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Revealing novel insights from the relationship between molecular measurements and pathology remains a very impactful application of machine learning in biomedicine. Data in this domain typically contain only a few observations but thousands…

Machine Learning · Computer Science 2026-03-31 Christopher Kolberg , Jules Kreuer , Jonas Huurdeman , Sofiane Ouaari , Katharina Eggensperger , Nico Pfeifer

Cross-layer feature pyramid networks (CFPNs) have achieved notable progress in multi-scale feature fusion and boundary detail preservation for salient object detection. However, traditional CFPNs still suffer from two core limitations: (1)…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Jin Lian , Zhongyu Wan , Ming Gao , JunFeng Chen

Both limited annotation and domain shift are significant challenges frequently encountered in medical image segmentation, leading to derivative scenarios like semi-supervised medical (SSMIS), semi-supervised medical domain generalization…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Wei Li , Pengcheng Zhou , Linye Ma , Wenyi Zhao , Huihua Yang , Yuchen Guo

Aligning large language models (LLMs) to human preferences is challenging in domains where preference data is unavailable. We address the problem of learning reward models for such target domains by leveraging feedback collected from…

Machine Learning · Computer Science 2025-01-03 David Wu , Sanjiban Choudhury

Multi-pulse magnetic resonance imaging (MRI) is widely utilized for clinical practice such as Alzheimer's disease diagnosis. To train a robust model for multi-pulse MRI classification, it requires large and diverse data from various medical…

Machine Learning · Computer Science 2025-10-21 Ludi Li , Junbin Mao , Hanhe Lin , Xu Tian , Fang-Xiang Wu , Jin Liu

Despite recent advancements in federated learning (FL) for medical image diagnosis, addressing data heterogeneity among clients remains a significant challenge for practical implementation. A primary hurdle in FL arises from the non-IID…

Machine Learning · Computer Science 2024-07-09 Pranab Sahoo , Ashutosh Tripathi , Sriparna Saha , Samrat Mondal

Numerous studies have explored image-based automated systems for plant disease diagnosis, demonstrating impressive diagnostic capabilities. However, recent large-scale analyses have revealed a critical limitation: that the diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Shoma Kudo , Satoshi Kagiwada , Hitoshi Iyatomi

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

Domain shift in digital histopathology can occur when different stains or scanners are used, during stain translation, etc. A deep neural network trained on source data may not generalise well to data that has undergone some domain shift.…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Zeeshan Nisar , Jelica Vasiljević , Pierre Gançarski , Thomas Lampert

Federated learning enables collaborative model training across medical institutions without sharing raw data, but its performance is often limited by domain heterogeneity across clients. Existing approaches to address this challenge fall…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Chamani Shiranthika , Parvaneh Saeedi

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Quantification learning deals with the task of estimating the target label distribution under label shift. In this paper, we first present a unifying framework, distribution feature matching (DFM), that recovers as particular instances…

Machine Learning · Statistics 2023-07-04 Bastien Dussap , Gilles Blanchard , Badr-Eddine Chérief-Abdellatif

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Yupeng Zhang , Adam G. Dunn , Usman Naseem , Jinman Kim

Developing robust artificial intelligence (AI) models that generalize well to unseen datasets is challenging and usually requires large and variable datasets, preferably from multiple institutions. In federated learning (FL), a model is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Soroosh Tayebi Arasteh , Christiane Kuhl , Marwin-Jonathan Saehn , Peter Isfort , Daniel Truhn , Sven Nebelung

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

Foundation models (FMs), i.e., models trained on a vast amount of typically unlabeled data, have become popular and available recently for the domain of histopathology. The key idea is to extract semantically rich vectors from any input…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Jonathan Ganz , Jonas Ammeling , Emely Rosbach , Ludwig Lausser , Christof A. Bertram , Katharina Breininger , Marc Aubreville

Federated learning (FL) promises to enable collaborative machine learning across healthcare sites whilst preserving data privacy. Practical deployment remains limited by statistical heterogeneity arising from differences in patient…

With increasing concerns and regulations on data privacy, fine-tuning pretrained language models (PLMs) in federated learning (FL) has become a common paradigm for NLP tasks. Despite being extensively studied, the existing methods for this…

Computation and Language · Computer Science 2024-09-04 Qianyi Zhao , Chen Qu , Cen Chen , Mingyuan Fan , Yanhao Wang

Accurate disease classification from radiology reports is essential for many applications. While supervised fine-tuning (SFT) of lightweight LLMs improves accuracy, it can degrade reasoning. We propose a two-stage approach: SFT on disease…

Artificial Intelligence · Computer Science 2026-04-22 Yishu Wei , Yi Lin , Adam Flanders , George Shih , Yifan Peng

Although achieving remarkable progress, it is very difficult to induce a supervised classifier without any labeled data. Unsupervised domain adaptation is able to overcome this challenge by transferring knowledge from a labeled source…

Machine Learning · Computer Science 2021-06-29 Yuntao Du , Ruiting Zhang , Xiaowen Zhang , Yirong Yao , Hengyang Lu , Chongjun Wang