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The adaptive and innate branches of the vertebrate immune system work in close collaboration to protect organisms from harmful pathogens. As an organism ages its immune system undergoes immunosenescence, characterized by declined…

Tissues and Organs · Quantitative Biology 2020-08-28 Eric W. Jones , Jiming Sheng , Jean M. Carlson , Shenshen Wang

The contact process with an asymptomatic state, introduced in [Belhadji, Lanchier and Mercer, Stochastic Process. Appl., 176:104417, 2024], is a natural variant of the basic contact process that distinguishes between asymptomatic (state 1)…

Probability · Mathematics 2025-10-27 Nicolas Lanchier

I present three models of plant--pathogen interactions. The models are stochastic and spatially explicit at the scale of individual plants. For each model, I use a version of pair approximation or moment closure along with a separation of…

Numerical Analysis · Mathematics 2025-10-20 David H. Brown

We study the contact process running in the one-dimensional lattice undergoing dynamical percolation, where edges open at rate $vp$ and close at rate $v(1-p)$. Our goal is to explore how the speed of the environment, $v$, affects the…

Probability · Mathematics 2020-10-15 Amitai Linker , Daniel Remenik

We consider the contact process on a dynamic graph defined as a random $d$-regular graph with a stationary edge-switching dynamics. In this graph dynamics, independently of the contact process state, each pair $\{e_1,e_2\}$ of edges of the…

The spread of infectious disease and the evolution of antigenically distinct strains are often modeled separately, despite strong feedbacks mediated by host immune memory and heterogeneous contacts. To tackle this challenging problem, we…

Populations and Evolution · Quantitative Biology 2026-04-01 Davide Zanchetta , Vittoria Bettio , Sandro Azaele , Manlio De Domenico

We investigate the dynamics of a simple epidemiological model for the invasion by a pathogen strain of a population where another strain circulates. We assume that reinfection by the same strain is possible but occurs at a reduced rate due…

Populations and Evolution · Quantitative Biology 2007-05-23 A. Nunes , M. M. Telo da Gama , M. G. M. Gomes

We consider a two-type stochastic competition model on the integer lattice Z^d. The model describes the space evolution of two ``species'' competing for territory along their boundaries. Each site of the space may contain only one…

Probability · Mathematics 2007-05-23 George Kordzakhia , Steven P. Lalley

In order to understand the cost of a potentially high infectiousness of symptomatic individuals or, on the contrary, the benefit of social distancing, quarantine, etc. in the course of an infectious disease, this paper considers a natural…

Probability · Mathematics 2024-04-29 Lamia Belhadji , Nicolas Lanchier , Max Mercer

The forest of mutations associated to a multitype branching forest is obtained by merging together all vertices of its clusters and by preserving connections between them. We first show that the forest of mutations of any mulitype branching…

Probability · Mathematics 2015-10-06 Loïc Chaumont , Thi Ngoc Anh Nguyen

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

A tumor can be thought of as an ecosystem, which critically means that we cannot just consider it as a collection of mutated cells but more as a complex system of many interacting cellular and microenvironmental elements. At its simplest, a…

Populations and Evolution · Quantitative Biology 2013-05-03 Jill Gallaher , Alexander R. A. Anderson

Infectious diseases are practically represented by models with multiple states and complex transition rules corresponding to, for example, birth, death, infection, recovery, disease progression, and quarantine. In addition, networks…

Disordered Systems and Neural Networks · Physics 2007-05-23 Naoki Masuda , Norio Konno

We prove for the contact process on $Z^d$, and many other graphs, that the upper invariant measure dominates a homogeneous product measure with large density if the infection rate $\lambda$ is sufficiently large. As a consequence, this…

Probability · Mathematics 2015-06-26 Thomas Liggett , Jeffrey E. Steif

We propose a modelling framework to analyse the stochastic behaviour of heterogeneous, multi-scale cellular populations. We illustrate our methodology with a particular example in which we study a population with an oxygen-regulated…

Biological Physics · Physics 2017-09-01 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

What is aging? Mechanistic answers to this question remain elusive despite decades of research. Here, we propose a mathematical model of cellular aging based on a model gene interaction network. Our network model is made of only non-aging…

Molecular Networks · Quantitative Biology 2023-09-12 Hong Qin

We consider the contact process with infection rate $\lambda$ on $\mathbb{T}_n^d$, the $d$-ary tree of height $n$. We study the extinction time $\tau_{\mathbb{T}_n^d}$, that is, the random time it takes for the infection to disappear when…

Probability · Mathematics 2014-03-25 Michael Cranston , Thomas Mountford , Jean-Christophe Mourrat , Daniel Valesin

This article deals with the emergence of a specific mating preference pattern called homogamy in a population. Individuals are characterized by their genotype at two haploid loci, and the population dynamics is modelled by a non-linear…

Probability · Mathematics 2019-09-25 Coron Camille , Costa Manon , Laroche Fabien , Leman Hélène , Smadi Charline

We study the contact process with stirring on $\mathbb{Z}^d$. In this process, particles occupy vertices of $\mathbb{Z}^d$; each particle dies with rate 1 and generates a new particle at a randomly chosen neighboring vertex with rate…

Probability · Mathematics 2015-09-15 Anna Levit , Daniel Valesin

We study the contact process on a class of geometric random graphs with scale-free degree distribution, defined on a Poisson point process on $\mathbb{R}^d$. This class includes the age-dependent random connection model and the soft Boolean…

Probability · Mathematics 2024-04-19 Peter Gracar , Arne Grauer