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Ultrathin membranes have drawn much attention due to their unprecedented spatial resolution for DNA nanopore sequencing. However, the high translocation velocity (3000-50000 nt/ms) of DNA molecules moving across such membranes limits their…

Soft Condensed Matter · Physics 2016-01-20 Jiandong Feng , Ke Liu , Roman D. Bulushev , Sergey Khlybov , Dumitru Dumcenco , Andras Kis , Aleksandra Radenovic

Optical artificial neural networks (ONNs), analog computing hardware tailored for machine learning, have significant potential for ultra-high computing speed and energy efficiency. We propose a new approach to architectures for ONNs based…

Nanopore membranes are a versatile platform for a wide range of applications ranging from medical sensing to filtration and clean energy generation. To attain high-flux rectifying ionic flow, it is required to produce short channels…

Mesoscale and Nanoscale Physics · Physics 2023-05-12 Alexander Kiy , Shankar Dutt , Christian Notthoff , Maria E. Toimil-Molares , Nigel Kirby , Patrick Kluth

Superconducting nanowire single-photon detectors (SNSPDs) have attracted remarkable interest for visible and near infrared single-photon detection, owing to their outstanding performance. Conventional SNSPDs are generally used as binary…

Applied Physics · Physics 2020-05-21 X. Q. Sun , W. J. Zhang , C. J. Zhang , L. X. You , G. Z. Xu , J. Huang , H. Li , Z. Wang , X. M. Xie

Hierarchical polymer structures such as pNIPAM microgels have been extensively studied for their ability to undergo significant structural and physical transformations that can be controlled by external stimuli such as temperature, pH or…

Soft Condensed Matter · Physics 2017-08-25 Gaurasundar Marc Conley , Söfi Nojd , Marco Braibanti , Peter Schurtenberger , Frank Scheffold

We experimentally demonstrate precision addressing of single quantum emitters by combined optical microscopy and spin resonance techniques. To this end we utilize nitrogen-vacancy (NV) color centers in diamond confined within a few ten…

Quantum Physics · Physics 2017-10-20 Matthias Pfender , Nabeel Aslam , Gerald Waldherr , Jörg Wrachtrup

Superconducting nanowire single-photon detectors (SNSPDs) with high timing resolution and low background counts in the mid infrared (MIR) have the potential to open up numerous opportunities in fields such as exoplanet searches, direct dark…

Scanning electron microscopy (SEM) is the premier method for characterizing the nanoscale surface pores in ultrafiltration (UF) membranes and the support layers of reverse osmosis (RO) membranes. Based on SEM, the conventional understanding…

Surface-enhanced Raman scattering (SERS) provides critical insights into analyte structure, dynamic processes, and intermolecular interactions at the single-molecule level. By exploiting the hotspot formation in the vicinity of plasmonic…

A novel finite-element method for calculating the illumination-dependence of absorption in three-dimensional nanostructures is presented based on the RF module of the COMSOL software package. This method is capable of numerically…

Optics · Physics 2015-05-28 Mária Csete , Áron Sipos , Faraz Najafi , Xiaolong Hu , Karl K. Berggren

Solid-state nanopores offer a powerful platform for nanoscale analysis of individual analytes, including biomolecules and functionalized nanoparticles, by confining them within a precisely defined sensing region. However, their inherently…

We demonstrate that a simple, unscanned polarization-sensitive optical coherence tomography needle probe can be used to perform layer identification in biological tissues. Broadband light from a laser centered at 1310 nm was sent through a…

Medical Physics · Physics 2023-10-06 Danielle J. Harper , Yongjoo Kim , Alejandra Gómez-Ramírez , Benjamin J. Vakoc

Nanopore sensing is a versatile technique for the analysis of molecules on the single-molecule level. However, extracting information from data with established algorithms usually requires time-consuming checks by an experienced researcher…

Quantitative Methods · Quantitative Biology 2018-06-14 Karolis Misiunas , Niklas Ermann , Ulrich F. Keyser

Polymer translocation is a promising strategy for the next-generation DNA sequencing technologies. The use of biological and synthetic nano-pores, however, still suffers from serious drawbacks. In particular, the width of the membrane layer…

Soft Condensed Matter · Physics 2017-11-30 Timothee Menais , Stefano Mossa , Arnaud Buhot

Nanopore sequencing technology remains highly error-prone, making efficient error correction essential in DNA-based data storage. Prior work addressed high error rates using convolutional codes with their decoder coupled with the…

Information Theory · Computer Science 2026-04-02 Anisha Banerjee , Roman Sokolovskii , Thomas Heinis , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

Nanopore sequencing is a widely-used high-throughput genome sequencing technology that can sequence long fragments of a genome into raw electrical signals at low cost. Nanopore sequencing requires two computationally-costly processing steps…

Translocation of DNA through a nanopore with embedded electrodes is at the centre of new rapid inexpensive sequencing methods which allow distinguishing the four nucleobases by their different electronic structure. However, the subnanometer…

Mesoscale and Nanoscale Physics · Physics 2012-06-20 Yuhui He , Makusu Tsutsui , Ralph H. Scheicher , Masateru Taniguchi , Tomoji Kawai

We use dynamic nuclear polarization (DNP) enhanced nuclear magnetic resonance (NMR) at liquid helium temperatures to directly detect hydrogen attached to the surface of silicon microparticles. The proton NMR spectrum from a dry sample of…

Materials Science · Physics 2017-06-08 Mallory L. Guy , Kipp J. van Schooten , Lihuang Zhu , Chandrasekhar Ramanathan

We describe a micromachining process to allow the coupling of an array of single-mode telecommunication fibers to individual superconducting nanowire single photon detectors (SNSPDs). As proof of principle, we show the integration of four…

Instrumentation and Detectors · Physics 2016-12-21 Risheng Cheng , Xiang Guo , Xiaosong Ma , Linran Fan , King Y. Fong , Menno Poot , Hong X. Tang

Conventional focusing methods for Synthetic Aperture Radar (SAR) employ block processing efficiently but remain latency-heavy processes that prevent the realisation of a closed-loop cognitive SAR vision system. We present the first Online…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebastian Fieldhouse , Roberto Del Prete , Gabriele Daga , Nathaniel Rensly , Gabriele Meoni , Kea-Tiong Tang