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Batch effects arising from technical variations in histopathology staining protocols, scanners, and acquisition pipelines pose a persistent challenge for computational pathology, hindering cross-batch generalization and limiting reliable…

Machine Learning · Computer Science 2026-03-02 Xiaolong Zhang , Jianwei Zhang , Selim Sevim , Emek Demir , Ece Eksi , Xubo Song

While Large Language Models (LLMs) excel in world knowledge understanding, adapting them to specific subfields requires precise adjustments. Due to the model's vast scale, traditional global fine-tuning methods for large models can be…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Jiawei Chen , Yue Jiang , Dingkang Yang , Mingcheng Li , Jinjie Wei , Ziyun Qian , Lihua Zhang

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Artificial Intelligence · Computer Science 2024-12-04 Kai Sun , Siyan Xue , Fuchun Sun , Haoran Sun , Yu Luo , Ling Wang , Siyuan Wang , Na Guo , Lei Liu , Tian Zhao , Xinzhou Wang , Lei Yang , Shuo Jin , Jun Yan , Jiahong Dong

In this work, we propose to tackle the problem of domain generalization in the context of \textit{insufficient samples}. Instead of extracting latent feature embeddings based on deterministic models, we propose to learn a domain-invariant…

Machine Learning · Computer Science 2024-02-12 Kecheng Chen , Elena Gal , Hong Yan , Haoliang Li

Foundation models (FMs) trained on electronic health records (EHRs) have shown strong performance on a range of clinical prediction tasks. However, adapting these models to local health systems remains challenging due to limited data…

The rapid proliferation of open-source medical foundation models (FMs) raises a practical question: how well do their pre-trained representations transfer to clinically relevant but data-scarce classification tasks? Particularly in CT-based…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Hartmut Häntze , Sarah de Boer , Myrthe Buser , Alessa Hering , Bram van Ginneken , Mathias Prokop , Jawed Nawabi , Sebastian Ziegelmayer , Lisa Adams , Keno Bressem

Deep learning-based fault diagnosis (FD) approaches require a large amount of training data, which are difficult to obtain since they are located across different entities. Federated learning (FL) enables multiple clients to collaboratively…

Machine Learning · Computer Science 2023-10-16 Jixuan Cui , Jun Li , Zhen Mei , Kang Wei , Sha Wei , Ming Ding , Wen Chen , Song Guo

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

In recent years, machine learning has made significant progress in clinical outcome prediction, demonstrating increasingly accurate results. However, the substantial resources required for hospitals to train these models, such as data…

Machine Learning · Computer Science 2026-05-06 Ryan King , Conrad Krueger , Ethan Veselka , Tianbao Yang , Bobak J. Mortazavi

Recent work shows that fine-tuned Large Language Models (LLMs) can achieve high valid plan rates on PDDL planning tasks. However, it remains unclear whether this reflects transferable planning competence or domain-specific memorization. In…

Artificial Intelligence · Computer Science 2026-01-22 Valerio Belcamino , Nicholas Attolino , Alessio Capitanelli , Fulvio Mastrogiovanni

Medical vision foundation models remain limited in downstream tasks, particularly volumetric medical image segmentation. While fine-tuning on labeled target-domain data improves performance, existing approaches typically rely on randomly…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Jin Yang , Daniel S. Marcus , Aristeidis Sotiras

Federated learning (FL) enables collaborative model training across decentralized medical institutions while preserving data privacy. However, medical FL benchmarks remain scarce, with existing efforts focusing mainly on unimodal or bimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Aavash Chhetri , Bibek Niroula , Pratik Shrestha , Yash Raj Shrestha , Lesley A Anderson , Prashnna K Gyawali , Loris Bazzani , Binod Bhattarai

Knowledge sharing is crucial in healthcare, especially when leveraging data from multiple clinical sites to address data scarcity, reduce costs, and enable timely interventions. Transfer learning can facilitate cross-site knowledge…

Computation and Language · Computer Science 2024-09-24 Yuhe Gao , Runxue Bao , Yuelyu Ji , Yiming Sun , Chenxi Song , Jeffrey P. Ferraro , Ye Ye

Progress in a research field can be hard to assess, in particular when many concurrent methods are proposed in a short period of time. This is the case in digital pathology, where many foundation models have been released recently to serve…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Pierre Marza , Leo Fillioux , Sofiène Boutaj , Kunal Mahatha , Christian Desrosiers , Pablo Piantanida , Jose Dolz , Stergios Christodoulidis , Maria Vakalopoulou

Fine-tuning large language models (LLMs) using diverse datasets is crucial for enhancing their overall performance across various domains. In practical scenarios, existing methods based on modeling the mixture proportions of data…

Computation and Language · Computer Science 2025-10-31 Zhenqing Ling , Daoyuan Chen , Liuyi Yao , Qianli Shen , Yaliang Li , Ying Shen

Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Learning medical visual representations from image-report pairs through joint learning has garnered increasing research attention due to its potential to alleviate the data scarcity problem in the medical domain. The primary challenges stem…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jun Wang , Lixing Zhu , Xiaohan Yu , Abhir Bhalerao , Yulan He

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

Reducing domain divergence is a key step in transfer learning problems. Existing works focus on the minimization of global domain divergence. However, two domains may consist of several shared subdomains, and differ from each other in each…

Machine Learning · Computer Science 2020-05-08 Pengfei Wei , Yiping Ke , Xinghua Qu , Tze-Yun Leong

Existing pretraining data mixing methods for large language models (LLMs) typically follow a domain-wise methodology, a top-down process that first determines domain weights and then performs uniform data sampling across each domain.…

Computation and Language · Computer Science 2025-03-04 Xiangyu Xi , Deyang Kong , Jian Yang , Jiawei Yang , Zhengyu Chen , Wei Wang , Jingang Wang , Xunliang Cai , Shikun Zhang , Wei Ye
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