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Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Information Retrieval · Computer Science 2026-04-14 Avi-ad Avraam Buskila

Recently, both closed-source LLMs and open-source communities have made significant strides, outperforming humans in various general domains. However, their performance in specific professional domains such as medicine, especially within…

Computation and Language · Computer Science 2024-12-24 Lulu Zhao , Weihao Zeng , Xiaofeng Shi , Hua Zhou

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

Computational Fluid Dynamics (CFD) is widely used in aerospace, energy, and biology to model fluid flow, heat transfer, and chemical reactions. While Large Language Models (LLMs) have transformed various domains, their application in CFD…

Artificial Intelligence · Computer Science 2025-02-04 Yuxuan Chen , Xu Zhu , Hua Zhou , Zhuyin Ren

Large Language Models (LLMs) have made great strides in recent years to achieve unprecedented performance across different tasks. However, due to commercial interest, the most competitive models like GPT, Gemini, and Claude have been gated…

Recent advances in large language models have enabled their application to a range of healthcare tasks. However, aligning LLMs with the nuanced demands of medical ethics, especially under complex real world scenarios, remains underexplored.…

Computation and Language · Computer Science 2026-01-14 Haoan Jin , Han Ying , Jiacheng Ji , Hanhui Xu , Mengyue Wu

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, and AI systems can expand access to fundus photography screening. Current FDA-cleared systems primarily provide binary referral outputs, where this minimal output may…

Artificial Intelligence · Computer Science 2025-09-17 Nadim Barakat , William Lotter

Background: Clinical guidelines are central to safe evidence-based medicine in modern healthcare, providing diagnostic criteria, treatment options and monitoring advice for a wide range of illnesses. LLM-empowered chatbots have shown great…

Computation and Language · Computer Science 2025-05-07 Julia Ive , Felix Jozsa , Nick Jackson , Paulina Bondaronek , Ciaran Scott Hill , Richard Dobson

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

Accurate symptom-to-disease classification and clinically grounded treatment recommendations remain challenging, particularly in heterogeneous patient settings with high diagnostic risk. Existing large language model (LLM)-based systems…

Matching cancer patients to clinical trials is essential for advancing treatment and patient care. However, the inconsistent format of medical free text documents and complex trial eligibility criteria make this process extremely…

Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without sophisticated tools. We developed COMO, a user-friendly…

This work presents a custom approach to developing a domain specific knowledge assistant for sustainability reporting using the International Financial Reporting Standards (IFRS). In this domain, there is no publicly available…

Computation and Language · Computer Science 2025-02-07 Maria-Flavia Lovin

Recent multimodal large language models (MLLMs) have shown strong chain-of-thought (CoT) reasoning ability on vision-language tasks, but their direct deployment in real-world systems is often limited by latency and resource constraints. In…

Computation and Language · Computer Science 2026-05-13 Yuanhao Yue , Chengyu Wang , Yuanjie Lyu , Lei Shen , Jun Huang

Accurate diagnosis of ocular surface diseases is critical in optometry and ophthalmology, which hinge on integrating clinical data sources (e.g., meibography imaging and clinical metadata). Traditional human assessments lack precision in…

Computation and Language · Computer Science 2024-10-02 Chun-Hsiao Yeh , Jiayun Wang , Andrew D. Graham , Andrea J. Liu , Bo Tan , Yubei Chen , Yi Ma , Meng C. Lin

Despite the growing adoption of electronic health records, many processes still rely on paper documents, reflecting the heterogeneous real-world conditions in which healthcare is delivered. The manual transcription process is time-consuming…

Evaluating large language models (LLMs) for medical applications remains challenging due to benchmark saturation, limited data accessibility, and insufficient coverage of relevant tasks. Existing suites have either saturated, heavily depend…

In real-world machine learning (ML) pipelines, datasets are continuously growing. Models must incorporate this new training data to improve generalization and adapt to potential distribution shifts. The cost of model retraining is…

Machine Learning · Computer Science 2025-01-27 Maximilian Böther , Ties Robroek , Viktor Gsteiger , Robin Holzinger , Xianzhe Ma , Pınar Tözün , Ana Klimovic

Current LLMs for creating fully-structured reports face the challenges of formatting errors, content hallucinations, and privacy leakage issues when uploading data to external servers.We aim to develop an open-source, accurate LLM for…

Artificial Intelligence · Computer Science 2025-09-29 Chuang Niu , Md Sayed Tanveer , Md Zabirul Islam , Parisa Kaviani , Qing Lyu , Mannudeep K. Kalra , Christopher T. Whitlow , Ge Wang

Vision-language foundation models (VLMs) show promise for diverse imaging tasks but often underperform on medical benchmarks. Prior efforts to improve performance include model finetuning, which requires large domain-specific datasets and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Arnav Singhvi , Vasiliki Bikia , Asad Aali , Akshay Chaudhari , Roxana Daneshjou