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While Retrieval-Augmented Generation (RAG) has exhibited promise in utilizing external knowledge, its generation process heavily depends on the quality and accuracy of the retrieved context. Large language models (LLMs) struggle to evaluate…

Computation and Language · Computer Science 2025-10-13 Shi-Qi Yan , Quan Liu , Zhen-Hua Ling

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Machine learning approaches for Alzheimer's disease (AD) diagnosis face a fundamental challenges. Clinical assessments are expensive and invasive, leaving ground truth labels available for only a fraction of neuroimaging datasets. We…

Machine Learning · Computer Science 2026-03-23 Alireza Moayedikia , Sara Fin

We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-ICU patients using ~200 variables (vitals, lab results, assessments, ...). There are several missing predictor values for…

Large-scale multimodal models have shown excellent performance over a series of tasks powered by the large corpus of paired multimodal training data. Generally, they are always assumed to receive modality-complete inputs. However, this…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Lianyu Hu , Tongkai Shi , Wei Feng , Fanhua Shang , Liang Wan

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

Machine Learning · Computer Science 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Missing modality issues are common in real-world applications, arising from factors such as equipment failures and privacy concerns. When fine-tuning pre-trained models on downstream datasets with missing modalities, performance can degrade…

Machine Learning · Computer Science 2025-03-04 Zirun Guo , Shulei Wang , Wang Lin , Weicai Yan , Yangyang Wu , Tao Jin

Electroencephalography (EEG)-based emotion recognition suffers from severe performance degradation when models are transferred across heterogeneous datasets due to physiological variability, experimental paradigm differences, and device…

Machine Learning · Computer Science 2026-03-31 Guangli Li , Canbiao Wu , Na Tian , Li Zhang , Zhen Liang

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

The Internet of Things (IoT) ecosystem generates vast amounts of multimodal data from heterogeneous sources such as sensors, cameras, and microphones. As edge intelligence continues to evolve, IoT devices have progressed from simple data…

Machine Learning · Computer Science 2025-05-23 Heqiang Wang , Xiang Liu , Xiaoxiong Zhong , Lixing Chen , Fangming Liu , Weizhe Zhang

Early and accurate diagnosis of Alzheimer Disease is critical for effective clinical intervention, particularly in distinguishing it from Mild Cognitive Impairment, a prodromal stage marked by subtle structural changes. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Fahad Mostafa , Kannon Hossain , Hafiz Khan

In this paper, we propose SimMLM, a simple yet powerful framework for multimodal learning with missing modalities. Unlike existing approaches that rely on sophisticated network architectures or complex data imputation techniques, SimMLM…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Sijie Li , Chen Chen , Jungong Han

Healthcare relies on multiple types of data, such as medical images, genetic information, and clinical records, to improve diagnosis and treatment. However, missing data is a common challenge due to privacy restrictions, cost, and technical…

Machine Learning · Computer Science 2025-03-13 Nazanin Moradinasab , Saurav Sengupta , Jiebei Liu , Sana Syed , Donald E. Brown

Multi-modal class-incremental learning (MMCIL) seeks to leverage multi-modal data, such as audio-visual and image-text pairs, thereby enabling models to learn continuously across a sequence of tasks while mitigating forgetting. While…

Machine Learning · Computer Science 2025-01-17 Xianghu Yue , Yiming Chen , Xueyi Zhang , Xiaoxue Gao , Mengling Feng , Mingrui Lao , Huiping Zhuang , Haizhou Li

We propose a novel framework for Alzheimer's disease (AD) detection using brain MRIs. The framework starts with a data augmentation method called Brain-Aware Replacements (BAR), which leverages a standard brain parcellation to replace…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Mehmet Saygın Seyfioğlu , Zixuan Liu , Pranav Kamath , Sadjyot Gangolli , Sheng Wang , Thomas Grabowski , Linda Shapiro

Disease modifying therapies for Alzheimer's disease demand precise timing decisions, yet current predictive models require longitudinal observations and provide no uncertainty quantification, rendering them impractical at the critical first…

Machine Learning · Computer Science 2026-04-13 Alireza Moayedikia , Sara Fin , Uffe Kock Wiil

This paper introduces MMMU-Pro, a robust version of the Massive Multi-discipline Multimodal Understanding and Reasoning (MMMU) benchmark. MMMU-Pro rigorously assesses multimodal models' true understanding and reasoning capabilities through…

Computation and Language · Computer Science 2025-05-23 Xiang Yue , Tianyu Zheng , Yuansheng Ni , Yubo Wang , Kai Zhang , Shengbang Tong , Yuxuan Sun , Botao Yu , Ge Zhang , Huan Sun , Yu Su , Wenhu Chen , Graham Neubig

Patient representation learning based on electronic health records (EHR) is a critical task for disease prediction. This task aims to effectively extract useful information on dynamic features. Although various existing works have achieved…

Machine Learning · Computer Science 2024-01-02 Ziyue Yu , Jiayi Wang , Wuman Luo , Rita Tse , Giovanni Pau

Large-scale, cross-species plant distribution prediction plays a crucial role in biodiversity conservation, yet modeling efforts in this area still face significant challenges due to the sparsity and bias of observational data.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Haixu Liu , Yufei Wang , Tianxiang Xu , Chuancheng Shi , Hongsheng Xing

The automatic early diagnosis of prodromal stages of Alzheimer's disease is of great relevance for patient treatment to improve quality of life. We address this problem as a multi-modal classification task. Multi-modal data provides richer…

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