Related papers: Uncertainty Reasoning with Large Language Models f…

Large language models (LLMs) show promise in medical diagnosis, but real-world deployment remains challenging due to high-stakes clinical decisions and imperfect reasoning reliability. As a result, careful inspection of model behavior is…

With the rapid advancement of large language models (LLMs), natural language processing (NLP) has achieved remarkable progress. Nonetheless, significant challenges remain in handling texts with ambiguity, polysemy, or uncertainty. We…

The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific…

Large language models (LLMs) exhibit remarkable capabilities on not just language tasks, but also various tasks that are not linguistic in nature, such as logical reasoning and social inference. In the human brain, neuroscience has…

Medical vision-language models (VLMs) show strong performance on radiology tasks but often produce fluent yet weakly grounded conclusions due to over-reliance on a dominant modality. We introduce a context-aligned reasoning framework that…

Large language models (LLMs) exhibit extensive medical knowledge but are prone to hallucinations and inaccurate citations, which pose a challenge to their clinical adoption and regulatory compliance. Current methods, such as Retrieval…

Rare diseases affect hundreds of millions worldwide, yet diagnosis often spans years. Convectional pipelines decouple noisy evidence extraction from downstream inferential diagnosis, and general/medical large language models (LLMs) face…

The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize…

Logical reasoning, i.e., deductively inferring the truth value of a conclusion from a set of premises, is an important task for artificial intelligence with wide potential impacts on science, mathematics, and society. While many…

Large Language Models (LLMs) have exhibited remarkable potential across a wide array of reasoning tasks, including logical reasoning. Although massive efforts have been made to empower the logical reasoning ability of LLMs via external…

Building trustworthy clinical AI systems requires not only accurate predictions but also transparent, biologically grounded explanations. We present \texttt{DiagnoLLM}, a hybrid framework that integrates Bayesian deconvolution, eQTL-guided…

Large Language Models (LLMs) often struggle with complex mathematical reasoning, where prose-based generation leads to unverified and arithmetically unsound solutions. Current prompting strategies like Chain of Thought still operate within…

Interpretability remains a key challenge for deploying large language models (LLMs) in clinical settings such as Alzheimer's disease progression diagnosis, where early and trustworthy predictions are essential. Existing attribution methods…

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Understanding why a large language model (LLM) is uncertain about the response is important for their reliable deployment. Current approaches, which either provide a single uncertainty score or rely on the classical aleatoric-epistemic…

In recent years, large language models (LLMs) have made significant advancements in developing human-like and engaging dialogue systems. However, in tasks such as consensus-building and persuasion, LLMs often struggle to resolve conflicts…

Mathematical reasoning is essential for problem-solving in education, science, and industry, serving as a crucial benchmark for evaluating artificial intelligence systems. As Large Language Models (LLMs) improve their reasoning…

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

Neuro-symbolic reasoning increasingly demands frameworks that unite the formal rigor of logic with the interpretability of large language models (LLMs). We introduce an end to end explainability by construction pipeline integrating the…