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Brain foundation models (BFMs) have emerged as a transformative paradigm in computational neuroscience, offering a revolutionary framework for processing diverse neural signals across different brain-related tasks. These models leverage…
Video Foundation Models (ViFMs) aim to learn a general-purpose representation for various video understanding tasks. Leveraging large-scale datasets and powerful models, ViFMs achieve this by capturing robust and generic features from video…
Empirical evaluation serves as the primary compass guiding research progress in foundation models. Despite a large body of work focused on training frontier vision-language models (VLMs), approaches to their evaluation remain nascent. To…
Multi-model routing has evolved from an engineering technique into essential infrastructure, yet existing work lacks a systematic, reproducible benchmark for evaluating vision-language models (VLMs). We present VL-RouterBench to assess the…
The advent of foundation models, particularly Vision-Language Models (VLMs) and Multi-modal Large Language Models (MLLMs), has redefined the frontiers of artificial intelligence, enabling remarkable generalization across diverse tasks with…
The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…
Benchmarking has been the cornerstone of progress in computer vision, natural language processing, and the broader deep learning domain, driving algorithmic innovation through standardized datasets and reproducible evaluation protocols. The…
Background: Large foundation models have revolutionized single-cell analysis, yet no kidney-specific model currently exists, and it remains unclear whether organ-focused models can outperform generalized models. The kidney's complex…
Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…
Safety-critical systems with neural network components require strong guarantees. While existing neural network verification techniques have shown great progress towards this goal, they cannot prove the absence of software faults in the…
Tandem mass spectrometry has played a pivotal role in advancing proteomics, enabling the high-throughput analysis of protein composition in biological tissues. Many deep learning methods have been developed for \emph{de novo} peptide…
Dynamic modelling is one of the cornerstones of systems biology. Many research efforts are currently being invested in the development and exploitation of large-scale kinetic models. The associated problems of parameter estimation (model…
Recent Vision-Language Models (VLMs) have made remarkable progress in multimodal understanding tasks, yet their evaluation on long video understanding remains unreliable. Due to limited frame inputs, key frames necessary for answering the…
Biomedical entity linking (BEL) is the task of grounding entity mentions to a knowledge base. It plays a vital role in information extraction pipelines for the life sciences literature. We review recent work in the field and find that, as…
Foundation models (FMs) are large-scale deep learning models trained on massive datasets, often using self-supervised learning techniques. These models serve as a versatile base for a wide range of downstream tasks, including those in…
Although large visual-language models (LVLMs) have demonstrated strong performance in multimodal tasks, errors may occasionally arise due to biases during the reasoning process. Recently, reward models (RMs) have become increasingly pivotal…
Causal inference is a vital aspect of multiple scientific disciplines and is routinely applied to high-impact applications such as medicine. However, evaluating the performance of causal inference methods in real-world environments is…
Open-weight bio-foundation models present a dual-use dilemma. While holding great promise for accelerating scientific research and drug development, they could also enable bad actors to develop more deadly bioweapons. To mitigate the risk…
The automatic generation of Verilog code using Large Language Models (LLMs) has garnered significant interest in hardware design automation. However, existing benchmarks for evaluating LLMs in Verilog generation fall short in replicating…
The motif-scaffolding problem is a central task in computational protein design: Given the coordinates of atoms in a geometry chosen to confer a desired biochemical function (a motif), the task is to identify diverse protein structures…