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Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Determining if the brain is developing normally is a key component of pediatric neuroradiology and neurology. Brain magnetic resonance imaging (MRI) of infants demonstrates a specific pattern of development beyond simply myelination. While…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Mahdieh Shabanian , Markus Wenzel , John P. DeVincenzo

Human brain development is rapid during infancy and early childhood. Many disease processes impair this development. Therefore, brain developmental age estimation (BDAE) is essential for all diseases affecting cognitive development. Brain…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Mahdieh Shabanian , Eugene C. Eckstein , Hao Chen , John P. DeVincenzo

Purpose- Coarctation of the Aorta (CoA) patient-specific computational fluid dynamics (CFD) studies in resource constrained settings are limited by the available imaging modalities for geometry and velocity data acquisition. Doppler…

Computational Engineering, Finance, and Science · Computer Science 2025-06-04 Vincent Milimo Masilokwa Punabantu , Malebogo Ngoepe , Amit Kumar Mishra , Thomas Aldersley , John Lawrenson , Liesl Zuhlke

Age prediction using brain imaging, such as MRIs, has achieved promising results, with several studies identifying the model's residual as a potential biomarker for chronic disease states. In this study, we developed a brain age predictive…

Machine Learning · Computer Science 2025-04-22 Shahrzad Jamshidi , Arthur Bousquet , Sugata Banerji , Mark F. Conneely , Bita Aslrousta

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi

Deep learning models have achieved state-of-the-art results in estimating brain age, which is an important brain health biomarker, from magnetic resonance (MR) images. However, most of these models only provide a global age prediction, and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-25 Neha Gianchandani , Mahsa Dibaji , Mariana Bento , Ethan MacDonald , Roberto Souza

The cornerstone of stroke care is expedient management that varies depending on the time since stroke onset. Consequently, clinical decision making is centered on accurate knowledge of timing and often requires a radiologist to interpret…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Adam Marcus , Paul Bentley , Daniel Rueckert

Important applications of advancements in machine learning, are in the area of healthcare, more so for neurological disorder detection. A crucial step towards understanding the neurological status, is to estimate the brain age using…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Vamshi Krishna Kancharla , Neelam Sinha

Cerebral small vessel disease (CSVD) is a major vascular contributor to cognitive impairment in ageing, including dementias. Imaging remains the most promising method for in vivo studies of CSVD. To replace the subjective and laborious…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Jiyang Jiang , Dadong Wang , Yang Song , Perminder S. Sachdev , Wei Wen

Dynamic and precise measurement of cerebral blood flow velocity is crucial in neuroscience and the diagnosis of cerebrovascular diseases. Traditional color Doppler ultrasound can only measure the velocity component along the ultrasound…

Medical Physics · Physics 2025-04-25 Shaoyuan Yan , Yiming Ding , Guoao Ma , Yapeng Fu , Kailiang Xu , Dean Ta

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…

Machine Learning · Computer Science 2025-01-06 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

The ability to determine if the brain is developing normally is a key component of pediatric neuroradiology and neurology. Brain magnetic resonance imaging (MRI) of infants demonstrates a specific pattern of development beyond simply…

Image and Video Processing · Electrical Eng. & Systems 2020-10-09 M. Shabanian , A. Siddiqui , H. Chen , J. P. DeVincenzo

Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato

Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated to the accelerated brain aging and brain…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 M. Tanveer , M. A. Ganaie , Iman Beheshti , Tripti Goel , Nehal Ahmad , Kuan-Ting Lai , Kaizhu Huang , Yu-Dong Zhang , Javier Del Ser , Chin-Teng Lin

In this work, deep learning techniques for brain age prediction from magnetic resonance images are investigated, aiming to assist in the identification of biomarkers of the natural aging process. The identification of biomarkers is useful…

Image and Video Processing · Electrical Eng. & Systems 2021-12-24 Victor H. R. Oliveira , Augusto Antunes , Alexandre S. Soares , Arthur D. Reys , Robson Z. Júnior , Saulo D. S. Pedro , Danilo Silva

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

Longitudinal brain analysis is essential for understanding healthy aging and identifying pathological deviations. Longitudinal registration of sequential brain MRI underpins such analyses. However, existing methods are limited by reliance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Bailiang Jian , Jiazhen Pan , Yitong Li , Fabian Bongratz , Ruochen Li , Daniel Rueckert , Benedikt Wiestler , Christian Wachinger

PD is linked to faster brain aging. Sex is recognized as an important factor in PD, such that males are twice as likely as females to have the disease and have more severe symptoms and a faster progression rate. Despite previous research,…

Neurons and Cognition · Quantitative Biology 2023-09-20 Iman Beheshti , Samuel Booth , Ji Hyun Ko

Age prediction from medical images or other health-related non-imaging data is an important approach to data-driven aging research, providing knowledge of how much information a specific tissue or organ carries about the chronological age…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Johan Öfverstedt , Elin Lundström , Håkan Ahlström , Joel Kullberg