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This paper tackles automated categorization of Age-related Macular Degeneration (AMD), a common macular disease among people over 50. Previous research efforts mainly focus on AMD categorization with a single-modal input, let it be a color…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Weisen Wang , Xirong Li , Zhiyan Xu , Weihong Yu , Jianchun Zhao , Dayong Ding , Youxin Chen

The concept of biological age (BA), although important in clinical practice, is hard to grasp mainly due to the lack of a clearly defined reference standard. For specific applications, especially in pediatrics, medical image data are used…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Shashank Salian , Thomas Küstner , Daniel Weiskopf , Tobias Hepp , Sergios Gatidis , Bin Yang

In recent years, there are various methods of estimating Biological Age (BA) have been developed. Especially with the development of machine learning (ML), there are more and more types of BA predictions, and the accuracy has been greatly…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Zhaonian Zhang , Richard Jiang , Danny Crookes , Paul Chazot

The point of care services and medication have become simpler with efficient consumer electronics devices in a smart healthcare system. Cardiovascular disease is a critical illness which causes heart failure, and early and prompt…

Computers and Society · Computer Science 2022-12-16 Nidhi Sinha , Teena Jangid , Amit M. Joshi , Saraju P. Mohanty

Vascular age is traditionally measured using invasive methods or through 12-lead electrocardiogram (ECG). This paper utilizes a low-cost single-lead (lead-I) ECG module to predict the vascular age of an apparently healthy young person. In…

Signal Processing · Electrical Eng. & Systems 2024-11-27 S. Anas Ali , M. Saqib Niaz , Mubashir Rehman , Ahsan Mehmood , M. Mahboob Ur Rahman , Kashif Riaz , Qammer H. Abbasi

The Convolutional Neural Network has amazed us with its usage on several applications. Age range estimation using CNN is emerging due to its application in myriad of areas which makes it a state-of-the-art area for research and improve the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Dipesh Gyawali , Prashanga Pokharel , Ashutosh Chauhan , Subodh Chandra Shakya

We describe a novel neural network architecture for the prediction of ventricular tachyarrhythmias. The model receives input features that capture the change in RR intervals and ectopic beats, along with features based on heart rate…

Machine Learning · Computer Science 2018-12-03 Marek Rei , Joshua Oppenheimer , Marek Sirendi

We study the middle cerebral artery blood flow velocity (MCAfv) in humans using transcranial Doppler ultrasonography (TCD). The time series of the axial flow velocity averaged over a cardiac beat interval is found to exhibit clear…

Biological Physics · Physics 2007-05-23 Miroslaw Latka , Marta Glaubic-Latka , Dariusz Latka , Bruce J. West

We present the findings of "The Alzheimer's Disease Prediction Of Longitudinal Evolution" (TADPOLE) Challenge, which compared the performance of 92 algorithms from 33 international teams at predicting the future trajectory of 219…

Populations and Evolution · Quantitative Biology 2021-12-30 Razvan V. Marinescu , Neil P. Oxtoby , Alexandra L. Young , Esther E. Bron , Arthur W. Toga , Michael W. Weiner , Frederik Barkhof , Nick C. Fox , Arman Eshaghi , Tina Toni , Marcin Salaterski , Veronika Lunina , Manon Ansart , Stanley Durrleman , Pascal Lu , Samuel Iddi , Dan Li , Wesley K. Thompson , Michael C. Donohue , Aviv Nahon , Yarden Levy , Dan Halbersberg , Mariya Cohen , Huiling Liao , Tengfei Li , Kaixian Yu , Hongtu Zhu , Jose G. Tamez-Pena , Aya Ismail , Timothy Wood , Hector Corrada Bravo , Minh Nguyen , Nanbo Sun , Jiashi Feng , B. T. Thomas Yeo , Gang Chen , Ke Qi , Shiyang Chen , Deqiang Qiu , Ionut Buciuman , Alex Kelner , Raluca Pop , Denisa Rimocea , Mostafa M. Ghazi , Mads Nielsen , Sebastien Ourselin , Lauge Sorensen , Vikram Venkatraghavan , Keli Liu , Christina Rabe , Paul Manser , Steven M. Hill , James Howlett , Zhiyue Huang , Steven Kiddle , Sach Mukherjee , Anais Rouanet , Bernd Taschler , Brian D. M. Tom , Simon R. White , Noel Faux , Suman Sedai , Javier de Velasco Oriol , Edgar E. V. Clemente , Karol Estrada , Leon Aksman , Andre Altmann , Cynthia M. Stonnington , Yalin Wang , Jianfeng Wu , Vivek Devadas , Clementine Fourrier , Lars Lau Raket , Aristeidis Sotiras , Guray Erus , Jimit Doshi , Christos Davatzikos , Jacob Vogel , Andrew Doyle , Angela Tam , Alex Diaz-Papkovich , Emmanuel Jammeh , Igor Koval , Paul Moore , Terry J. Lyons , John Gallacher , Jussi Tohka , Robert Ciszek , Bruno Jedynak , Kruti Pandya , Murat Bilgel , William Engels , Joseph Cole , Polina Golland , Stefan Klein , Daniel C. Alexander

