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Medicine is rife with high-stakes uncertainty. Doctors routinely make clinical judgments and decisions that juggle many fundamental unknowns, like predictions about what might be causing a patients' symptoms or decisions about what…

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

As demand for mental health care outpaces clinician-delivered assessment, scalable screening tools are increasingly needed. Large language models (LLMs) may identify psychiatric risk from patient narratives, but their reliability across…

Computation and Language · Computer Science 2026-05-26 Jianfeng Zhu , Megan Korhummel , Ruoming Jin , Karin G. Coifman

In recent years, large language models (LLMs) have demonstrated significant success in performing varied natural language tasks such as language translation, question-answering, summarizing, fact-checking, etc. Despite LLMs' impressive…

Computation and Language · Computer Science 2025-03-03 Bishwamittra Ghosh , Sarah Hasan , Naheed Anjum Arafat , Arijit Khan

Large language models (LLMs) have achieved remarkable capabilities across diverse tasks, yet their internal decision-making processes remain largely opaque. Mechanistic interpretability (i.e., the systematic study of how neural networks…

Computation and Language · Computer Science 2026-02-13 Usman Naseem

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Human-Computer Interaction · Computer Science 2026-04-23 Gaoussou Youssouf Kebe , Jeffrey M. Girard , Einat Liebenthal , Justin Baker , Fernando De la Torre , Louis-Philippe Morency

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

Artificial Intelligence · Computer Science 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

Recent progress in multimodal large language models (MLLMs) has demonstrated promising performance on medical benchmarks and in preliminary trials as clinical assistants. Yet, our pilot audit of diagnostic cases uncovers a critical failure…

Artificial Intelligence · Computer Science 2025-09-30 Hongjun Liu , Yinghao Zhu , Yuhui Wang , Yitao Long , Zeyu Lai , Lequan Yu , Chen Zhao

Explainable recommender systems are designed to elucidate the explanation behind each recommendation, enabling users to comprehend the underlying logic. Previous works perform rating prediction and explanation generation in a multi-task…

Information Retrieval · Computer Science 2025-04-09 Shijie Liu , Ruixing Ding , Weihai Lu , Jun Wang , Mo Yu , Xiaoming Shi , Wei Zhang

In recent years, Large Language Models (LLMs) have become fundamental to a broad spectrum of artificial intelligence applications. As the use of LLMs expands, precisely estimating the uncertainty in their predictions has become crucial.…

Artificial Intelligence · Computer Science 2024-10-29 Mohammad Beigi , Sijia Wang , Ying Shen , Zihao Lin , Adithya Kulkarni , Jianfeng He , Feng Chen , Ming Jin , Jin-Hee Cho , Dawei Zhou , Chang-Tien Lu , Lifu Huang

Uncertainty decomposition refers to the task of decomposing the total uncertainty of a predictive model into aleatoric (data) uncertainty, resulting from inherent randomness in the data-generating process, and epistemic (model) uncertainty,…

Computation and Language · Computer Science 2024-06-12 Bairu Hou , Yujian Liu , Kaizhi Qian , Jacob Andreas , Shiyu Chang , Yang Zhang

The advancement of Large Language Models (LLMs) has greatly improved our ability to process complex language. However, accurately detecting logical fallacies remains a significant challenge. This study presents a novel and effective prompt…

Artificial Intelligence · Computer Science 2025-04-01 Jiwon Jeong , Hyeju Jang , Hogun Park

Mathematical reasoning and optimization are fundamental to artificial intelligence and computational problem-solving. Recent advancements in Large Language Models (LLMs) have significantly improved AI-driven mathematical reasoning, theorem…

Artificial Intelligence · Computer Science 2025-03-25 Ali Forootani

Automatic differential diagnosis (DDx) is an essential medical task that generates a list of potential diseases as differentials based on patient symptom descriptions. In practice, interpreting these differential diagnoses yields…

Computation and Language · Computer Science 2024-11-08 Shuang Zhou , Mingquan Lin , Sirui Ding , Jiashuo Wang , Genevieve B. Melton , James Zou , Rui Zhang

Existing end-to-end autonomous driving models rely heavily on purely data-driven inductive reasoning. This "black-box" nature leads to a lack of interpretability and absolute safety guarantees in complex, long-tail scenarios. To overcome…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Hongyan Wei , Wael AbdAlmageed

Large language models (LLMs) face the challenge of hallucinations -- outputs that seem coherent but are actually incorrect. A particularly damaging type is fact-conflicting hallucination (FCH), where generated content contradicts…

Computation and Language · Computer Science 2025-02-20 Ningke Li , Yahui Song , Kailong Wang , Yuekang Li , Ling Shi , Yi Liu , Haoyu Wang

As large language models (LLMs) become integrated into everyday and high-stakes decision-making, they inherit the ambiguity and biases of human language. While they produce fluent and coherent outputs, they rely on statistical pattern…

Artificial Intelligence · Computer Science 2026-04-17 Rikard Rosenbacke , Carl Rosenbacke , Victor Rosenbacke , Martin McKee

Recent studies have shown that Large Language Models (LLMs) can achieve strong reasoning performance by incorporating functional symbolic representations that abstractly describe graph traversal algorithms and step-by-step reasoning in…

Artificial Intelligence · Computer Science 2026-05-28 Phuong Minh Nguyen , Tien Huu Dang , Naoya Inoue
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