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Intraoperative optical imaging is essential for surgical precision and patient safety, but current systems present anatomical and fluorescence information separately, causing delays and increasing cognitive load. A unified system for…

Medical Physics · Physics 2025-09-22 Kyriakos Pentarakis , George Kakavelakis , Constantinos Petridis , George Themelis

The advent of neuralmorphic spike cameras has garnered significant attention for their ability to capture continuous motion with unparalleled temporal resolution.However, this imaging attribute necessitates considerable resources for binary…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Kexiang Feng , Chuanmin Jia , Siwei Ma , Wen Gao

Recently three-dimensional (3D) imaging achieves tremendous success in consumer and industrial manufacturing. However, current 3D imaging methods rarely observe dynamical events happening in a short time interval due to the imaging speed…

Optics · Physics 2019-01-15 Jiajie Teng , Qiang Guo , Minghua Chen , Sigang Yang , Hongwei Chen

The conversion of phase variations in an optical wavefield into intensity information is of fundamental importance for optical imaging technology including microscopy of biological cells. While conventional approaches to phase-imaging…

Optics · Physics 2022-09-07 Lukas Wesemann , Jon Rickett , Timothy J. Davis , Ann Roberts

Measurements of microscale surface patterns are essential for process and quality control in industries across semiconductors, micro-machining, and biomedicines. However, the development of miniaturized and intelligent profiling systems…

The transmission electron microscope facilitates the highest-resolution imaging of any instrument ever created, and its limiting factor is no longer spatial resolution but dose efficiency. Low electron doses avoid sample damage but produce…

Machine Learning · Computer Science 2026-05-08 Georgia Channing , Debora Keller , Marta D. Rossell , Philip Torr , Stig Helveg , Henrik Eliasson

We describe a scheme into which a camera is turned into an efficient tunable frequency filter of a few Hertz bandwidth in an off-axis, heterodyne optical mixing configuration, enabling to perform parallel, high-resolution coherent spectral…

Optics · Physics 2009-09-01 Michael Atlan , Michel Gross

Recently, a novel bio-inspired spike camera has been proposed, which continuously accumulates luminance intensity and fires spikes while the dispatch threshold is reached. Compared to the conventional frame-based cameras and the emerging…

Multimedia · Computer Science 2019-12-23 Siwei Dong , Lin Zhu , Daoyuan Xu , Yonghong Tian , Tiejun Huang

Lightwave-driven scanning tunnelling microscopy (STM) at near-IR frequencies promises an unprecedented combination of atomic spatial resolution and temporal resolution approaching the attosecond range. To achieve this goal, high-sensitivity…

The detection of ultrafast optical and radio-frequency (RF) signals is crucial for applications ranging from high-speed communications to advanced sensing. However, conventional detectors are fundamentally constrained by their intrinsic…

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller

We present the development and validation of a novel multimodal optical imaging platform that integrates hyperspectral imaging (HSI) and laser speckle contrast imaging (LSCI) to enable real-time, non-invasive mapping of tissue oxygenation,…

Cell segmentation for multi-modal microscopy images remains a challenge due to the complex textures, patterns, and cell shapes in these images. To tackle the problem, we first develop an automatic cell classification pipeline to label the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Wei Lou , Xinyi Yu , Chenyu Liu , Xiang Wan , Guanbin Li , Siqi Liu , Haofeng Li

Ultrafast, high quantum efficiency single photon detectors are among the most sought-after elements in modern quantum optics and quantum communication. High photon detection efficiency is essential for scalable measurement-based quantum…

Optics · Physics 2015-05-30 W. Pernice , C. Schuck , O. Minaeva , M. Li , G. N. Goltsman , A. V. Sergienko , H. X. Tang

We propose a quantum information processing platform that utilizes the ultrafast time-bin encoding of photons. This approach offers a pathway to scalability by leveraging the inherent phase stability of collinear temporal interferometric…

Rapid, comprehensive, and accurate cell phenotyping without compromising viability, is crucial to many important biomedical applications, including stem-cell therapy, drug screening, and liquid biopsy. Typical image cytometry methods…

We report the implementation of a fully on-chip, lensless microscopy technique termed optofluidic ptychography. This imaging modality complements the miniaturization provided by microfluidics and allows the integration of ptychographic…

Instrumentation and Detectors · Physics 2021-12-21 Pengming Song , Chengfei Guo , Shaowei Jiang , Tianbo Wang , Patrick Hu , Derek Hu , Zibang Zhang , Bin Feng , Guoan Zheng

Existing learning-based stereo image codec adopt sophisticated transformation with simple entropy models derived from single image codecs to encode latent representations. However, those entropy models struggle to effectively capture the…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Xinjie Zhang , Shenyuan Gao , Zhening Liu , Jiawei Shao , Xingtong Ge , Dailan He , Tongda Xu , Yan Wang , Jun Zhang

Label-free imaging of rapidly moving, sub-diffraction sized structures has important applications in both biology and material science, as it removes the limitations associated with fluorescence tagging. However, unlabeled nanoscale…

The rapid growth of brain-inspired computing coupled with the inefficiencies in the CMOS implementations of neuromrphic systems has led to intense exploration of efficient hardware implementations of the functional units of the brain,…

Emerging Technologies · Computer Science 2018-08-29 Indranil Chakraborty , Gobinda Saha , Abhronil Sengupta , Kaushik Roy