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Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

Machine Learning (ML) based prognostics and health monitoring (PHM) tools provide new opportunities for manufacturers to operate and maintain their equipment in a risk-optimized manner and utilize it more sustainably along its lifecycle.…

Machine Learning · Computer Science 2024-05-15 Christoph Netsch , Till Schöpe , Benedikt Schindele , Joyam Jayakumar

Semi-supervised learning is of great significance in medical image segmentation by exploiting unlabeled data. Among its strategies, the co-training framework is prominent. However, previous co-training studies predominantly concentrate on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Pengcheng Zhou , Lantian Zhang , Wei Li

Mitotic figures are classified into typical and atypical variants, with atypical counts correlating strongly with tumor aggressiveness. Accurate differentiation is therefore essential for patient prognostication and resource allocation, yet…

Image and Video Processing · Electrical Eng. & Systems 2025-09-19 Mieko Ochi , Bae Yuan

Multimodal Large Language Models (MLLMs) have made significant advancements, demonstrating powerful capabilities in processing and understanding multimodal data. Fine-tuning MLLMs with Federated Learning (FL) allows for expanding the…

Machine Learning · Computer Science 2025-03-11 Binqian Xu , Xiangbo Shu , Haiyang Mei , Guosen Xie , Basura Fernando , Jinhui Tang

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Pathology foundation models (PFMs) have emerged as powerful tools for analyzing whole slide images (WSIs). However, adapting these pretrained PFMs for specific clinical tasks presents considerable challenges, primarily due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Neeraj Kumar , Swaraj Nanda , Siddharth Singi , Jamal Benhamida , David Kim , Jie-Fu Chen , Amir Momeni-Boroujeni , Gregory M. Goldgof , Gabriele Campanella , Chad Vanderbilt

Adversarial training based on the maximum classifier discrepancy between two classifier structures has achieved great success in unsupervised domain adaptation tasks for image classification. The approach adopts the structure of two…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Yiju Yang , Taejoon Kim , Guanghui Wang

Covariate shifts are a common problem in predictive modeling on real-world problems. This paper proposes addressing the covariate shift problem by minimizing Maximum Mean Discrepancy (MMD) statistics between the training and test sets in…

Machine Learning · Computer Science 2022-03-03 Liwen Ouyang , Aaron Key

Large Language Models (LLMs) are increasingly adopted across domains such as education, healthcare, and finance. In healthcare, LLMs support tasks including disease diagnosis, abnormality classification, and clinical decision-making. Among…

Cryptography and Security · Computer Science 2026-03-31 Payel Bhattacharjee , Fengwei Tian , Geoffrey D. Rubin , Joseph Y. Lo , Nirav Merchant , Heidi Hanson , John Gounley , Ravi Tandon

Large Language Models(LLMs) excel in general tasks but struggle in specialized domains like healthcare due to limited domain-specific knowledge.Supervised Fine-Tuning(SFT) data construction for domain adaptation often relies on heuristic…

Machine Learning · Computer Science 2025-09-19 Hongxin Ding , Yue Fang , Runchuan Zhu , Xinke Jiang , Jinyang Zhang , Yongxin Xu , Xu Chu , Junfeng Zhao , Yasha Wang

In domain adaptation, maximum mean discrepancy (MMD) has been widely adopted as a discrepancy metric between the distributions of source and target domains. However, existing MMD-based domain adaptation methods generally ignore the changes…

Computer Vision and Pattern Recognition · Computer Science 2017-05-02 Hongliang Yan , Yukang Ding , Peihua Li , Qilong Wang , Yong Xu , Wangmeng Zuo

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Existing unsupervised domain adaptation methods based on adversarial learning have achieved good performance in several medical imaging tasks. However, these methods focus only on global distribution adaptation and ignore distribution…

Computer Vision and Pattern Recognition · Computer Science 2022-07-11 Wei Feng , Lin Wang , Lie Ju , Xin Zhao , Xin Wang , Xiaoyu Shi , Zongyuan Ge

Foundation models hold promise for transforming AI in healthcare by providing modular components that are easily adaptable to downstream healthcare tasks, making AI development more scalable and cost-effective. Structured EHR foundation…

Federated Domain Adaptation (FDA) is a Federated Learning (FL) scenario where models are trained across multiple clients with unique data domains but a shared category space, without transmitting private data. The primary challenge in FDA…

Machine Learning · Computer Science 2024-10-11 Jingyuan Zhang , Yiyang Duan , Shuaicheng Niu , Yang Cao , Wei Yang Bryan Lim

Large language models (LLMs) can generate programs that pass unit tests, but passing tests does not guarantee reliable runtime behavior. We find that different correct solutions to the same task can show very different memory and…

Multimodal Large Language Models (MLLMs) have shown strong potential for radiology report generation, yet their clinical translation is hindered by architectural heterogeneity and the prevalence of factual hallucinations. Standard…

Machine Learning · Computer Science 2026-01-13 Kun Zhao , Siyuan Dai , Pan Wang , Jifeng Song , Hui Ji , Chenghua Lin , Liang Zhan , Haoteng Tang

Large Language Models (LLMs) are being applied in a wide array of settings, well beyond the typical language-oriented use cases. In particular, LLMs are increasingly used as a plug-and-play method for fitting data and generating…

Machine Learning · Computer Science 2025-10-29 Hejia Liu , Mochen Yang , Gediminas Adomavicius

Reproducibility remains a critical challenge in foundation model training for histopathology, often hindered by software randomness, hardware non-determinism, and inconsistent hyperparameter reporting. To investigate these issues, we…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Usman Afzaal , Ziyu Su , Usama Sajjad , Hao Lu , Mostafa Rezapour , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi