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Related papers: Critical dynamics of DNA denaturation

200 papers

DNA has a well-defined structural transition -- the denaturation of its double-stranded form into two single strands -- that strongly affects its thermal transport properties. We show that, according to a widely implemented model for DNA…

Soft Condensed Matter · Physics 2013-02-12 Chih-Chun Chien , Kirill A. Velizhanin , Yonatan Dubi , Michael Zwolak

We report model calculations on DNA single strands which describe the equilibrium dynamics and kinetics of hairpin formation and melting. Modeling is at the level of single bases. Strand rigidity is described in terms of simple polymer…

Soft Condensed Matter · Physics 2007-10-01 Jalal Errami , Michel Peyrard , Nikos Theodorakopoulos

We performed molecular dynamics simulations to study relaxation phenomena during vapor-liquid transitions in a single component Lennard-Jones system. Results from two different overall densities are presented; one in the neighborhood of the…

Statistical Mechanics · Physics 2019-06-04 Sutapa Roy , Arabinda Bera , Suman Majumder , Subir K. Das

We study the dynamics of denaturation bubbles in double-stranded DNA on the basis of the Poland-Scheraga model. We show that long time distributions for the survival of DNA bubbles and the size autocorrelation function can be derived from…

Statistical Mechanics · Physics 2008-06-02 Hans C. Fogedby , Ralf Metzler

A simple Langevin approach is used to study stationary properties of the Peyrard-Bishop-Dauxois model for DNA, allowing known properties to be recovered in an easy way. Results are shown for the denaturation transition in homogeneous…

Soft Condensed Matter · Physics 2009-11-13 Francisco de los Santos , Omar Al Hammal , Miguel Angel Munoz

We show that a mesoscale model, with a minimal number of parameters, can well describe the thermomechanical and mechanochemical behavior of homogeneous DNA at thermal equilibrium under tension and torque. We predict critical temperatures…

Biomolecules · Quantitative Biology 2015-06-22 Cristiano Nisoli , A. R. Bishop

Many thermodynamic instabilities in one dimension (e.g. DNA thermal denaturation, wetting of interfaces) can be described in terms of simple models involving harmonic coupling between nearest neighbors and an asymmetric on-site potential…

Statistical Mechanics · Physics 2015-06-24 Thierry Dauxois , Nikos Theodorakopoulos , Michel Peyrard

We study the thermodynamic and dynamic behaviors of twist-induced denaturation bubbles in a long, stretched random sequence of DNA. The small bubbles associated with weak twist are delocalized. Above a threshold torque, the bubbles of…

Statistical Mechanics · Physics 2016-08-31 Terence Hwa , Enzo Marinari , Kim Sneppen , Lei-han Tang

We study the large amplitude response of classical molecules to electromagnetic radiation, showing the universality of the transition from the linear to nonlinear response and brakeup at sufficiently large amplitudes. A range of models,…

Applied Physics · Physics 2020-07-01 V. R. Gabriele , A. Shvonski , C. S. Hoffman , M. Giersig , A. Herczynski , M. J. Naughton , K. Kempa

We study theoretically the mechanical failure of a simple model of double stranded DNA under an applied shear. Starting from a more microscopic Hamiltonian that describes a sheared DNA, we arrive at a nonlinear generalization of a ladder…

Soft Condensed Matter · Physics 2009-04-13 Buddhapriya Chakrabarti , David R. Nelson

This article investigates the effect for random pinning models of long range power-law decaying correlations in the environment. For a particular type of environment based on a renewal construction, we are able to sharply describe the phase…

Probability · Mathematics 2025-08-15 Quentin Berger , Hubert Lacoin

We present a nonlinear dynamical model for DNA thermal denaturation, which is based on the finite stacking enthalpies used in thermodynamical nearest-neighbour calculations. Within this model, the finiteness of stacking enthalpies is shown…

Biological Physics · Physics 2007-05-23 Marc Joyeux , Sahin Buyukdagli

We address the question of the quantitative relationship between thermodynamic phase transitions and topological changes in the potential energy manifold analyzing two classes of one dimensional models, the Burkhardt solid-on-solid model…

Statistical Mechanics · Physics 2009-11-11 L. Angelani , G. Ruocco , F. Zamponi

The denaturation transition which takes place in circular DNA is analyzed by extending the Poland-Scheraga model to include the winding degrees of freedom. We consider the case of a homopolymer whereby the winding number of the double…

Statistical Mechanics · Physics 2011-11-22 Amir Bar , Alkan Kabakçıoğlu , David Mukamel

One-dimensional thermodynamic instabilities are phase transitions not prohibited by Landau's argument, because the energy of the domain wall (DW) which separates the two phases is infinite. Whether they actually occur in a given system of…

Statistical Mechanics · Physics 2007-06-17 Nikos Theodorakopoulos

We propose a model for the fluctuation dynamics of the local denaturation zones (bubbles) in double-stranded DNA. In our formulation, the DNA strand is model as a one dimensional Rouse chain confined at both the ends. The bubble is formed…

Soft Condensed Matter · Physics 2014-06-25 Rajarshi Chakrabarti

The denaturation dynamics of a long double-stranded DNA is studied by means of a model of the Poland-Scheraga type. We note that the linking of the two strands is a locally conserved quantity, hence we introduce local updates that respect…

Statistical Mechanics · Physics 2009-01-28 Marco Baiesi , Roberto Livi

We use a master equation approach based on the Poland-Scheraga free energy for DNA denaturation to investigate the (un)zipping dynamics of a denaturation wedge in a stretch of DNA, that is clamped at one end. In particular, we quantify the…

Soft Condensed Matter · Physics 2009-11-11 Tobias Ambjoernsson , Ralf Metzler

Circular double stranded DNA has different topological states which are defined by their linking numbers. Equilibrium distribution of linking numbers can be obtained by closing a linear DNA into a circle by ligase. Using Monte Carlo…

Biomolecules · Quantitative Biology 2009-05-04 Hu Chen , Yanhui Liu , Zhen Zhou , Lin Hu , Zhong-Can Ou-Yang , Jie Yan

A study of the micromechanical unzipping of DNA in the framework of the Peyrard-Bishop-Dauxois model is presented. We introduce a Monte Carlo technique that allows accurate determination of the dependence of the unzipping forces on…

Soft Condensed Matter · Physics 2007-05-23 N. K. Voulgarakis , A. Redondo , A. R. Bishop , K. O. Rasmussen