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Morphological transitions of phase separation associated with the asymmetry of lipid composition were investigated using micrometer-sized vesicles of lipid bilayers made from a lipid mixture. The complete macro-phase-separated morphology…

Biological Physics · Physics 2015-04-14 Shunsuke F. Shimobayashi , Masatoshi Ichikawa , Takashi Taniguchi

Amphiphilic lipid bilayers modify the friction properties of the surfaces on top of which they are deposited. In particular, the measured sliding friction coefficient is significantly reduced compared with the native surface. We investigate…

Biological Physics · Physics 2021-12-01 Othmène Benazieb , Claire Loison , Fabrice Thalmann

We investigate the phenomenon of protein induced tubulation of lipid bilayer membranes within a continuum framework using Monte Carlo simulations coupled with the Widom insertion technique to compute excess chemical potentials. Tubular…

Biological Physics · Physics 2015-10-13 Richard W. Tourdot , N. Ramakrishnan , Tobias Baumgart , Ravi Radhakrishnan

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

There is mounting evidence that lipid bilayers display conductive properties. However, when interpreting the electrical response of biological membranes to voltage changes, they are commonly considered as inert insulators. However, lipid…

Biological Physics · Physics 2022-11-24 Karis A. Zecchi , Thomas Heimburg

The response kinetics of liquid crystalline phosphatidylcholine bilayer stacks to rapid, IR-laser induced temperature jumps has been studied by millisecond time-resolved x-ray diffraction. The system reacts on the fast temperature change by…

Biological Physics · Physics 2007-05-23 Georg Pabst , Michael Rappolt , Heinz Amenitsch , Sigrid Bernstorff , Peter Laggner

Flow in thin films is highly dependent on the boundary conditions. Here, we study the capillary levelling of thin bilayer films composed of two immiscible liquids. Specifically, a stepped polymer layer is placed atop another, flat polymer…

Soft Condensed Matter · Physics 2021-01-27 Vincent Bertin , Carmen Lee , Thomas Salez , Elie Raphael , Kari Dalnoki-Veress

Giant unilamellar vesicles (GUVs) composed of as few as three lipid species can phase separate into small-scale lipid domains with stripes and dots patterns. These patterns have been experimentally characterized in terms of how their size…

Soft Condensed Matter · Physics 2025-05-21 Qiwei Yu , Andrej Košmrlj

We investigate the effect of an applied electric potential on the mechanics of a coarse grained POPC bilayer under tension. The size and duration of our simulations allow for a detailed and accurate study of the fluctuations. Effects on the…

Chemical Physics · Physics 2013-11-11 Bastien Loubet , Michael Andersen Lomholt , Himanshu Khandelia

We discuss the hydrodynamic collective effects due to active protein molecules that are immersed in lipid bilayer membranes and modeled as stochastic force dipoles. We specifically take into account the presence of the bulk solvent which…

Soft Condensed Matter · Physics 2017-05-24 Yuto Hosaka , Kento Yasuda , Ryuichi Okamoto , Shigeyuki Komura

Biological membranes are dynamic surfaces whose shape and function are critically influenced by protein inclusions (PIs). While membrane deformations induced by PIs have been extensively studied in the small-deformation regime, a variety of…

Biological Physics · Physics 2026-01-23 Gaetano Ferraro , Michele Castellana

Partial localization is the phenomenon of self-aggregation of mass into high-density structures that are thin in one direction and extended in the others. We give a detailed study of an energy functional that arises in a simplified model…

Mathematical Physics · Physics 2007-05-23 Mark A. Peletier , Matthias Roeger

A thin circular elastic sheet floating on a drop-like liquid substrate is deformed due to incompatibility between the curved substrate and the planar sheet. We adopt a variational viewpoint by minimizing the non-convex membrane energy…

Analysis of PDEs · Mathematics 2026-02-19 Peter Bella , Carlos Román

We present a stochastic phase-field model for multicomponent lipid bilayers that explicitly accounts for the quasi-two-dimensional hydrodynamic environment unique to a thin fluid membrane immersed in aqueous solution. Dynamics over a wide…

Soft Condensed Matter · Physics 2011-05-26 Brian A. Camley , Frank L. H. Brown

Random lateral translocation of lipids and proteins is a universal process on membrane surfaces. Local aggregation or organization of lipids and proteins can be induced when this lateral random diffusion is mediated by the electrostatic…

Quantitative Methods · Quantitative Biology 2015-06-03 Y. C. Zhou

Liquid water is not only of obvious importance but also extremely intriguing, displaying many anomalies that still challenge our understanding of such an a priori simple system. The same is true when looking at nanoconfined water: The…

Soft Condensed Matter · Physics 2016-06-29 Jon Zubeltzu , Fabiano Corsetti , M. V. Fernandez-Serra , Emilio Artacho

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

Curvature in biological membranes can be generated by a variety of different molecular mechanisms such as protein scaffolding, lipid or protein asymmetry, cytoskeletal forces, etc. These mechanisms have the net effect of generating stresses…

Multicomponent bilayer structures arise as the ubiquitous plasma membrane in cellular biology and as blends of amphiphilic copolymers used in electrolyte membranes, drug delivery, and emulsion stabilization within the context of synthetic…

Analysis of PDEs · Mathematics 2015-12-22 Keith Promislow , Qiliang Wu

A microscopic model of a surface polymer network - membrane system is introduced, with contact polymer surface interactions that can be either repulsive or attractive and sliplinks of functionality four randomly distributed over the…

Condensed Matter · Physics 2016-08-31 R. Podgornik