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The purpose of this paper is to study the shapes and stabilities of bio-membranes within the framework of exterior differential forms. After a brief review of the current status in theoretical and experimental studies on the shapes of…

Soft Condensed Matter · Physics 2007-05-23 Z. C. Tu , Z. C. Ou-Yang

We use computer simulations and a simple free energy model to study the response of a bilayer membrane to the application of a negative (compressive) mechanical tension. Such a tension destabilizes the long wavelength undulation modes of…

Soft Condensed Matter · Physics 2015-06-24 Yotam Y. Avital , Oded Farago

The impact of confinement on self-assembly of particles interacting with short-range attraction and long-range repulsion (SALR) potential is studied for thermodynamic states corresponding to local ordering of clusters or layers in the bulk.…

Soft Condensed Matter · Physics 2014-11-17 Jakub Pękalski , Alina Ciach , Noé G. Almarza

We study diffusion coefficients of liquid domains by explicitly taking into account the two-layered structure called leaflets of the bilayer membrane. In general, the velocity fields associated with each leaflet are different and the layers…

Soft Condensed Matter · Physics 2015-06-18 Kazuhiko Seki , Saurabh Mogre , Shigeyuki Komura

We propose a model that accounts for the budding transition of asymmetric two-component lipid domains, where the two monolayers (leaflets) have different average compositions controlled by independent chemical potentials. Assuming a…

Soft Condensed Matter · Physics 2016-09-16 Jean Wolff , Shigeyuki Komura , David Andelman

The outstanding lubrication of articular cartilage in the major synovial joints such as hips and knees, essential for the joint well-being, has been attributed to boundary layers of lipids at the outer cartilage surfaces, which have very…

Soft Condensed Matter · Physics 2024-04-10 Di Jin , Jacob Klein

Using molecular dynamics, this study investigates the local elastic properties of transverse shear deformation of lipid membranes. The analysis demonstrates that transverse shear deformation induces anisotropy in the local stress profile of…

Soft Condensed Matter · Physics 2025-11-12 Konstantin V. Pinigin

Spatially confined rigid membranes reorganize their morphology in response to the imposed constraints. A crumpled elastic sheet presents a complex pattern of random folds focusing the deformation energy while compressing a membrane resting…

Tissue fluidity regulates many critical biological processes, including embryonic development, wound healing, and cancer metastasis. In confluent epithelia, where cell packing fraction is effectively fixed, the prevailing paradigm…

Biological Physics · Physics 2026-03-09 Pradip K. Bera , Anh Q. Nguyen , Molly McCord , Dapeng Bi , Jacob Notbohm

The supramolecular assembly of lipids into bilayer membranes is essential for cellular structure and function. However, the impact of lipid structural variations such as acyl chain length, degree of unsaturation, and headgroup type on…

Soft Condensed Matter · Physics 2024-12-13 Sonam Phuntsho

Lipid bilayer membranes are not uniform and clusters of lipids in a more ordered state exist within the generally disorder lipid milieu of the membrane. These clusters of ordered lipids microdomains are now referred to as lipid rafts.…

Quantitative Methods · Quantitative Biology 2017-06-28 Melissa R. Adkins , Y. C. Zhou

Self-consistent field theory is used to determine structural and energetic properties of metastable intermediates and unstable transition states involved in the standard stalk mechanism of bilayer membrane fusion. A microscopic model of…

Soft Condensed Matter · Physics 2016-08-31 Kirill Katsov , Marcus Mueller , Michael Schick

Periodic wrinkling of a rigid capping layer on a deformable substrate provides a useful method for templating surface topography for a variety of novel applications. Many experiments have studied wrinkle formation during the compression of…

Soft Condensed Matter · Physics 2020-04-21 John F. Niven , Gurkaran Chowdhry , James S. Sharp , Kari Dalnoki-Veress

In this work, we present a mathematical and computational framework to model the dynamics of open lipid bilayer membranes interacting with ambient Stokes flow. The model explicitly couples the three-dimensional viscous fluid, the…

Numerical Analysis · Mathematics 2026-01-21 Han Zhou , Yuan-Nan Young , Yoichiro Mori

Highly oriented solid-supported lipid membranes in stacks of controlled number $N \simeq 16$ (oligo-membranes) have been prepared by spin-coating using the uncharged lipid model system 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). The…

Soft Condensed Matter · Physics 2015-04-10 Ulrike Mennicke , Doru Constantin , Tim Salditt

We study a model of a lipid bilayer membrane described by two order parameters: the chemical composition described using the Gaussian model and the spatial configuration described with the elastic deformation model of a membrane with a…

Soft Condensed Matter · Physics 2022-06-08 Piotr Nowakowski , Bernd Henning Stumpf , Ana-Sunčana Smith , Anna Maciołek

We report diffusion coeffcients of micron-scale liquid domains in giant unilamellar vesicles of phospholipids and cholesterol. The trajectory of each domain is tracked, and the mean square displacement grows linearly in time as expected for…

Soft Condensed Matter · Physics 2007-05-23 Pietro Cicuta , Sarah L. Keller , Sarah L. Veatch

Nanoindentation of bilayer graphene is studied using molecular dynamics simulations. We compared our simulation results with those from elasticity theory as based on the nonlinear F\"{o}ppl-Hencky equations with rigid boundary condition.…

Mesoscale and Nanoscale Physics · Physics 2015-05-28 M. Neek-Amal , F. M. Peeters

Monodisperse suspensions of rodlike chiral $fd$ viruses are condensed into a rod-length thick colloidal monolayers of aligned rods by depletion forces. Twist deformations of the molecules are expelled to the monolayer edge as in a chiral…

Soft Condensed Matter · Physics 2014-03-26 C. Nadir Kaplan , Robert B. Meyer

Wrinkling, creasing and folding are frequent phenomena encountered in biological and man-made bilayers made by thin films bonded to thicker and softer substrates often containing fibers. Paradigmatic examples of the latter are the skin, the…

Soft Condensed Matter · Physics 2024-01-23 A. Mirandola , A. Cutolo , A. R. Carotenuto , N. Nguyen , L. Pocivavsek , M. Fraldi , L. Deseri