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Related papers: Chromatin dynamics: Nucleosomes go mobile through …

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Nucleic acids have been regarded as stiff polymers with long-range flexibility and generally modeled using elastic rod models of polymer physics. Notwithstanding, investigations carried out over the past few years on single fragments of…

Soft Condensed Matter · Physics 2025-05-09 Marco Zoli

We present a statistical-mechanical analysis of the positioning of nucleosomes along one of the chromosomes of yeast DNA as a function of the strength of the binding potential and of the chemical potential of the nucleosomes. We find a…

Soft Condensed Matter · Physics 2009-11-13 David J. Schwab , Robijn F. Bruinsma , Joseph Rudnick , Jonathan Widom

Amoeboid cell migration is characterized by frequent changes of the direction of motion and resembles a persistent random walk on long time scales. Although it is well known that cell migration is typically driven by the actin cytoskeleton,…

Biological Physics · Physics 2021-06-09 Nicolas Ecker , Karsten Kruse

We review statistical-mechanical theories of single-molecule micromanipulation experiments on nucleic acids. First, models for describing polymer elasticity are introduced. We then review how these models are used to interpret…

Soft Condensed Matter · Physics 2007-05-23 S. Cocco , J. F. Marko , R. Monasson

In the nuclei of eukaryotic cells, DNA is packaged through several levels of compaction in an orderly retrievable way that enables the correct regulation of gene expression. The functional dynamics of this assembly involves the unwinding of…

Subcellular Processes · Quantitative Biology 2007-05-23 Maria Barbi , Julien Mozziconacci , Jean-Marc Victor

Observations of single epidermal cells on flat adhesive substrates have revealed two distinct morphological and functional states, namely a non-migrating symmetric unpolarized state and a migrating asymmetric polarized state. These states…

Biological Physics · Physics 2010-04-14 Wolfgang Alt , Martin Bock , Christoph Möhl

Self-propelled particles move along circles rather than along a straight line when their driving force does not coincide with their propagation direction. Examples include confined bacteria and spermatozoa, catalytically driven nanorods,…

Soft Condensed Matter · Physics 2008-08-18 Sven van Teeffelen , Hartmut Löwen

Chromatin is a highly compact and dynamic nuclear structure that consists of DNA and associated proteins. The main organizational unit is the nucleosome, which consists of a histone octamer with DNA wrapped around it. Histone proteins are…

Genomics · Quantitative Biology 2013-09-30 Veit Schwämmle , Ole Nørregaard Jensen

In this paper we have investigated, through computer simulations, dislocation nucleation and dislocation dynamics in a heterostructure system with the lattice-mismatch interface, i.e. a system with internal strain. In particular, we have…

Materials Science · Physics 2018-04-20 Marco Patriarca , Antti Kuronen , Kimmo Kaski

In this paper, we investigate mechanical motion of ultra-slow single atoms considering each atom is coherently coupled to a traveling-wave light. The main noise in this system is originated from Doppler broadening due to the continuous…

Quantum Physics · Physics 2023-03-29 Wenxi Lai

By observing reconstituted chromatin by fluorescence microscopy (FM) and atomic force microscopy (AFM), we found that the density of nucleosomes exhibits a bimodal profile, i.e., there is a large transition between the dense and dispersed…

Subcellular Processes · Quantitative Biology 2015-06-26 Tonau Nakai , Kohji Hizume , Shige. H. Yoshimura , Kunio Takeyasu , Kenichi Yoshikawa

The interplay between bending of the molecule axis and appearance of disruptions in circular DNA molecules, with $\sim 100$ base pairs, is addressed. Three minicircles with different radii and almost equal content of AT and GC pairs are…

Soft Condensed Matter · Physics 2014-06-03 Marco Zoli

The origin of biological motion can be traced back to the function of molecular motor proteins. Cytoplasmic dynein and kinesin transport organelles within our cells moving along a polymeric filament, the microtubule. The motion of the…

Statistical Mechanics · Physics 2015-06-25 Imre Derenyi , Tamas Vicsek

A propagating "beam" triggering a local phase transition in a nematic elastomer sets it into a crawling motion, which may morph due to buckling. We consider the motion of the various configurations of slender rods and thin stripes with both…

Biological Physics · Physics 2016-03-23 A. P. Zakharov , L. M. Pismen

A simple model of DNA based on two interacting polymers has been used to study the unzipping of a double stranded DNA subjected to a periodic force. We propose a dynamical transition, where without changing the physiological condition, it…

Biological Physics · Physics 2015-06-11 Sanjay Kumar , Garima Mishra

Using both atomistic and particle-based simulations, we investigate the current-driven dynamics of skyrmions on two-dimensional periodic substrates when there are multiple skyrmions per substrate minimum. At zero drive, the system forms…

Mesoscale and Nanoscale Physics · Physics 2025-04-03 J. C. Bellizotti Souza , C. J. O. Reichhardt , C. Reichhardt , N. P. Vizarim , P. A. Venegas

Recent single molecule experiments probing the passage process of a short single-stranded DNA (ssDNA) through a membrane channel (translocation) allow to measure the passage time distribution. Building on a recent modelling approach (D. K.…

Statistical Mechanics · Physics 2009-11-10 Ralf Metzler , Joseph Klafter

We investigate the kinetics of the DNA melting transition using modified versions of the Peyrard-Dauxois-Bishop and Poland-Scheraga models that include long and short range interactions. Using Brownian dynamics and Monte Carlo simulations,…

Other Condensed Matter · Physics 2007-05-23 Aaron Santos , William Klein

We study the dynamics of local bond orientation in regular hyperbranched polymers modeled by Vicsek fractals. The local dynamics is investigated through the temporal autocorrelation functions of single bonds and the corresponding relaxation…

Soft Condensed Matter · Physics 2016-07-26 Maxim Dolgushev , Denis A. Markelov , Florian Fürstenberg , Thomas Guérin

Deformations of single-wall carbon nanotubes are investigated within the tight-binding model with deformation-dependent hopping energies. We show that the nanotubes tend to twist and shrink spontaneously at zero temperature. The explicit…

Mesoscale and Nanoscale Physics · Physics 2017-07-05 Vít Jakubský , Axel Pérez-Obiol