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Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

Natural language explanations represent a proxy for evaluating explanation-based and multi-step Natural Language Inference (NLI) models. However, assessing the validity of explanations for NLI is challenging as it typically involves the…

Computation and Language · Computer Science 2024-10-14 Xin Quan , Marco Valentino , Louise A. Dennis , André Freitas

The paper introduces a framework for the evaluation of the encoding of factual scientific knowledge, designed to streamline the manual evaluation process typically conducted by domain experts. Inferring over and extracting information from…

Computation and Language · Computer Science 2024-10-21 Magdalena Wysocka , Oskar Wysocki , Maxime Delmas , Vincent Mutel , Andre Freitas

Large language models (LLMs) have demonstrated strong potential in long-horizon decision-making tasks, such as embodied manipulation and web interaction. However, agents frequently struggle with endless trial-and-error loops or deviate from…

Artificial Intelligence · Computer Science 2026-04-06 Bin Wen , Ruoxuan Zhang , Yang Chen , Hongxia Xie , Lan-Zhe Guo

The trade-off between expressiveness and interpretability remains a core challenge when building human-centric predictive models for classification and decision-making. While symbolic rules offer interpretability, they often lack…

Artificial Intelligence · Computer Science 2024-06-26 Ruochen Wang , Si Si , Felix Yu , Dorothea Wiesmann , Cho-Jui Hsieh , Inderjit Dhillon

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

While large language models (LLMs) are increasingly being explored for mental health applications, recent studies reveal that they can exhibit stigma toward individuals with psychological conditions. Existing evaluations of this stigma…

Two lines of approaches are adopted for complex reasoning with LLMs. One line of work prompts LLMs with various reasoning structures, while the structural outputs can be naturally regarded as intermediate reasoning steps. Another line of…

Artificial Intelligence · Computer Science 2025-02-25 Sen Yang , Xin Li , Leyang Cui , Lidong Bing , Wai Lam

Clinical communication skills are critical in medical education, and practicing and assessing clinical communication skills on a scale is challenging. Although LLM-powered clinical scenario simulations have shown promise in enhancing…

Artificial Intelligence · Computer Science 2025-06-16 Weibing Zheng , Laurah Turner , Jess Kropczynski , Murat Ozer , Tri Nguyen , Shane Halse

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Human reasoning can be understood as a cooperation between the intuitive, associative "System-1" and the deliberative, logical "System-2". For existing System-1-like methods in visual activity understanding, it is crucial to integrate…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Xiaoqian Wu , Yong-Lu Li , Jianhua Sun , Cewu Lu

Understanding the uncertainty in large language model (LLM) explanations is important for evaluating their faithfulness and reasoning consistency, and thus provides insights into the reliability of LLM's output regarding a question. In this…

Computation and Language · Computer Science 2025-09-16 Longchao Da , Xiaoou Liu , Jiaxin Dai , Lu Cheng , Yaqing Wang , Hua Wei

Large Language Models (LLMs) have become valuable assets in mental health, showing promise in both classification tasks and counseling applications. This paper offers a perspective on using LLMs in mental health applications. It discusses…

Computation and Language · Computer Science 2023-12-19 Shaoxiong Ji , Tianlin Zhang , Kailai Yang , Sophia Ananiadou , Erik Cambria

Large language models (LLMs) offer a promising pre-screening tool, improving early disease detection and providing enhanced healthcare access for underprivileged communities. The early diagnosis of various diseases continues to be a…

Artificial Intelligence · Computer Science 2025-04-10 Umakanta Maharana , Sarthak Verma , Avarna Agarwal , Prakashini Mruthyunjaya , Dwarikanath Mahapatra , Sakir Ahmed , Murari Mandal

Large language models are increasingly integrated into decision-making in areas such as healthcare, law, finance, engineering, and government. Yet they share a critical limitation: they produce fluent outputs even when their internal…

Artificial Intelligence · Computer Science 2026-04-17 Rikard Rosenbacke , Carl Rosenbacke , Victor Rosenbacke , Martin McKee

High-assurance reasoning, particularly in critical domains such as law and medicine, requires conclusions that are accurate, verifiable, and explicitly grounded in evidence. This reasoning relies on premises codified from rules, statutes,…

Artificial Intelligence · Computer Science 2025-10-03 Navapat Nananukul , Yue Zhang , Ryan Lee , Eric Boxer , Jonathan May , Vibhav Giridhar Gogate , Jay Pujara , Mayank Kejriwal

Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may…

Machine Learning · Computer Science 2025-11-21 Dong Chen , Yanzhe Wei , Zonglin He , Guan-Ming Kuang , Canhua Ye , Meiru An , Huili Peng , Yong Hu , Huiren Tao , Kenneth MC Cheung

Pre-trained large language models (LMs) struggle to perform logical reasoning reliably despite advances in scale and compositionality. In this work, we tackle this challenge through the lens of symbolic programming. We propose DSR-LM, a…

Artificial Intelligence · Computer Science 2023-05-09 Hanlin Zhang , Jiani Huang , Ziyang Li , Mayur Naik , Eric Xing

Rule-based reasoning over natural language input arises in domains where decisions must be auditable and justifiable: clinical protocols specify eligibility criteria in prose, evidence rules define admissibility through textual conditions,…

Artificial Intelligence · Computer Science 2026-01-06 Albert Sadowski , Jarosław A. Chudziak

Large Language Models (LLMs) have demonstrated impressive capabilities, yet their deployment in high-stakes domains is hindered by inherent limitations in trustworthiness, including hallucinations, instability, and a lack of transparency.…

Computation and Language · Computer Science 2025-10-21 David Peer , Sebastian Stabinger
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