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In this work we propose a novel method to calculate mean first-passage times (MFPTs) for random walks on graphs, based on a dimensionality reduction technique for Markov State Models, known as local-equilibrium (LE). We show that for a…

Statistical Mechanics · Physics 2022-03-09 Yanik-Pascal Förster , Luca Gamberi , Evan Tzanis , Pierpaolo Vivo , Alessia Annibale

We study translocation of semiflexible polymers driven by force $f_d$ inside a nanometer-scale pore using our three-dimensional Langevin dynamics model. We show that the translocation time $\tau$ increases with increasing bending rigidity…

Biological Physics · Physics 2018-06-27 Pauli M. Suhonen , Riku P. Linna

The transport of deformable particles through porous media underlies a wealth of applications ranging from filtration to oil recovery to the transport and spreading of biological agents. Using direct numerical simulations, we analyze the…

Soft Condensed Matter · Physics 2020-06-09 Brato Chakrabarti , Charles Gaillard , David Saintillan

We consider single particle and polymer translocation where the frictional properties experienced from the environment are changing in time. This work is motivated by the interesting frequency responsive behaviour observed when a polymer is…

Soft Condensed Matter · Physics 2012-12-06 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

We use a combination of computer simulations and iso-flux tension propagation (IFTP) theory to investigate translocation dynamics of a flexible linear polymer through a nanopore into an environment composed of repulsive active rods in 2D.…

Soft Condensed Matter · Physics 2021-02-03 Hamidreza Khalilian , Jalal Sarabadani , Tapio Ala-Nissila

The mean first-passage time (MFPT) for a Brownian particle to surmount a potential barrier of height $\Delta U$ is a fundamental quantity governing a wide array of physical and chemical processes. According to the Arrhenius Law, the MFPT…

Statistical Mechanics · Physics 2025-11-24 Vishwajeet Kumar , Ohad Shpielberg , Arnab Pal

We investigate numerically, using the bond-fluctuation model, the adsorption of many random AB--copolymers with excluded volume interactions at the interface between two solvents. We find two regimes, controlled by the total number of…

Soft Condensed Matter · Physics 2007-05-23 Gongwen Peng , Jens-Uwe Sommer , Alexander Blumen

A vast variety of real-life networks display the ubiquitous presence of scale-free phenomenon and small-world effect, both of which play a significant role in the dynamical processes running on networks. Although various dynamical processes…

Physics and Society · Physics 2009-07-19 Zhongzhi Zhang , Shuigeng Zhou , Wenlei Xie , Lichao Chen , Yuan Lin , Jihong Guan

Using analytical techniques and Langevin dynamics simulations, we investigate the dynamics of polymer translocation through a nanochannel embedded in two dimensions under an applied external field. We examine the translocation time for…

Soft Condensed Matter · Physics 2012-03-26 Huaisong Yong , Yilin Wang , Shichen Yuan , Bi Xu , Kaifu Luo

We investigate random walks on complex networks and derive an exact expression for the mean first passage time (MFPT) between two nodes. We introduce for each node the random walk centrality $C$, which is the ratio between its coordination…

Statistical Mechanics · Physics 2007-05-23 Jae Dong Noh , Heiko Rieger

Relatively general techniques for computing mean first-passage time (MFPT) of random walks on networks with a specific property are very useful, since a universal method for calculating MFPT on general graphs is not available because of…

Statistical Mechanics · Physics 2010-10-01 Yuan Lin , Bin Wu , Zhongzhi Zhang

We investigate the translocation dynamics of a folded linear polymer which is pulled through a nanopore by an external force. To this end, we generalize the iso-flux tension propagation (IFTP) theory for end-pulled polymer translocation to…

Soft Condensed Matter · Physics 2019-12-18 Bappa Ghosh , Jalal Sarabadani , Srabanti Chaudhury , Tapio Ala-Nissila

We study pore blockade times for a translocating polymer of length $N$, driven by a field $E$ across the pore in three dimensions. The polymer performs Rouse dynamics, i.e., we consider polymer dynamics in the absence of hydrodynamical…

Soft Condensed Matter · Physics 2008-02-15 Henk Vocks , Debabrata Panja , Gerard T. Barkema , Robin C. Ball

We derive an approximate but fully explicit formula for the mean first-passage time (MFPT) to a small absorbing target of arbitrary shape in a general elongated domain in the plane. Our approximation combines conformal mapping, boundary…

Statistical Mechanics · Physics 2021-10-14 Denis S. Grebenkov , Alexei T. Skvortsov

Previous work shows that the mean first-passage time (MFPT) for random walks to a given hub node (node with maximum degree) in uncorrelated random scale-free networks is closely related to the exponent $\gamma$ of power-law degree…

Statistical Mechanics · Physics 2010-11-12 Zhongzhi Zhang , Shuyang Gao , Wenlei Xie

We consider the passage of long polymers of length N through a hole in a membrane. If the process is slow, it is in principle possible to focus on the dynamics of the number of monomers s on one side of the membrane, assuming that the two…

Soft Condensed Matter · Physics 2009-11-10 Yacov Kantor , Mehran Kardar

We present scaling estimates for characteristic times $\tau_{\rm lin}$ and $\tau_{\rm br}$ of pulling ideal linear and randomly branched polymers of $N$ monomers into a small hole by a force $f$. We show that the absorbtion process develops…

Statistical Mechanics · Physics 2009-11-11 A. Y. Grosberg , S. Nechaev , M. Tamm , O. Vasilyev

In this paper we address the problem of the calculation of the mean first passage time (MFPT) on generic graphs. We focus in particular on the mean first passage time on a node 's' for a random walker starting from a generic, unknown, node…

Statistical Mechanics · Physics 2007-05-23 Andrea Baronchelli , Vittorio Loreto

Using fast off-lattice Monte Carlo simulations with experimentally accessible fluctuations, we report the first systematic study unambiguously quantifying the shift of the order-disorder transition (ODT) $\chi^*$ of symmetric diblock…

Soft Condensed Matter · Physics 2012-01-24 Jing Zong , Qiang Wang

The first passage is a generic concept for quantifying when a random quantity such as the position of a diffusing molecule or the value of a stock crosses a preset threshold (target) for the first time. The last decade saw an enlightening…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler