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The evolution of the scanning modules for scanning transmission electron microscopes (STEM) has realized the possibility to generate arbitrary scan pathways, an approach currently explored to improve acquisition speed and to reduce electron…

Images are formed by counting how many photons traveling from a given set of directions hit an image sensor during a given time interval. When photons are few and far in between, the concept of `image' breaks down and it is best to consider…

Computer Vision and Pattern Recognition · Computer Science 2016-10-04 Bo Chen , Pietro Perona

Hyperspectral (HS) imaging presents itself as a non-contact, non-ionizing and non-invasive technique, proven to be suitable for medical diagnosis. However, the volume of information contained in these images makes difficult providing the…

This paper introduces the concept of on-chip temporal optical computing, based on dispersive Fourier transform and suitably designed modulation module, to perform mathematical operations of interest, such as differentiation, integration, or…

Optics · Physics 2017-12-19 Hossein Babashah , Zahra Kavehvash , Amin Khavasi , Somayyeh Koohi

Intelligent medical diagnosis has shown remarkable progress based on the large-scale datasets with precise annotations. However, fewer labeled images are available due to significantly expensive cost for annotating data by experts. To fully…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Wentao Lei , Lei Liu , Li Liu

Microwave photonics is a remarkably powerful system for quantum simulation and technologies, but its integration in superconducting circuits, superior in many aspects, is constrained by the long wavelengths and impedance mismatches in this…

Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

Optics · Physics 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Spatial transcriptomics (ST) enables the visualization of gene expression within the context of tissue morphology. This emerging discipline has the potential to serve as a foundation for developing tools to design precision medicines.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Shivam Kumar , Samrat Chatterjee

The discovery and understanding of many ultrafast dynamical processes are often invaluable. This paper is the first report to apply optical parametric amplification to implement single-shot ultrafast imaging with high space and time…

Frame sampling is a fundamental component in video understanding and video--language model pipelines, yet evaluating the quality of sampled frames remains challenging. Existing evaluation metrics primarily focus on perceptual quality or…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Shih-Yao Lin

High-speed signal processing is essential for maximizing data throughput in emerging communication applications, like multiple-input multiple-output (MIMO) systems and radio-frequency (RF) interference cancellation. However, as these…

Photonic integrated circuits are gaining traction in the field of telecommunications and information processing for their low-loss and high-throughput data transmission in comparison to electronic integrated circuits. However, they are…

Optics · Physics 2025-08-08 Fahmy Yousry , Panu Hildén , Radoslaw Kolkowski , Andriy Shevchenko

Spike camera, a type of neuromorphic sensor with high-temporal resolution, shows great promise for high-speed visual tasks. Unlike traditional cameras, spike camera continuously accumulates photons and fires asynchronous spike streams. Due…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Liwen Hu , Yang Li , Mianzhi Liu , Yijia Guo , Shenghao Xie , Ziluo Ding , Tiejun Huang , Lei Ma

Recent developments in stimulated emission depletion (STED) microscopy achieved nanometer scale resolution and showed great potential in live cell imaging. Yet, STED nanoscopy techniques are based on single point-scanning. This constitutes…

Biological Physics · Physics 2015-06-16 Bin Yang , Frédéric Przybilla , Michael Mestre , Jean-Baptiste Trebbia , Brahim Lounis

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

Microfluidic Live-Cell Imaging (MLCI) generates high-quality data that allows biotechnologists to study cellular growth dynamics in detail. However, obtaining these continuous data over extended periods is challenging, particularly in…

Droplet microfluidics offers a versatile platform for analyzing liquid samples. Despite its potential, there is a lack of techniques that allow to reliably probe individual circulating droplets. The prospect of combining droplet…

Quantitative Methods · Quantitative Biology 2024-03-08 Marc Sulliger , Jaime Ortega Arroyo , Romain Quidant

We report the first characterization results of an optical time-stamping camera based on the Timepix4 chip coupled to a fully depleted optical silicon sensor and fast image intensifier, enabling sub-nanosecond scale, time-resolved imaging…

Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

Medical Physics · Physics 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

Modern lens designs are capable of resolving >10 gigapixels, while advances in camera frame-rate and hyperspectral imaging have made Terapixel/s data acquisition a real possibility. The main bottlenecks preventing such high data-rate…

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