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The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Early detection of clinical outcomes such as cancer may be predicted based on longitudinal biomarker measurements. Tracking longitudinal biomarkers as a way to identify early disease onset may help to reduce mortality from diseases like…

Automated malaria diagnosis is a difficult but high-value target for machine learning (ML), and effective algorithms could save many thousands of children's lives. However, current ML efforts largely neglect crucial use case constraints and…

Machine Learning · Computer Science 2023-07-06 Charles B. Delahunt , Noni Gachuhi , Matthew P. Horning

In recent years, ML algorithms have been shown to be useful for predicting diseases based on health data and posed a potential application area for these algorithms such as modeling of diseases. The majority of these applications employ…

Machine Learning · Computer Science 2024-12-24 Elham Musaaed , Nabil Hewahi , Abdulla Alasaadi

Multiple myeloma (MM) is preceded by a long preclinical phase spanning decades, yet scalable, non-specialist tools to identify individuals at elevated risk before end-organ damage are lacking. In a prospective analysis of 299,035…

Applications · Statistics 2026-04-07 Bingjie Li , Jiadai Xu , Yiqing Sun , Feiyue Pan , Shing-Tung Yau , Peng Liu , Zhigang Yao

Purpose: To examine whether incorporating anatomical awareness into a deep learning model can improve generalizability and enable prediction of disease progression. Methods: This retrospective multicenter study included conventional pelvic…

Background: While machine learning (ML) models are rapidly emerging as promising screening tools in critical care medicine, the identification of homogeneous subphenotypes within populations with heterogeneous conditions such as pediatric…

Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…

Machine Learning · Computer Science 2025-10-13 Tianyi Chen , Mingcheng Zhu , Zhiyao Luo , Tingting Zhu

Raman spectroscopy's capability to provide meaningful composition predictions is heavily reliant on a pre-processing step to remove insignificant spectral variation. This is crucial in biofluid analysis. Widespread adoption of diagnostics…

Signal Processing · Electrical Eng. & Systems 2019-04-05 Emily E Storey , Amr S. Helmy

Cystic hygroma is a high-risk prenatal ultrasound finding that portends high rates of chromosomal abnormalities, structural malformations, and adverse pregnancy outcomes. Automated detection can increase reproducibility and support scalable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Youssef Megahed , Robin Ducharme , Inok Lee , Inbal Willner , Adrian D. C. Chan , Mark Walker , Steven Hawken

Aim: In the present work, we aimed to evaluate a comprehensive radiomics framework that enabled prediction of EGFR and KRAS mutation status in NSCLC cancer patients based on PET and CT multi-modalities radiomic features and machine learning…

The worldwide increase of antimicrobial resistance (AMR) is a serious threat to human health. To avert the spread of AMR, fast reliable diagnostics tools that facilitate optimal antibiotic stewardship are an unmet need. In this regard,…

Background: Deep learning has presented great potential in accurate MR image segmentation when enough labeled data are provided for network optimization. However, manually annotating 3D MR images is tedious and time-consuming, requiring…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Yousuf Babiker M. Osman , Cheng Li , Weijian Huang , Shanshan Wang

Areas where Artificial Intelligence (AI) & related fields are finding their applications are increasing day by day, moving from core areas of computer science they are finding their applications in various other domains.In recent times…

Machine Learning · Computer Science 2016-07-19 Sahil Sharma , Vinod Sharma , Atul Sharma

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Objective: Post-traumatic epilepsy (PTE) is a debilitating neurological disorder that develops after traumatic brain injury (TBI). Early prediction of PTE remains challenging due to heterogeneous clinical data, limited positive cases, and…

Machine Learning · Computer Science 2026-04-17 Wenhui Cui , Nicholas Swingle , Anand A. Joshi , Dileep Nair , Richard M. Leahy

Prostate cancer diagnosis through MR imaging have currently relied on radiologists' interpretation, whilst modern AI-based methods have been developed to detect clinically significant cancers independent of radiologists. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Xiangcen Wu , Yipei Wang , Qianye Yang , Natasha Thorley , Shonit Punwani , Veeru Kasivisvanathan , Ester Bonmati , Yipeng Hu

Aimed to develop and validate a CT radiomics-based explainable machine learning model for precise diagnosing malignancy and benignity specifically in endometrial cancer (EC) patients. A total of 83 EC patients from two centers, including 46…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Tingrui Zhang , Honglin Wu , Zekun Jiang , Yingying Wang , Rui Ye , Huiming Ni , Chang Liu , Jin Cao , Xuan Sun , Rong Shao , Xiaorong Wei , Yingchun Sun

The developing field of enhanced diagnostic techniques in the diagnosis of infectious diseases, constitutes a crucial domain in modern healthcare. By utilizing Gas Chromatography-Ion Mobility Spectrometry (GC-IMS) data and incorporating…

Precise prognostic stratification of colorectal cancer (CRC) remains a major clinical challenge due to its high heterogeneity. The conventional TNM staging system is inadequate for personalized medicine. We aimed to develop and validate a…

Machine Learning · Computer Science 2025-11-20 Zisong Wang , Xuanyu Wang , Hang Chen , Haizhou Wang , Yuxin Chen , Yihang Xu , Yunhe Yuan , Lihuan Luo , Xitong Ling , Xiaoping Liu