The brain-age gap is one of the most investigated risk markers for brain changes across disorders. While the field is progressing towards large-scale models, recently incorporating uncertainty estimates, no model to date provides the…

As global population aging intensifies, there is growing interest in the study of biological age. Bones have long been used to evaluate biological age, and the decline in bone density with age is a well-recognized phenomenon in adults.…

The accurate quantification of brain age from MRI has emerged as an important biomarker of brain health. However, existing approaches are often restricted to narrow age ranges and single-modality MRI data, limiting their capacity to capture…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Dingyi Zhang , Ruiying Liu , Yun Wang

Generating realistic MRIs to accurately predict future changes in the structure of brain is an invaluable tool for clinicians in assessing clinical outcomes and analysing the disease progression at the patient level. However, current…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mattia Litrico , Francesco Guarnera , Mario Valerio Giuffrida , Daniele Ravì , Sebastiano Battiato

Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Dmitrii Lachinov , Arunava Chakravarty , Christoph Grechenig , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Several brain disorders can be detected by observing alterations in the brain's structural and functional connectivities. Neurological findings suggest that early diagnosis of brain disorders, such as mild cognitive impairment (MCI), can…

Neurons and Cognition · Quantitative Biology 2021-10-22 Alpay Tekin , Ahmed Nebli , Islem Rekik

Individuals age differently depending on a multitude of different factors such as lifestyle, medical history and genetics. Often, the global chronological age is not indicative of the true ageing process. An organ-based age estimation would…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Karim Armanious , Sherif Abdulatif , Anish Rao Bhaktharaguttu , Thomas Küstner , Tobias Hepp , Sergios Gatidis , Bin Yang

Chronic diseases, such as cardiovascular disease, diabetes, chronic kidney disease, and thyroid disorders, are the leading causes of premature mortality worldwide. Early detection and intervention are crucial for improving patient outcomes,…

Machine Learning · Computer Science 2025-11-04 Houda Belhad , Asmae Bourbia , Salma Boughanja

We propose an interpretable 3D Grid-Attention deep neural network that can accurately predict a person's age and whether they have Alzheimer's disease (AD) from a structural brain MRI scan. Building on a 3D convolutional neural network, we…

Tissues and Organs · Quantitative Biology 2020-11-19 Pradeep Lam , Alyssa H. Zhu , Iyad Ba Gari , Neda Jahanshad , Paul M. Thompson

The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…

Machine Learning · Computer Science 2024-05-28 Dayana K , S. Nandini , Sanjjushri Varshini R

The Circle of Willis (CoW), vital for ensuring consistent blood flow to the brain, is closely linked to ischemic stroke. Accurate assessment of the CoW is important for identifying individuals at risk and guiding appropriate clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-12-04 Wenxuan Zhang , Shuai Li , Xinyi Wang , Yu Sun , Hongyu Kang , Pui Yuk Chryste Wan , Jing Qin , Yuanpeng Zhang , Yong-Ping Zheng , Sai-Kit Lam