English

Dynamic simulations of multicomponent lipid membranes over long length and time scales

Soft Condensed Matter 2011-05-26 v1

Abstract

We present a stochastic phase-field model for multicomponent lipid bilayers that explicitly accounts for the quasi-two-dimensional hydrodynamic environment unique to a thin fluid membrane immersed in aqueous solution. Dynamics over a wide range of length scales (from nanometers to microns) for durations up to seconds and longer are readily accessed and provide a direct comparison to fluorescence microscopy measurements in ternary lipid/cholesterol mixtures. Simulations of phase separation kinetics agree with experiment and elucidate the importance of hydrodynamics in the coarsening process.

Keywords

Cite

@article{arxiv.1105.4898,
  title  = {Dynamic simulations of multicomponent lipid membranes over long length and time scales},
  author = {Brian A. Camley and Frank L. H. Brown},
  journal= {arXiv preprint arXiv:1105.4898},
  year   = {2011}
}