…

Dynamical Systems · Mathematics 2021-08-18 Ludovic Righetti , Jonas Buchli , Auke J. Ijspeert

Neural oscillations can enhance feature recognition, modulate interactions between neurons, and improve learning and memory. Simulational studies have shown that coherent oscillations give rise to windows in time during which information…

Neurons and Cognition · Quantitative Biology 2014-10-07 Andrew T. Sornborger , Louis Tao

The complex dynamics of intracellular calcium regulates cellular responses to information encoded in extracellular signals. Here, we study the encoding of these external signals in the context of the Li-Rinzel model. We show that by control…

Cell Behavior · Quantitative Biology 2008-06-17 Maurizio De Pitta , Vladislav Volman , Herbert Levine , Giovanni Pioggia , Danilo De Rossi , Eshel Ben-Jacob

We aim to understand the formation of abnormal waves of activity from myocardial regions with diminished cell-to-cell coupling. In route to this goal, we studied the behavior of a heterogeneous myocyte network in which a sharp coupling…

Tissues and Organs · Quantitative Biology 2009-11-13 V. N. Biktashev , A. Arutunyan , N. A. Sarvazyan

In many cases, the computation of a neural system can be reduced to a receptive field, or a set of linear filters, and a thresholding function, or gain curve, which determines the firing probability; this is known as a linear/nonlinear…

Neurons and Cognition · Quantitative Biology 2014-11-12 Sungho Hong , Brian N. Lundstrom , Adrienne Fairhall

We study the impact of noise on a neural population rate model of up and down states. Up and down states are typically observed in neuronal networks as a slow oscillation, where the population switches between high and low firing rates…

Neurons and Cognition · Quantitative Biology 2015-04-24 Zachary McCleney , Zachary P. Kilpatrick

Co-evolutionary adaptive mechanisms are not only ubiquitous in nature, but also beneficial for the functioning of a variety of systems. We here consider an adaptive network of oscillators with a stochastic, fitness-based, rule of…

Physics and Society · Physics 2016-06-08 Young-Ho Eom , Stefano Boccaletti , Guido Caldarelli

Time-dependent numerical studies of line-driven winds using the Sobolev approximation have a history spanning over three decades. In many of these studies, the wind solutions display notorious oscillations. Two clues suggest the…

Astrophysics of Galaxies · Physics 2025-04-23 Joshua Key , Daniel Proga , Randall Dannen , Sterling Vivier , Timothy Waters

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

Biological Physics · Physics 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto

Current scientific consensus holds that sound is transmitted, solely mechanically, from the tympanum to the cochlea via ossicles. But this theory does not explain the hearing extreme quality regarding high frequencies in mammals. So, we…

We hypothesized that rhythmic motor acts entrain neural oscillations in speech production brain regions. We tested this hypothesis in an experiment where a subject produced consonant-vowel (CV) syllables in a rhythmic fashion, while we…

Neurons and Cognition · Quantitative Biology 2016-06-09 Joaquin Rapela

According to the acoustic fluidization hypothesis, elastic waves at a characteristic frequency form inside seismic faults even in the absence of an external perturbation. These waves are able to generate a normal stress which contrasts the…

Statistical Mechanics · Physics 2018-02-14 F. Giacco , L. de Arcangelis , M. Pica Ciamarra , E. Lippiello

Oscillatory activities are widely observed in specific frequency bands of recorded field potentials in different brain regions, and play critical roles in processing neural information. Understanding the structure of these oscillatory…

Neurons and Cognition · Quantitative Biology 2015-07-23 Pengsheng Zheng

The learning and recognition of object features from unregulated input has been a longstanding challenge for artificial intelligence systems. Brains are adept at learning stable representations given small samples of noisy observations;…

Neurons and Cognition · Quantitative Biology 2024-09-30 Roy Moyal , Kyrus R. Mama , Matthew Einhorn , Ayon Borthakur , Thomas A. Cleland

Macroscopic properties and shapes of biological tissues depend on the remodelling of cell-cell junctions at the microscopic scale. We propose a theoretical framework that couples a vertex model of solid confluent tissues with the dynamics…

Soft Condensed Matter · Physics 2020-12-02 Clement Zankoc , Matej Krajnc