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Early detection of chronic kidney disease (CKD) is essential for preventing progression to end-stage renal disease. However, existing screening tools - primarily developed using populations from high-income countries - often underperform in…

Background: Radiation pneumonitis is a side effect of thoracic radiation therapy. Recently, machine learning models with radiomic features have improved radiation pneumonitis prediction by capturing spatial information. To further support…

Machine Learning · Computer Science 2025-05-22 Chanon Puttanawarut , Romen Samuel Wabina , Nat Sirirutbunkajorn

Diabetes is a prevalent chronic condition that compromises the health of millions of people worldwide. Minimally invasive methods are needed to prevent and control diabetes but most devices for measuring glucose levels are invasive and not…

The growing threat of antibiotic resistance necessitates accurate differentiation between bacterial and viral infections for proper antibiotic administration. In this study, a Virus vs. Bacteria machine learning model was developed to…

Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

AI-powered stethoscopes offer a promising alternative for screening rheumatic heart disease (RHD), particularly in regions with limited diagnostic infrastructure. Early detection is vital, yet echocardiography, the gold standard tool,…

Chronic diseases are long-term, manageable, yet typically incurable conditions, highlighting the need for effective preventive strategies. Machine learning has been widely used to assess individual risk for chronic diseases. However, many…

Machine Learning · Computer Science 2025-06-24 Minh Le , Khoi Ton

Risk stratification is a key tool in clinical decision-making, yet current approaches often fail to translate sophisticated survival analysis into actionable clinical criteria. We present a novel method for unsupervised machine learning…

Background and aim: This study aimed to predict methylation status of the O-6 methyl guanine-DNA methyl transferase (MGMT) gene promoter status by using MRI radiomics features, as well as univariate and multivariate analysis. Material and…

With the growing imbalance between limited medical resources and escalating demands, AI-based clinical tasks have become paramount. As a sub-domain, medication recommendation aims to amalgamate longitudinal patient history with medical…

Artificial Intelligence · Computer Science 2023-11-28 Xiang Li , Shunpan Liang , Yulei Hou , Tengfei Ma

Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

Whole genome sequencing (WGS) is quickly becoming the customary means for identification of antimicrobial resistance (AMR) due to its ability to obtain high resolution information about the genes and mechanisms that are causing resistance…

Genomics · Quantitative Biology 2021-07-27 Mattia Prosperi , Simone Marini , Christina Boucher , Jiang Bian

This research presents preliminary work to address the challenge of identifying at-risk students using supervised machine learning and three unique data categories: engagement, demographics, and performance data collected from Fall 2023…

Machine Learning · Computer Science 2025-07-16 Azucena L. Jimenez Martinez , Kanika Sood , Rakeshkumar Mahto

Background: Pregnancy-associated thrombotic microangiopathy (P-TMA) is rare but life-threatening. Early risk prediction before overt clinical presentation remains challenging, as the associated laboratory abnormalities are subtle,…

Machine Learning · Computer Science 2026-05-14 Chuanchuan Sun , Zhen Yu , Qin Fan , Qingchao Chen , Feng Yu

Clinical language models (LMs) are increasingly applied to support clinical risk prediction from free-text notes, yet their uncertainty estimates often remain poorly calibrated and clinically unreliable. In this work, we propose Clinical…

Computation and Language · Computer Science 2026-04-27 Sizhe Wang , Ziqi Xu , Claire Najjuuko , Charles Alba , Chenyang Lu

The canine lymphoma blood test detects the levels of two biomarkers, the acute phase proteins (C-Reactive Protein and Haptoglobin). This test can be used for diagnostics, for screening, and for remission monitoring as well. We analyze…

Quantitative Methods · Quantitative Biology 2014-10-13 E. M. Mirkes , I. Alexandrakis , K. Slater , R. Tuli , A. N. Gorban

Clinical randomized controlled trials (RCTs) collect hundreds of measurements spanning various metric types (e.g., laboratory tests, cognitive/motor assessments, etc.) across 100s-1000s of subjects to evaluate the effect of a treatment, but…

Machine Learning · Computer Science 2024-06-25 Sayeri Lala , Niraj K. Jha

Pathological complete response (pCR) is a key prognostic factor in breast cancer patients undergoing neoadjuvant therapy, strongly associated with long-term survival and treatment personalization. However, accurate pre-treatment pCR…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Alice Natalina Caragliano , Valerio Guarrasi , Michela Gravina , Carlo Sansone , Paolo Soda

Purpose: To develop high throughput multi-label annotators for body (chest, abdomen, and pelvis) Computed Tomography (CT) reports that can be applied across a variety of abnormalities, organs, and disease states. Approach: We used a…

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