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Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Pathology foundation models (PFMs) have become central to computational pathology, aiming to offer general encoders for feature extraction from whole-slide images (WSIs). Despite strong benchmark performance, PFM robustness to real-world…

Image and Video Processing · Electrical Eng. & Systems 2026-01-08 Erik Thiringer , Fredrik K. Gustafsson , Kajsa Ledesma Eriksson , Mattias Rantalainen

The advancement of large language models (LLMs) has opened new frontiers in natural language processing, particularly in specialized domains like healthcare. In this paper, we propose the Incremental Curriculum-Based Fine-Tuning (ICFT)…

Computation and Language · Computer Science 2025-02-04 Robert Long , Eric Gonzalez , Harrison Fuller

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

This paper narrows the performance gap between small, specialized models and significantly larger general-purpose models through domain adaptation via continual pre-training and merging. We address the scarcity of specialized non-English…

Computation and Language · Computer Science 2026-04-22 Niclas Doll , Jasper Schulze Buschhoff , Shalaka Satheesh , Hammam Abdelwahab , Héctor Allende-Cid , Katrin Klug

Recent advancements in machine learning (ML), natural language processing (NLP), and foundational models have shown promise for real-life applications in critical, albeit compute-constrainted fields like healthcare. In such areas, combining…

Machine Learning · Computer Science 2025-02-05 Georgios Margaritis , Periklis Petridis , Dimitris J. Bertsimas

We propose a novel approach for domain generalisation (DG) leveraging risk distributions to characterise domains, thereby achieving domain invariance. In our findings, risk distributions effectively highlight differences between training…

Machine Learning · Computer Science 2023-10-31 Toan Nguyen , Kien Do , Bao Duong , Thin Nguyen

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

Federated learning enables multiple hospitals to cooperatively learn a shared model without privacy disclosure. Existing methods often take a common assumption that the data from different hospitals have the same modalities. However, such a…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Yunlu Yan , Hong Wang , Yawen Huang , Nanjun He , Lei Zhu , Yuexiang Li , Yong Xu , Yefeng Zheng

Transformer-based foundation models (FMs) have recently demonstrated remarkable performance in medical image segmentation. However, scaling these models is challenging due to the limited size of medical image datasets within isolated…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yumin Zhang , Yan Gao , Haoran Duan , Hanqing Guo , Tejal Shah , Rajiv Ranjan , Bo Wei

Various deep learning-based systems have been proposed for accurate and convenient plant disease diagnosis, achieving impressive performance. However, recent studies show that these systems often fail to maintain diagnostic accuracy on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Takafumi Nogami , Satoshi Kagiwada , Hitoshi Iyatomi

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

Recent studies show that deep learning models achieve good performance on medical imaging tasks such as diagnosis prediction. Among the models, multimodality has been an emerging trend, integrating different forms of data such as chest…

Machine Learning · Computer Science 2022-02-10 Haodi Zhang , Chenyu Xu , Peirou Liang , Ke Duan , Hao Ren , Weibin Cheng , Kaishun Wu

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

Large Language Model (LLM)-based systems present new opportunities for autonomous health monitoring in sensor-rich industrial environments. This study explores the potential of LLMs to detect and classify faults directly from sensor data,…

Artificial Intelligence · Computer Science 2025-09-30 Xian Yeow Lee , Lasitha Vidyaratne , Ahmed Farahat , Chetan Gupta

Few-shot learning has been studied to adapt models to tasks with very few samples. It holds profound significance, particularly in clinical tasks, due to the high annotation cost of medical images. Several works have explored few-shot…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Kaipeng Zheng , Weiran Huang , Lichao Sun

Protein Language Models (PLMs) have emerged as performant and scalable tools for predicting the functional impact and clinical significance of protein-coding variants, but they still lag experimental accuracy. Here, we present a novel…

The combination of multimodal Vision-Language Models (VLMs) and Large Language Models (LLMs) opens up new possibilities for medical classification. This work offers a rigorous, unified benchmark by using four publicly available datasets…

Artificial Intelligence · Computer Science 2026-01-26 Meet Raval , Tejul Pandit , Dhvani Upadhyay

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

Deploying deep learning-based imaging tools across various clinical sites poses significant challenges due to inherent domain shifts and regulatory hurdles associated with site-specific fine-tuning. For histopathology, stain normalization…