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The immune system is a highly parallel and distributed intelligent system which has learning, memory, and associative capabilities. Artificial Immune System is an evolutionary paradigm inspired by the biological aspects of the immune system…

Cryptography and Security · Computer Science 2011-02-22 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

Network intrusion detection is the problem of detecting unauthorised use of, or access to, computer systems over a network. Two broad approaches exist to tackle this problem: anomaly detection and misuse detection. An anomaly detection…

Neural and Evolutionary Computing · Computer Science 2012-08-03 Simon T. Powers , Jun He

Artificial immune systems, more specifically the negative selection algorithm, have previously been applied to intrusion detection. The aim of this research is to develop an intrusion detection system based on a novel concept in immunology,…

Artificial Intelligence · Computer Science 2016-11-17 Julie Greensmith , Jamie Twycross , Uwe Aickelin

Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in…

Computational Engineering, Finance, and Science · Computer Science 2013-07-09 Grazziela P. Figueredo , Peer-Olaf Siebers , Uwe Aickelin , Stephanie Foan

Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity. This paper reviews the biological principles and properties of innate immunity…

Artificial Intelligence · Computer Science 2010-07-05 Jamie Twycross , Uwe Aickelin

Understanding and modelling the complexity of the immune system is a challenge that is shared by the ImmunoComplexiT$^1$ thematic network from the RNSC. The immune system is a complex biological, adaptive, highly diversified, self-organized…

Quantitative Methods · Quantitative Biology 2020-08-27 Véronique Thomas-Vaslin

For over a century, immunology has masterfully discovered and dissected the components of our immune system, yet its collective behavior remains fundamentally unpredictable. In this perspective, we argue that building on the learnings of…

Artificial immune systems primarily mimic the adaptive nature of biological immune functions. Their ability to adapt to varying pathogens makes such systems a suitable choice for various robotic applications. Generally, AIS-based robotic…

Robotics · Computer Science 2012-02-21 Ali Raza , Benito R. Fernandez

Dendritic cells are the crime scene investigators of the human immune system. Their function is to correlate potentially anomalous invading entities with observed damage to the body. The detection of such invaders by dendritic cells results…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin

Anomaly detection is a well-established field in machine learning, identifying observations that deviate from typical patterns. The principles of anomaly detection could enhance our understanding of how biological systems recognize and…

Populations and Evolution · Quantitative Biology 2025-10-30 Steven A. Frank

Natural Immune system plays a vital role in the survival of the all living being. It provides a mechanism to defend itself from external predates making it consistent systems, capable of adapting itself for survival incase of changes. The…

Artificial Intelligence · Computer Science 2011-03-11 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

Dendritic cells are antigen presenting cells that provide a vital link between the innate and adaptive immune system, providing the initial detection of pathogenic invaders. Research into this family of cells has revealed that they perform…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin , Gianni Tedesco

The major function of this model is to access the UCI Wisconsin Breast Can- cer data-set[1] and classify the data items into two categories, which are normal and anomalous. This kind of classifi cation can be referred as anomaly detection,…

Artificial Intelligence · Computer Science 2010-07-05 Feng Gu , Uwe Aickelin , Julie Greensmith

The adaptive immune system provides a diverse set of molecules that can mount specific responses against a multitude of pathogens. Memory is a key feature of adaptive immunity, which allows organisms to respond more readily upon…

Populations and Evolution · Quantitative Biology 2021-04-14 Oskar H Schnaack , Armita Nourmohammad

Dendritic Cells (DCs) are innate immune system cells which have the power to activate or suppress the immune system. The behaviour of human of human DCs is abstracted to form an algorithm suitable for anomaly detection. We test this…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin

The immune system recognizes a myriad of invading pathogens and their toxic products. It does so with a finite repertoire of antibodies and T cell receptors. We here describe theories that quantify the immune system dynamics. We describe…

Populations and Evolution · Quantitative Biology 2010-10-05 Michael W. Deem , Pooya Hejazi

Artificial immune system can be used to generate schedules in changing environments and it has been proven to be more robust than schedules developed using a genetic algorithm. Good schedules can be produced especially when the number of…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Edmund Burke , Aniza Din

There is no agreed definition of intelligence, so it is problematic to simply ask whether brains, swarms, computers, or other systems are intelligent or not. To compare the potential intelligence exhibited by different cognitive systems, I…

Artificial Intelligence · Computer Science 2021-08-12 Carlos Gershenson

Modeling the immune system so that its essential functionalities stand out without the need for every molecular or cellular interaction to be taken into account has been challenging for many decades. Two competing approaches have been the…

Cellular Automata and Lattice Gases · Physics 2017-11-13 Kátia K. Cassiano , Valmir C. Barbosa

Nature has always been an inspiration to researchers with its diversity and robustness of its systems, and Artificial Immune Systems are one of them. Many algorithms were inspired by ongoing discoveries of biological immune systems…

Networking and Internet Architecture · Computer Science 2014-03-13 Amira Sayed A. Aziz , Ahmad Taher Azar , Aboul Ella Hassanien , Sanaa El-Ola Hanafy